Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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EMA approval · 2025-03-28EMA Authorised: Nexavar (sorafenib) — Bayer AG
The EMA authorised Nexavar (sorafenib) for hepatocellular carcinoma and renal cell carcinoma. The decision date was 13 February 2025.
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Icariin Soft Capsules Combined With TACE as Adjuvant Therapy for HCC [Phase 2]
A Phase 2 clinical trial evaluating Icariin Soft Capsules in combination with Transarterial Chemoembolization as adjuvant therapy for hepato…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection [Phase 2]
Durvalumab is being studied in a Phase 2 trial for advanced hepatocellular carcinoma in patients with active chronic hepatitis B infection. …
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Atezolizumab and Bevacizumab Combination Recommended in a Multidisciplinary Consultation Meeting in Caen for Hepatocellular Carcinoma (ABCHCaen)
The clinical trial evaluating atezolizumab plus bevacizumab for hepatocellular carcinoma has completed, and the combination was recommended …
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy
A clinical study sponsored by Shanghai Zhongshan Hospital evaluating biomarkers and the molecular mechanisms of hepatocellular carcinoma aft…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: HAIC Compared With TACE in Huge Hepatocellular Carcinoma
Sun Yat-sen University is sponsoring a clinical trial comparing hepatic arterial infusion chemotherapy (HAIC) with transarterial chemoemboli…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Icaritin Soft Capsules+TACE+Immunotherapy+Targeted Therapy Versus TACE+Immunotherapy+Targeted Therapy for Unresectable Hepatocellular Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial protocol evaluating the addition of Icaritin soft capsules to TACE plus immunotherapy and targeted therapy for un…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Retrospective Clinical Validation of HepatoPredict
Retrospective clinical validation study of HepatoPredict by Ophiomics, with hepatocellular carcinoma as the primary condition; the trial is …
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Combined HAIC, TKI/Anti-VEGF and ICIs as Conversion Therapy for Unresectable Hepatocellular Carcinoma
This ClinicalTrials.gov entry outlines a study evaluating a combination approach using hepatic arterial infusion chemotherapy (HAIC), tyrosi…
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CLINICAL_TRIALS other · 2025-03-24Clinical Trial Update: Radioembolization of Primary and Secondary Liver Malignancies and The Effect On The Immune System [NA]
A terminated clinical trial evaluating radioembolization for hepatocellular carcinoma and secondary liver malignancies and its effects on th…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Phase I Study of OriC902 in Treatment of Advanced HCC [Phase 1]
Phase I trial of OriC902 for advanced hepatocellular carcinoma is currently recruiting, sponsored by Peking University.
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: 4D-MRI for Precision Medicine
A clinical trial update shows that a study using 4D-MRI for precision medicine is currently recruiting, focusing on liver cancer and lung ca…
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CLINICAL_TRIALS withdrawal · 2025-03-24Clinical Trial Update: Diagnostic Significance of Single Center, Open and Prospective Evaluation of <Sup>18<Sup>F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions of Primary Hepatocellular Carcinoma [NA]
Clinical trial NCT03636607 evaluating 18F-FDG PET/CT dynamic imaging and genomic sequencing for detecting metastatic lesions in hepatocellul…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCC [Phase 2]
A Phase 2 trial comparing immune checkpoint therapy with targeted therapy to reduce HBsAg levels in patients with HBsAg-positive advanced he…
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CLINICAL_TRIALS other · 2025-03-24Clinical Trial Update: The Overall Survival of Patients With Unresectable HCC in Real-life
A clinical trial (NCT03612726) is evaluating overall survival for patients with unresectable hepatocellular carcinoma in real-world settings…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers [Phase 1]
Phase 1 study of the oral STAT3 inhibitor TTI-101 in patients with advanced cancers has completed, with enrollment across multiple tumor typ…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: CXD101 in Immunotherapy-related Liver Cancer [Phase 2]
Phase 2 clinical trial of CXD101 for hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Study of Participants With Initially Unresectable Hepatocellular Carcinoma That is Treated With Atezolizumab and Bevacizumab Plus Transarterial Chemoembolization
This clinical trial update reports on a completed study evaluating the combination of atezolizumab and bevacizumab with transarterial chemoe…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) [NA]
PLATON, a platform for analyzing targetable tumor mutations, completed its pilot study evaluating its utility across hepatocellular carcinom…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: HCC Innervation Assessment
A status update for trial NCT06886763 on hepatocellular carcinoma indicates the study is active but not recruiting, focusing on innervation …
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: An Exploratory Clinical Study on Neoadjuvant Treatment of Hepatocellular Carcinoma with QL1706 Combined with Lenvatinib [Phase 2]
An exploratory Phase 2 clinical trial evaluating neoadjuvant treatment of hepatocellular carcinoma with QL1706 in combination with lenvatini…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: A Phase I Study of LXP1788 Injection with Advanced Solid Tumors. [Phase 1]
This Phase I trial is evaluating the safety and tolerability of LXP1788 Injection in adults with advanced solid tumors and is currently recr…
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CLINICAL_TRIALS withdrawal · 2025-03-18Clinical Trial Update: A Pilot Study For Patients Receiving Radiation Therapy for Liver Cancer [NA]
A pilot trial evaluating radiation therapy for hepatocellular carcinoma has been withdrawn.
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Immune Checkpoint Inhibitors and Anti-vascular Endothelial Growth Factor Antibody/tyrosine Kinase Inhibitors with or Without HAIC for Advanced HCC
A ClinicalTrials.gov entry describes a study evaluating immune checkpoint inhibitors with or without anti-VEGF antibody/tyrosine kinase inhi…
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CLINICAL_TRIALS withdrawal · 2025-03-18Clinical Trial Update: TT-4 As a Single Agent in Subjects with Advanced Selected Solid Tumors [Phase 1, Phase 2]
Tarus Therapeutics has withdrawn its TT-4 single-agent trial in advanced solid tumors across Phase 1 and Phase 2. The listed conditions incl…