Hepatocellular Carcinoma
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Efficacy and Safety of Liver Transplantation for Hepatocellular Carcinoma With Bile Duct Tumor Thrombus: a Single-arm, Multicenter, Prospective Study (HCC-BDTT in LT)
This clinical trial is a single-arm, multicenter, prospective study evaluating the efficacy and safety of liver transplantation for hepatoce…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC) [Phase 2]
Phase 2 study of YIV-906 in combination with Sorafenib for HBV-positive hepatocellular carcinoma has completed. It investigates the use of Y…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer or Other Select Solid Cancers [Phase 1]
A Phase 1 first-in-human study evaluated BAY3630942 after BAY3547922, focusing on distribution, pharmacokinetics, and safety. The trial in h…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: A Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma [Phase 2]
This update describes a Phase 2 study of the combination of atezolizumab and bevacizumab for unresectable hepatocellular carcinoma. The tria…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Pilot Study to Assess Lung Shunting of Yttrium-90 Microspheres Using PET/CT
Pilot study evaluating lung shunting of Yttrium-90 microspheres using PET/CT in patients with advanced liver cancer and liver metastases.
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Effect of Biejia-Ruangan Compound on Survival Rate and Recurrence Rate of Hepatocellular Carcinoma After Radical Treatment [Phase 4]
Phase 4 clinical trial evaluating the effect of Biejia-Ruangan Compound on survival and recurrence after radical treatment in hepatocellular…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma [Phase 1, Phase 2]
Eureka Therapeutics reports a Phase 1/2 trial recruiting pediatric patients with hepatoblastoma, hepatocellular carcinoma, and related liver…
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CLINICAL_TRIALS other · 2025-04-09Clinical Trial Update: SIRT Versus cTACE for Unresectable HCC (CHANCE2506) [NA]
Clinical trial comparing selective internal radiation therapy versus conventional transarterial chemoembolization for unresectable hepatocel…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: SIRT or TACE Plus Lenvatinib and PD-(L)1 Inhibitor in High Burden HCC
A study evaluating SIRT or TACE in combination with lenvatinib and a PD-1/PD-L1 inhibitor for unresectable hepatocellular carcinoma has comp…
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CLINICAL_TRIALS trial_result · 2025-04-07Clinical Trial Update: Lenvatinib Treatment in Waiting List of Liver Transplantation After TACE Failure in Patients With Hepatocellular Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating lenvatinib for patients with non-resectable hepatocellular carcinoma on the liver transplant waiting lis…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Extracellular RNA Markers of Liver Disease and Cancer
This ClinicalTrials.gov update reports on a Mayo Clinic-sponsored study investigating extracellular RNA markers in liver disease and cancer,…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer. [Phase 2, Phase 3]
A Phase II/III clinical trial is evaluating Transarterial Tirapazamine Embolization (TATE) versus conventional transarterial chemoembolizati…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: SH-LPS System in Preoperative Planning for Liver Resection [Phase 2, Phase 3]
The document reports an ongoing clinical trial evaluating the SH-LPS System for preoperative planning in liver resection, with Phase 2 and P…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Single Centre Prospective Evaluation of 68Gallium-FAPI PET/MRI in Hepatocellular Carcinoma [Phase 1]
Phase 1 prospective evaluation of Gallium-68 FAPI PET/MRI in hepatocellular carcinoma, currently recruiting at a single center.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Improving Hepatocellular Carcinoma Screening [NA]
A clinical trial is currently recruiting to improve hepatocellular carcinoma screening by evaluating MRI and contrast-enhanced ultrasound im…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Collection of Blood and Tissue Samples From Patients With Primary Liver Cancer.
This clinical trial update describes the collection of blood and tissue samples from patients with primary liver cancer to support research.…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: TACE Combined Surgery for the Resectable Huge HCC
Clinical trial update on transarterial chemoembolization (TACE) combined with surgery for resectable huge hepatocellular carcinoma. The stud…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies [Phase 1, Phase 2]
Phase 1/2 open-label study evaluating Alomfilimab (KY1044) alone and with atezolizumab in multiple advanced cancers. The trial was terminate…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation [NA]
The clinical trial update indicates completion of a study evaluating the combination of dexmedetomidine and esketamine for sedation during p…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Tumor Antigen Discovery for Innovative Cancer Immunotherapies in HCC: from Benchside to Bedside (HepAnt)
This update outlines an ongoing clinical trial initiative in hepatocellular carcinoma focused on identifying tumor antigens to support innov…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery [NA]
A three-arm clinical trial called TANGO-LIVER is evaluating nuclear growth observation in liver surgery and is currently recruiting particip…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Efficacy and Safety of Sintilimab Combined With Lenvatinib and HAIC for Neoadjuvant Therapy of Borderline Resectable HCC [Phase 2]
This clinical trial update describes a Phase 2 study of sintilimab in combination with lenvatinib and hepatic arterial infusion chemotherapy…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Cabozantinib in Patients With Hepatocellular Carcinoma (ACTION) [Phase 2]
The ACTION Phase 2 trial evaluating cabozantinib in hepatocellular carcinoma has completed, with results posted on 2025-03-30.
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: TARGETed Therapy Drug MONITOring in DIGestive Oncology [NA]
UNICANCER-sponsored clinical trial is recruiting a targeted therapy monitoring study in digestive oncology, including metastatic colorectal …
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Single-Cell Profiling of Liver-infiltrating Immune Cells of Patients with NASH- and Virus-related HCC: Implications for Immunotherapy
A completed single-cell profiling study of liver-infiltrating immune cells in hepatocellular carcinoma associated with MASLD or hepatitis C …