Hemophilia
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A [NA]
This clinical trial update notes a completed study comparing prophylaxis versus on-demand treatment in children with moderate to severe Hemo…
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CLINICAL_TRIALS trial_result · 2015-01-19Clinical Trial Update: Effekt-2 - Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Latin America
The document reports efficacy and safety data from long-term use of KOGENATE FS (recombinant factor VIII) for hemophilia A in Latin America.
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CLINICAL_TRIALS trial_result · 2015-01-05Clinical Trial Update: Prophylaxis Versus on Demand Treatment for Children With Hemophilia A [Phase 4]
Phase 4 trial comparing prophylaxis versus on-demand treatment in children with Hemophilia A has completed and posted results.
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CLINICAL_TRIALS trial_result · 2014-12-25Clinical Trial Update: Haemophilia Patients With Inhibitors Being Treated for Acute Joint Bleeds [Phase 2]
Phase 2 clinical trial update evaluating treatment of acute joint bleeds in patients with hemophilia A or B who have inhibitors; results hav…
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CLINICAL_TRIALS trial_result · 2014-12-18Clinical Trial Update: Assessment of the Risk of Inhibitor Formation in Previously Treated Patients With Severe Hemophilia A [Phase 4]
Phase 4 trial update from Bayer evaluating the risk of inhibitor formation in previously treated patients with severe Hemophilia A; the stud…
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CLINICAL_TRIALS trial_result · 2014-12-17Clinical Trial Update: Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A [Phase 3]
Phase 3 trial update for modified recombinant Factor VIII (OBI-1) in congenital Hemophilia A; study terminated with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-12-12Clinical Trial Update: Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A [Phase 3]
Phase 3 trial assessing safety, efficacy, and pharmacokinetics of recombinant FVIII Fc fusion protein in previously treated pediatric subjec…
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens [Phase 4]
Phase 4 clinical trial update investigating subclinical joint bleeding in Irish adults with severe Hemophilia A on personalized prophylaxis …
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Pharmacokinetics and Safety of a Single Intravenous Infusion of BAY 79-4980 [Phase 1]
This Phase 1 trial evaluated the pharmacokinetics and safety of a single intravenous infusion of BAY 79-4980 in Hemophilia A and has complet…
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CLINICAL_TRIALS trial_result · 2014-11-03Clinical Trial Update: Evaluation of the Reasons and Consequences of Bleeding in Late Teens and Early Adulthood Patients With Severe Hemophilia A
This completed Bayer-sponsored clinical trial evaluates the reasons for and consequences of bleeding in late teens and early adulthood patie…
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CLINICAL_TRIALS trial_result · 2014-10-31Clinical Trial Update: Efficacy and Safety of ADVATE Standard Prophylaxis to Hemophilia A [NA]
A clinical trial update evaluating the efficacy and safety of ADVATE Standard Prophylaxis in individuals with Hemophilia A, with status curr…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: A Study to Compare the Pharmacokinetics and Safety of Replenine®-VF, Replenine® or Other Factor IX in Haemophilia B [Phase 3]
A Phase 3 study comparing the pharmacokinetics and safety of Replenine®-VF, Replenine®, and other Factor IX products in Hemophilia B has com…
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: Early Prophylaxis Immunologic Challenge (EPIC) Study [Phase 3]
Phase 3 EPIC study in Hemophilia A was terminated; results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-09-17Clinical Trial Update: Post Marketing Observational Study of Reformulated BeneFIX
Post-marketing observational study of reformulated BeneFIX (recombinant coagulation factor IX) for Hemophilia B has completed and results we…
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CLINICAL_TRIALS trial_result · 2014-09-04Clinical Trial Update: Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B [Phase 3]
Phase 3 study of recombinant Factor IX Fc fusion protein (rFIXFc) in participants with severe Hemophilia B completed with results posted in …
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Study Evaluating Safety Of Patients Switching To ReFacto AF In Usual Care Settings [Phase 4]
Phase 4 study evaluating the safety of switching Hemophilia A patients to ReFacto AF in usual care; the trial was terminated with results po…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Subjects With Severe Hemophilia A [Phase 3]
Phase 3 trial evaluating recombinant Factor VIII Fc fusion protein (rFVIIIFc) in previously treated patients with severe Hemophilia A comple…
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Study of FVIIa Variant BAY86-6150 (B0189) in Subjects With Moderate or Severe Hemophilia Types A or B With or Without Inhibitors [Phase 1]
A Phase 1 study of the Factor VIIa variant BAY86-6150 (B0189) in adults with Hemophilia A or Hemophilia B (with or without inhibitors) has c…
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Kogenate FS Regulatory Post-Marketing Surveillance
A post-marketing surveillance trial for Bayer's Kogenate FS focusing on Hemophilia A has completed.
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Investigating Safety and Pharmacokinetics of NNC 0128-0000-2011 Compared to NNC 0128-0000-2021 in Healthy Male Subjects [Phase 1]
A Phase 1 study evaluating safety and pharmacokinetics of two investigational products, NNC 0128-0000-2011 and NNC 0128-0000-2021, in health…
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CLINICAL_TRIALS trial_result · 2014-07-11Clinical Trial Update: Impact of Conservative Treatment by Custom-made Orthoses in Patients With Haemophilic Ankle Arthropathy [Phase 4]
This Phase 4 clinical trial evaluated the impact of custom-made orthoses as conservative treatment for haemophilic ankle arthropathy, and th…
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Safety, Efficacy and Pharmacokinetics of GreenGene™ F to Previously Treated Patients With Severe Hemophilia A [Phase 3]
Phase 3 clinical trial update evaluating safety, efficacy, and pharmacokinetics of GreenGene F in previously treated patients with severe He…
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Individualized Prophylaxis for Severe Hemophilia A Children [NA]
This entry reports a clinical trial on individualized prophylaxis for children with severe Hemophilia A, sponsored by Beijing Children's Hos…
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Allogenic Bone Marrow Derived Mesenchymal Stem Cell Therapy in Cases of Hemophilia [Phase 1]
A Phase 1 clinical trial at Cairo University evaluating allogeneic bone marrow–derived mesenchymal stem cell therapy for hemophilia.
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Hemophilia Inhibitor Genetics Study (HIGS)
The Hemophilia Inhibitor Genetics Study (HIGS) clinical trial has completed, per sponsor Skane University Hospital.