Clinical Trial Update: Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG) [Phase 1, Phase 2]

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Summary

A Phase 1/2 clinical trial is evaluating a combination of ADI-PEG 20, temozolomide, and radiotherapy for newly diagnosed high-grade glioma, including glioblasto…

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Diseases / indications

• Diffuse Hemispheric Glioma H3 G34-mutant
• Diffuse Midline Glioma H3 K27-altered
• Glioblastoma
• High-grade Glioma

Drugs mentioned

• ADI-PEG 20 (pegylated arginine deiminase)
• Temodar (Temozolomide)

Snippet

Sponsor: Sabine Mueller, MD, PhD | Conditions: Glioblastoma, High-Grade Glioma (WHO III-IV) | Phase 1, Phase 2 | Status: NOT_YET_RECRUITING