Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial [Phase 3]
A Phase 3 trial is evaluating immunotherapy with or without stereotactic body radiation therapy in adults with advanced hepatocellular carci…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC [Phase 3]
This Phase 3 trial investigates durvalumab and tremelimumab with or without lenvatinib in combination with transarterial chemoembolization f…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Regorafenib After Treatment Failure of First Line Immune Checkpoint Inhibitor Treatment in Advanced Hepatocellular Carcinoma Patients [Phase 2]
Phase 2 clinical trial evaluating regorafenib after failure of first-line immune checkpoint inhibitors in advanced hepatocellular carcinoma.…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies [Phase 1]
Phase 1 clinical trial evaluating GPC3-targeted CAR-T cell therapy in advanced GPC3-expressing solid tumors, including hepatocellular carcin…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor [Phase 1]
A Phase 1 trial to evaluate the safety, tolerability, and pharmacokinetics of ABSK-011 in patients with advanced liver cancer.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Prospective, Single-Arm, Exploratory Study of the Safety and Efficacy of Neoadjuvant Treatment With QL1706, an Anti-PD-1/Anti-CTLA-4 Bispecific Antibody, in Resectable Stage IB and IIA Hepatocellular Carcinoma With High Recurrence Risk [Phase 2]
A Phase 2, single-arm exploratory study evaluating the safety and efficacy of QL1706, a PD-1/CTLA-4 bispecific antibody, as neoadjuvant ther…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Regorafenib After Failure of Lenvatinib in Patients With Unresectable HCC: The RELEVANT-HCC Trial [Phase 2]
Phase 2 clinical trial evaluating regorafenib for unresectable hepatocellular carcinoma after lenvatinib failure (RELEVANT-HCC); the study i…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours [Phase 1, Phase 2]
A first-in-human study of AZD9793 in patients with advanced or metastatic solid tumours is currently recruiting. The trial includes hepatoce…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TTI-101 as monotherapy and in combination for locally advanced or metastatic, unresectable hepatocellu…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma [Phase 3]
Phase 3 clinical trial update evaluating nivolumab in combination with ipilimumab for advanced hepatocellular carcinoma is ongoing (active, …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors [Phase 1]
Phase 1 trial evaluating an IL-15/IL-21 armored GPC3-targeted CAR-T cell therapy for pediatric solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients [Phase 2]
Ongoing Phase 2 neoadjuvant trial evaluating cemiplimab for resectable non-small cell lung cancer, hepatocellular carcinoma, and head and ne…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating Y-90 radioembolization in combination with durvalumab, tremelimumab, and zanzalintinib for unresectable and locally…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Trial for Hepatocellular Carcinoma Adjuvant Treatment by Lipiocis [Phase 3]
A Phase 3 trial evaluating Lipiocis as adjuvant treatment for hepatocellular carcinoma has completed; sponsor information includes ANRS and …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer [Phase 3]
A Phase 3 trial sponsored by NRG Oncology is evaluating proton versus photon radiation therapy for hepatocellular carcinoma, including recur…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer
ClinicalTrials.gov entry for an exosome-based liquid biopsy to differentiate hepatocellular carcinoma from intrahepatic cholangiocarcinoma, …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis [Phase 2]
Phase 2 study evaluating atezolizumab with or without bevacizumab in patients with unresectable hepatocellular carcinoma and Child-Pugh B7/B…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: TSR-022 (Anti-TIM-3 Antibody) and TSR-042 (Anti-PD-1 Antibody) in Patients With Liver Cancer [Phase 2]
Phase 2 trial update for TSR-022 (anti-TIM-3) and TSR-042 (anti-PD-1) in adults with primary liver cancer; the study status is Active Not Re…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC [Phase 2]
Phase 2 study of RP2 in combination with second-line therapy for locally advanced or metastatic hepatocellular carcinoma and biliary tract c…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases [Phase 2]
Phase 2 clinical trial (BITS-TO-HCC) in recruiting evaluating hepatic arterial infusion chemotherapy plus iparomlimab and tuvonralimab with …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC [Phase 2]
Ongoing phase 2 trial evaluating enfortumab vedotin in advanced or metastatic colorectal cancer and hepatocellular carcinoma; study is curre…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Tislelizumab Monotherapy or Combined With Lenvatinib as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma. [Phase 2]
Phase 2 trial evaluating tislelizumab alone or with lenvatinib as neoadjuvant therapy for resectable hepatocellular carcinoma has completed.…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: TACE+RFA Versus TACE Alone for Intermediate-stage Hepatocellular Carcinoma [Phase 3]
Phase 3 trial comparing transarterial chemoembolization plus radiofrequency ablation versus TACE alone in intermediate-stage hepatocellular …
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Ipilimumab and Nivolumab With SBRT in Locally Advanced Hepatocellular Cancer [Phase 1]
Phase 1 trial updating the combo of ipilimumab and nivolumab with SBRT for locally advanced hepatocellular carcinoma; study status is not ye…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Large Language Models Assist in Tumor MDT [NA]
A clinical trial is recruiting to test the use of large language models to assist multidisciplinary tumor board discussions across multiple …