High-grade Squamous Intraepithelial Lesion
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Evaluation of NWRD08 for HPV-16 and/or HPV-18 Related Cervical HSIL [Phase 2]
A Phase 2 clinical trial evaluating NWRD08 for HPV-16/18-related cervical HSIL is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Does Hr-HPV Status Influence the 2011 IFCPC Nomenclature and Swede Score's Capacity to Diagnose Precancerous Lesions?
A completed clinical trial evaluated whether hr-HPV status influences the 2011 IFCPC nomenclature and Swede Score in diagnosing precancerous…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions [Phase 3]
Phase 3 randomized trial comparing imiquimod, fluorouracil, or observation in HIV-positive individuals with high-grade anal intraepithelial …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China
This clinical trial in China is investigating how HPV integration affects prognosis in young women with cervical intraepithelial neoplasia g…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: A Multicenter Randomized Controlled Study of Photoelectric Detection in Cervical Cancer Screening [NA]
Multicenter randomized controlled study evaluating photoelectric detection in cervical cancer screening; the trial status is not yet recruit…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: A Multicenter Real-world Study of Screening of Cervical Cancer Based on Photoelectric Detection
A multicenter real-world study is planned to screen cervical cancer using photoelectric detection; the trial is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2 [Phase 2]
Phase 2 trial of VGX-3100 delivered intramuscularly with electroporation for HPV-16/18 associated HSIL in HIV-seronegative individuals; stud…
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CLINICAL_TRIALS trial_result · 2022-07-13Clinical Trial Update: An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) [Phase 1, Phase 2]
Phase 1/2 exploratory study evaluating safety and immunogenicity of HPV16+ immunotherapy VB10.16 in women with high-grade cervical intraepit…
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Study of Pomalidomide in Anal Cancer Precursors [Phase 2]
Phase 2 study investigating pomalidomide in high-grade squamous intraepithelial lesion (HSIL) precursors; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection [Phase 1]
A Phase 1 study evaluating topical ABI-1968 in subjects with precancerous anal lesions caused by HPV has completed.
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CLINICAL_TRIALS trial_result · 2017-10-05Clinical Trial Update: A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand [Phase 2]
Phase 2 trial evaluating circumferential anal canal radiofrequency ablation for high-grade anal intraepithelial neoplasia using the BARRX an…
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CLINICAL_TRIALS trial_result · 2013-06-03Clinical Trial Update: SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells [Phase 2]
Phase 2 clinical trial of the SGN-00101 vaccine for HPV-related cervical cell abnormalities has completed.