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A Phase I/II Study of the Histone Deacetylase (HDAC) Inhibitor LBH589 (Panobinostat) in Combination With mTOR Inhibitor RAD001 (Everolimus) in Patients With Relapsed Multiple Myeloma or Lymphoma

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Record identity and dates

Source
ClinicalTrials.gov
Source record ID
NCT00918333
Title field or adapter rule
protocolSection.identificationModule.officialTitle
Ingested At
2026-04-28T10:37:47.537714+00:00
Published At
2018-05-18T00:00:00+00:00
Record Updated At
2020-03-10
Results Posted At
2018-05-18
Timestamp Basis
source retrieval time was not retained by the feed adapter
Date limitation
source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions
["Adult Nasal Type Extranodal NK/T-cell Lymphoma", "Anaplastic Large Cell Lymphoma", "Angioimmunoblastic T-cell Lymphoma", "B-cell Adult Acute Lymphoblastic Leukemia", "Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue", "Hepatosplenic T-cell Lymphoma", "Nodal Marginal Zone B-cell Lymphoma", "Post-transplant Lymphoproliferative Disorder", "Primary Central Nervous System Non-Hodgkin Lymphoma", "Recurrent Adult Acute Lymphoblastic Leukemia", "Recurrent Adult Burkitt Lymphoma", "Recurrent Adult Diffuse Large Cell Lymphoma", "Recurrent Adult Hodgkin Lymphoma", "Recurrent Adult Lymphoblastic Lymphoma", "Recurrent Adult T-cell Leukemia/Lymphoma", "Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma", "Recurrent Grade 1 Follicular Lymphoma", "Recurrent Grade 2 Follicular Lymphoma", "Recurrent Grade 3 Follicular Lymphoma", "Recurrent Mantle Cell Lymphoma", "Recurrent Marginal Zone Lymphoma", "Recurrent Mycosis Fungoides/Sezary Syndrome", "Recurrent Small Lymphocytic Lymphoma", "Refractory Chronic Lymphocytic Leukemia", "Refractory Multiple Myeloma", "Splenic Marginal Zone Lymphoma", "T-cell Adult Acute Lymphoblastic Leukemia", "Waldenstr\u00f6m Macroglobulinemia"]
protocolSection.statusModule.lastUpdatePostDateStruct.date
"2020-03-10"
protocolSection.identificationModule.nctId
"NCT00918333"
protocolSection.identificationModule.officialTitle
"A Phase I/II Study of the Histone Deacetylase (HDAC) Inhibitor LBH589 (Panobinostat) in Combination With mTOR Inhibitor RAD001 (Everolimus) in Patients With Relapsed Multiple Myeloma or Lymphoma"
protocolSection.statusModule.overallStatus
"COMPLETED"
protocolSection.designModule.phases
["PHASE1", "PHASE2"]
protocolSection.statusModule.resultsFirstPostDateStruct.date
"2018-05-18"

Study condition terms

  • Adult Nasal Type Extranodal NK/T-cell Lymphoma (protocolSection.conditionsModule.conditions)
  • Anaplastic Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
  • Angioimmunoblastic T-cell Lymphoma (protocolSection.conditionsModule.conditions)
  • B-cell Adult Acute Lymphoblastic Leukemia (protocolSection.conditionsModule.conditions)
  • Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue (protocolSection.conditionsModule.conditions)
  • Hepatosplenic T-cell Lymphoma (protocolSection.conditionsModule.conditions)
  • Nodal Marginal Zone B-cell Lymphoma (protocolSection.conditionsModule.conditions)
  • Post-transplant Lymphoproliferative Disorder (protocolSection.conditionsModule.conditions)
  • Primary Central Nervous System Non-Hodgkin Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Adult Acute Lymphoblastic Leukemia (protocolSection.conditionsModule.conditions)
  • Recurrent Adult Burkitt Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Adult Diffuse Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Adult Hodgkin Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Adult Lymphoblastic Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Adult T-cell Leukemia/Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Grade 1 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Grade 2 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Grade 3 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Mantle Cell Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Marginal Zone Lymphoma (protocolSection.conditionsModule.conditions)
  • Recurrent Mycosis Fungoides/Sezary Syndrome (protocolSection.conditionsModule.conditions)
  • Recurrent Small Lymphocytic Lymphoma (protocolSection.conditionsModule.conditions)
  • Refractory Chronic Lymphocytic Leukemia (protocolSection.conditionsModule.conditions)
  • Refractory Multiple Myeloma (protocolSection.conditionsModule.conditions)
  • Splenic Marginal Zone Lymphoma (protocolSection.conditionsModule.conditions)
  • T-cell Adult Acute Lymphoblastic Leukemia (protocolSection.conditionsModule.conditions)
  • Waldenström Macroglobulinemia (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.