Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Immune Checkpoint Inhibitors and Anti-vascular Endothelial Growth Factor Antibody/tyrosine Kinase Inhibitors with or Without TACE for Advanced HCC with Vascular Invasions
Clinical trial update on combining immune checkpoint inhibitors with anti-VEGF antibody/tyrosine kinase inhibitors, with or without TACE, fo…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Blood Salvage in Orthotopic Liver Transplantation With HCC [NA]
Clinical trial update on blood salvage during orthotopic liver transplantation for hepatocellular carcinoma; the study is currently active a…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCC
This document reports a clinical trial update on regional lymph node metastasis and survival outcomes in advanced hepatocellular carcinoma, …
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: BOLD MRI and FMISO PET for the Assessment of Hypoxic Tumor Microenvironment in Patients with Oligometastatic Liver Cancer Undergoing Yttirum-90 Selective Internal Radiation Therapy [EARLY_Phase 1]
This early-phase study evaluated imaging approaches (BOLD MRI and FMISO PET) to assess the hypoxic tumor microenvironment in patients with h…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Study of INCB086550 in Select Solid Tumors [Phase 2]
A Phase 2 trial evaluating INCB086550 across select solid tumors, including non-small cell lung cancer and urothelial carcinoma, was termina…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Case-Control Study of the Glycotest™ HCC Panel Vs AFP for the Detection of Early-stage Hepatocellular Carcinoma
ClinicalTrials.gov entry for a case-control study comparing the Glycotest HCC Panel to AFP for early detection of hepatocellular carcinoma; …
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma [Phase 3]
A Phase 3 study evaluating AK104 plus lenvatinib with transarterial chemoembolization versus TACE alone in incurable/non-metastatic hepatoce…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC [Phase 2]
A Phase II clinical trial evaluating AK104 in combination with Lenvatinib and transarterial chemoembolization (TACE) for unresectable, non-m…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Exploring the Knowledge, Attitudes, Behaviors and Perceived Barriers of Hepatologists Towards Non-invasive Hepatocellular Carcinoma Prediction Models in Hepatitis C Patients Who Achieved Sustained Virological Response Following Direct Acting Antivirals Therapy
A protocol-style clinical study assessing hepatologists' knowledge, attitudes, behaviors, and barriers toward non-invasive hepatocellular ca…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Anti-PD-1 Antibody AK105 in Patients With Selected Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial AK105 in selected advanced solid tumors has completed Phase 1/2; the summary does not provide efficacy or safety results.
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: A Phase III Study of AK104 as Adjuvant Therapy in HCC With High Risk of Recurrence After Curative Resection [Phase 3]
This is an update on a Phase 3 trial evaluating AK104 as adjuvant therapy for hepatocellular carcinoma patients at high risk of recurrence a…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Holmium-166 Transarterial Radioembolization for the Treatment of Hepatocellular Carcinoma
This clinical trial update indicates that Holmium-166 transarterial radioembolization for hepatocellular carcinoma is currently recruiting, …
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating PM8002 in combination with chemotherapy as first-line therapy for hepatocellular carcinoma; the study is c…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Characteristic and Survival Outcomes in Hepatocellular Carcinoma Patients: on Top of Viral Hepatitis Versus Combined Viral and Metabolic-Associated Steatotic Liver Disease
A registered clinical trial evaluating characteristics and survival outcomes in hepatocellular carcinoma comparing viral hepatitis–associate…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Plasma Sphingolipid Metabolites and Radiotherapy Efficacy in Hepatocellular Carcinoma
This is an ongoing clinical trial sponsored by Nanfang Hospital/Southern Medical University evaluating whether plasma sphingolipid metabolit…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy [Phase 2]
A Phase 2 neoadjuvant trial comparing atezolizumab/bevacizumab versus neoadjuvant radiation therapy in hepatocellular carcinoma with portal …
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer [NA]
This clinical trial compares standard SBRT dosing to radiobiologically-guided SBRT dosing for liver cancer and is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Efficacy and Safety of Radiotherapy in Oligoprogressive HCC Following First-line PD-1 Therapy [Phase 2]
Phase 2 trial evaluating the efficacy and safety of radiotherapy for oligoprogressive hepatocellular carcinoma after first-line PD-1 therapy…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Transarterial Chemoembolization (TACE) Versus TACE Plus Stereotactic Body Radiation Therapy (SBRT) in Liver Carcinoma [Phase 3]
A Phase 3 clinical trial comparing transarterial chemoembolization (TACE) alone versus TACE plus stereotactic body radiation therapy (SBRT) …
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CLINICAL_TRIALS withdrawal · 2025-03-11Clinical Trial Update: Chidamide + Regorafenib in Hepatocellular Carcinoma (HCC) [Phase 1, Phase 2]
A Phase 1/2 trial of chidamide plus regorafenib for hepatocellular carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Preliminary Antitumor Activity, Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma [Phase 2]
Phase 2 study evaluating the combination of tislelizumab and lenvatinib in hepatocellular carcinoma, reporting preliminary antitumor activit…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: First-in-Human Safety, Tolerability and Antitumour Activity Study of MTL-CEBPA in Patients With Advanced Liver Cancer [Phase 1]
This first-in-human Phase 1 trial reports safety, tolerability, and preliminary antitumor activity of MTL-CEBPA in patients with advanced he…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Patients With Locally Advanced or Metastatic HCC Failed or Intolerance to Standard Therapy [Phase 2]
This clinical trial update reports a Phase II study evaluating HLX43 in patients with locally advanced or metastatic hepatocellular carcinom…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Study of HBV-TCR T Cells (LioCyx-M) as Monotherapy or as Combination With Lenvatinib for HBV-related HCC [Phase 2]
Phase 2 study of HBV-TCR T Cells (LioCyx-M) as monotherapy or with Lenvatinib for HBV-related hepatocellular carcinoma; the trial is not yet…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Efficacy and Safety of Yttrium-90 Microspheres Selective Internal Radiotherapy Combined with Immune Checkpoint Inhibitors and Anti-angiogenesis Drugs Sequential HAIC for Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating Yttrium-90 microsphere radioembolization combined with immune checkpoint inhibitors, anti-angiogenesis dru…