Hepatorenal Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome [Phase 2]
Phase 2 trial evaluating ambrisentan, an endothelin receptor antagonist, for hepatorenal syndrome; the study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Comparison of Terlipressin Versus Octreotide in Patients With Hepatorenal Syndrome [NA]
A completed clinical trial comparing terlipressin versus octreotide in patients with hepatorenal syndrome.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury [NA]
The trial evaluated the role of echocardiography in the management of cirrhotic patients with hepatorenal syndrome and acute kidney injury. …
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease
Terlipressin was studied in a completed trial for combined hepatorenal syndrome in patients with signs of chronic kidney disease.
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I [NA]
The clinical trial evaluating the Selective Cytopheretic Device (SCD) for acute kidney injury and hepatorenal syndrome Type I has been suspe…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients [Phase 2, Phase 3]
NEPH-ROSIS, a Phase 2/3 pilot trial for treating acute kidney injury in hospitalized cirrhosis patients, has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) [Phase 3]
Phase 3 INFUSE trial evaluating terlipressin for hepatorenal syndrome with acute kidney injury in liver transplant candidates has completed …
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury [Phase 2]
Phase 2 trial assessing OCE-205 in participants with cirrhosis and ascites who developed hepatorenal syndrome-acute kidney injury has comple…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome [Phase 2]
Phase 2 clinical trial comparing R2R01 plus terlipressin versus terlipressin alone in patients with hepatorenal syndrome and acute kidney in…
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CLINICAL_TRIALS trial_result · 2023-05-09Clinical Trial Update: Terlipressin Infusion Alone Vs Terlipressin With Noradrenaline Infusion In The Treatment of Hepatorenal Syndrome Type 1 [Phase 3]
Phase 3 trial comparing terlipressin infusion alone versus terlipressin with noradrenaline infusion for Type 1 hepatorenal syndrome; the stu…
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin [Phase 3]
Phase 3 trial assessing reversal of Hepatorenal Syndrome Type 1 with terlipressin; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-11-21Clinical Trial Update: Rifaximin Prophylaxis for Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome in Cirrhotic Patients [Phase 2]
Phase 2 trial update on rifaximin prophylaxis for spontaneous bacterial peritonitis and hepatorenal syndrome in cirrhotic patients with asci…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1 [Phase 3]
Phase 3 trial evaluating terlipressin for hepatorenal syndrome type 1 has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline [NA]
Clinical trial update on treating Hepatorenal Syndrome with pentoxifylline; study is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure [NA]
Completed clinical trial comparing noradrenaline (norepinephrine) versus terlipressin for the response rate in hepatorenal syndrome among pa…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Study of Terlipressin Versus Placebo to Treat Hepatorenal Syndrome Type 1 [Phase 3]
A Phase 3 study comparing terlipressin to placebo for hepatorenal syndrome Type 1 has completed.
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients [Phase 2]
Phase 2 safety and pharmacokinetics update for Ifetroban in patients with Hepatorenal Syndrome, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: A Phase 1 Study of LJPC-501 in Patients With Hepatorenal Syndrome [Phase 1]
La Jolla Pharmaceutical's Phase 1 study of LJPC-501 in patients with Hepatorenal Syndrome was terminated.
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CLINICAL_TRIALS trial_result · 2015-07-03Clinical Trial Update: The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial Pressure [Phase 4]
Phase 4 clinical trial assessing whether terlipressin can prevent Type 2 hepatorenal syndrome by improving mean arterial pressure.
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Single Pass Albumin Dialysis in Patients With Cirrhosis [Phase 1, Phase 2]
Clinical trial update indicating completion of Phase 1 and Phase 2 studies of Single Pass Albumin Dialysis in patients with cirrhosis and re…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome [Phase 2, Phase 3]
The document reports a Phase 2/3 clinical trial comparing intravenous bolus administration of terlipressin to continuous intravenous infusio…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome [Phase 2, Phase 3]
A Phase 2/Phase 3 randomized trial comparing terlipressin plus albumin to midodrine plus octreotide for hepatorenal syndrome in cirrhosis ha…
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CLINICAL_TRIALS trial_result · 2013-09-05Clinical Trial Update: Treatment of Type-1 Hepatorenal Syndrome Associated With Sepsis [NA]
A clinical trial evaluating treatment for Type-1 Hepatorenal Syndrome associated with sepsis has completed.
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: TYPE 2 HEPATORENAL SYNDROME [Phase 3]
Phase 3 trial assessing the safety and efficacy of terlipressin plus norepinephrine for Type 2 hepatorenal syndrome has completed.
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CLINICAL_TRIALS trial_result · 2009-02-18Clinical Trial Update: Role Of Angiogenic Factors In The Development Of Hepatorenal Syndrome [NA]
A clinical trial examining angiogenic factors in the development of hepatorenal syndrome (NCT00734136) was terminated by the sponsor (Lahey …