Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion [Phase 2]
Phase 2 trial evaluating hepatic arterial idarubicin with lipiodol emulsion for hepatocellular carcinoma in cirrhosis; the study (NCT0372763…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma [Phase 1]
A Phase 1 clinical trial evaluating ALN-BCAT in patients with hepatocellular carcinoma (advanced or metastatic) is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Efficacy and Safety Comparison Between Intensified Therapy and Conversion Therapy For Advanced HCC After Failure of First-line [Phase 2]
This document provides a status update on a Phase 2 clinical trial comparing intensified therapy versus conversion therapy for advanced hepa…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Stereotactic Body Radiation Therapy (SBRT) Efficiency and Toxicity in Liver Cancer [NA]
This clinical trial update reports on the use of stereotactic body radiation therapy (SBRT) for liver cancer and liver metastases, focusing …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: HAI or IV of Adebrelimab, Combined With Bevacizumab and HAI of FOLFOX for Advanced Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating Adebrelimab in combination with Bevacizumab and hepatic artery infusion of FOLFOX for advanced unresectable hepatoc…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Volatile Organic Compounds for the Assessment of Liver Disease
A completed clinical trial evaluating volatile organic compounds for the assessment of liver disease.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating dual-target GPC3/B7-H3 CAR-NK cells for advanced hepatocellular carc…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: TACE or Ablation Combined With Sintilimab and Ipilimumab N01 as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With Intermediate-High Recurrence Risk [Phase 2]
A Phase 2 trial evaluating neoadjuvant therapy consisting of TACE or ablation plus Sintilimab and Ipilimumab for resectable hepatocellular c…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Dose-escalation of Regorafenib in Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 dose-escalation trial of regorafenib in advanced hepatocellular carcinoma is ongoing but not currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors [Phase 1]
A Phase 1 study is evaluating tolerability, safety, and pharmacokinetics of AST-201 in patients with GPC3-positive advanced solid tumors; th…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Intelligence System for Predicting Atezolizumab-Bevacizumab Response and Clinical Outcomes in Unresectable Hepatocellular Carcinoma
A clinical trial update describes an intelligence system intended to predict response and outcomes to atezolizumab-bevacizumab in unresectab…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Sintilimab Combined With Bevacizumab Biosimilar as Adjuvant Treatment After Resection of Ruptured Hepatocellular Carcinoma (CLEAR-2) [Phase 2]
Phase 2 trial investigating sintilimab plus a bevacizumab biosimilar as adjuvant therapy after resection of ruptured hepatocellular carcinom…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection [Phase 2]
Phase 2 trial assessing the imaging tracer 18F-FAPI-74 for cancer detection across multiple indications; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: TheraSphere With Durvalumab and Tremelimumab for HCC [Phase 2]
A Phase 2 trial evaluating TheraSphere in combination with durvalumab and tremelimumab for hepatocellular carcinoma is active but not recrui…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Optimizing Y90 Therapy for Radiation Lobectomy
Northwestern University sponsors a trial to optimize Y-90 radioembolization for radiation lobectomy in hepatocellular carcinoma to improve s…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Clinical Study on the Safety, Tolerability and Efficacy of Neoantigen-based Personalized mRNA Therapy iNeo-Vac-R01 Plus PD-1 Inhibitor in Adjuvant Treatment of Liver Cancer Post Radical Resection [Phase 1, Phase 2]
This document updates a Phase 1/2 clinical study evaluating iNeo-Vac-R01, a neoantigen-based personalized mRNA therapy, in combination with …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Development of a Neuronal Microscope [NA]
Clinical trial NCT06311396, sponsored by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, titled 'Development of a Neuronal Micro…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: IIT2025-03-YANG-LIFT-HCC [Phase 2]
Phase 2 IIT2025-03-YANG-LIFT-HCC trial for hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma [Phase 2]
This is a Phase 2 clinical trial evaluating regorafenib in combination with Yttrium-90 radioembolization for unresectable hepatocellular car…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Phase 2 Study of WGI-0301 Plus Nivolumab in Patients With HCC and RCC [Phase 2]
This Phase 2 trial evaluates WGI-0301 in combination with nivolumab in patients with hepatocellular carcinoma and renal cell carcinoma. The …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Lenvatinib or Regorafenib for Advanced Hepatocellular Carcinoma After Immunotherapy (REVIVE) [Phase 2]
This is a Phase 2 clinical trial (REVIVE) evaluating lenvatinib or regorafenib for advanced hepatocellular carcinoma after immunotherapy; th…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC) [Phase 1]
This clinical trial update describes a Phase 1 study evaluating adverse events and changes in disease activity for intravenous ABBV-324 in a…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ultra-stable Iodized Oil-Chemo Embolization Seq Thermal Ablation in Early Liver Ca [NA]
Clinical trial update for NCT07493070 evaluating ultra-stable iodized oil chemoembolization followed by sequential thermal ablation in early…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Cemiplimab +/- Fianlimab Post Y90 Radioembolization in Patients With Hepatocellular Carcinoma [Phase 1]
A Phase 1 trial evaluating cemiplimab with or without fianlimab following Y-90 radioembolization in patients with hepatocellular carcinoma.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Fostrox Plus Lenvatinib vs Lenvatinib in Advanced Hepatocellular Carcinoma After First-line Immunotherapy [Phase 2]
This is a Phase 2 trial comparing Fostrox plus lenvatinib versus lenvatinib alone in advanced hepatocellular carcinoma after failure of firs…