Hepatosplenic T-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas [Phase 1, Phase 2]
A study of DR-01 by Dren Bio is ongoing in Phase 1/Phase 2 to treat several T-cell and NK-cell lymphomas, with recruitment currently underwa…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) [Phase 1]
A Phase 1 clinical trial is evaluating CCR4-directed CAR T cells in CCR4-expressing mature T-cell malignancies, including peripheral T-cell …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency [NA]
A Mayo Clinic-sponsored clinical trial evaluates cholecalciferol (vitamin D3) for improving survival in patients with newly diagnosed cancer…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL) [Phase 2]
This Phase II study evaluates single-agent Brentuximab Vedotin in relapsed/refractory CD30-low mature T-cell lymphomas; the trial has comple…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study of pembrolizumab plus pralatrexate in relapsed or refractory peripheral T-cell lymphomas…
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CLINICAL_TRIALS trial_result · 2023-04-19Clinical Trial Update: Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma [Phase 2]
Phase 2 trial evaluating brentuximab vedotin in combination chemotherapy for CD30-positive peripheral T-cell lymphomas reports results poste…
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CLINICAL_TRIALS withdrawal · 2023-02-21Clinical Trial Update: CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) [Phase 2, Phase 3]
Clinical trial CELTIC-1 evaluating cerdulatinib in relapsed/refractory peripheral T-cell lymphoma has been withdrawn from the study.
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CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating combination chemotherapy with lenalidomide in newly diagnosed peripheral T-cell lymphoma (multiple subtypes) ha…
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CLINICAL_TRIALS trial_result · 2021-03-04Clinical Trial Update: A Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL) [Phase 4]
A Phase 4 study sponsored by Janssen banked samples from Crohn's disease and ulcerative colitis patients to identify biomarkers that may pre…
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating everolimus and lenalidomide in relapsed or refractory non-Hodgkin or Hodgkin lymphoma; results posted.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: CEOP/IVE/GDP Compared With CEOP as the First-line Therapy for Newly Diagnosed Adult Patients With PTCL [Phase 2]
Phase 2 trial comparing CEOP/IVE/GDP to CEOP as first-line therapy for adults with peripheral T-cell lymphoma subtypes; status currently unk…
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial evaluating combination chemotherapy with pralatrexate as first-line therapy for non-Hodgkin lymphomas, including various T-cel…
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: CTOP/ITE/MTX Compared With CHOP as the First-line Therapy for Newly Diagnosed Young Patients With T Cell Lymphoma [Phase 4]
A Phase 4 clinical trial compares the CTOP/ITE/MTX regimen against CHOP as first-line therapy for newly diagnosed young patients with variou…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Gemcitabine Hydrochloride, Carboplatin, Dexamethasone, and Rituximab in Treating Patients With Previously Treated Lymphoid Malignancies [Phase 2]
A Phase 2 trial evaluating a combination of gemcitabine, carboplatin, dexamethasone, and rituximab in patients with previously treated lymph…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy in CD7 Positive Leukemia and Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating CAR-pNK cell immunotherapy for CD7-positive leukemias and lymphomas. The available snippet does n…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Alisertib in Treating Patients With Relapsed or Refractory Peripheral T-Cell Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial sponsored by the National Cancer Institute evaluated alisertib for relapsed or refractory peripheral T-cell non-Hodgkin lymp…
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial evaluating sorafenib tosylate in patients with recurrent aggressive non-Hodgkin lymphomas has completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Study of Bortezomib and Panobinostat in Treating Patients With Relapsed/Refractory Peripheral T-cell Lymphoma or NK/T-cell Lymphoma [Phase 2]
A completed Phase 2 study evaluating the combination of bortezomib and panobinostat in relapsed or refractory peripheral T-cell lymphomas an…
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CLINICAL_TRIALS trial_result · 2013-12-03Clinical Trial Update: Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma [Phase 1]
Phase 1 study evaluating the combination of bortezomib and azacitidine in adults with relapsed or refractory T-cell lymphomas; the trial is …
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Observational Study on the Occurrence of Hepatosplenic T-cell Lymphoma in Patients of Netherlands
Completed observational study in the Netherlands evaluating the occurrence of Hepatosplenic T-cell Lymphoma among patients.