Hemophilia with Inhibitors
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors [Phase 3]
A Phase 3 study evaluating Mim8 in adults and adolescents with Hemophilia A, with or without inhibitors, has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: rFVIIIFc (Elocta®) ITI Chart Review in Patients With Haemophilia A
This document reports a completed chart review study assessing immune tolerance induction using rFVIIIFc (Elocta) in patients with Hemophili…
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: An Exploration of the Impact of Emicizumab on the Lives of People With Haemophilia and Inhibitors and Their Families
A completed study examining how emicizumab affects daily life for people with Hemophilia A with inhibitors and their families, with results …
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: SS109 and NovoSeven ® PK / PD Profile, and Preliminary Efficacy and Safety of SS109 on Demand Treatment [Phase 1, Phase 2]
Phase 1/2 clinical trial update reporting PK/PD profiles for SS109 and NovoSeven on-demand use, with preliminary efficacy and safety data in…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: Pharmacokinetic-guided Dosing of Emicizumab [Phase 4]
Phase 4 clinical trial updating pharmacokinetic-guided dosing of emicizumab in people with Hemophilia A (with and without inhibitors) across…
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CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: A Pharmacokinetic and Clotting Activity Study of FVIII-PEGLip [Phase 2]
Phase 2 pharmacokinetic and clotting activity study of FVIII-PEGLip for Hemophilia A with inhibitors.
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CLINICAL_TRIALS trial_result · 2021-07-07Clinical Trial Update: A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study) [Phase 4]
Phase 4 study evaluating rFVIIIFc for immune tolerance induction in severe Hemophilia A patients with inhibitors; study completed with poste…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Clinical Trial Comparing a Biosimilar Eptacog Alfa With Novoseven, in Patients With Hemophilia With Inhibitors [Phase 3]
Phase 3 clinical trial comparing a biosimilar Eptacog alfa with NovoSeven in patients with hemophilia A or B with inhibitors has completed.
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CLINICAL_TRIALS trial_result · 2020-08-28Clinical Trial Update: A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa [Phase 3]
Phase III study assessing safety, pharmacokinetics, and efficacy of coagulation Factor VIIa in hemophilia A and B with inhibitors has comple…
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CLINICAL_TRIALS trial_result · 2020-05-29Clinical Trial Update: INdividualized ITI Based on Fviii(ATE) Protection by VWF [Phase 4]
Phase 4 trial update for individualized ITI based on FVIII protection by von Willebrand factor in Hemophilia A patients with inhibitors; tri…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Study of Recombinant Factor VIIa Fusion Protein (rVIIa-FP, CSL689) for On-demand Treatment of Bleeding Episodes in Patients With Hemophilia A or B With Inhibitors [Phase 2, Phase 3]
Phase 2/3 clinical trial update for recombinant factor VIIa fusion protein (rVIIa-FP, CSL689) evaluating on-demand treatment of bleeding in …
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Non-Interventional Study of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors
This non-interventional study evaluated on-demand NovoSeven for treating bleeds in patients with hemophilia A or B with inhibitors; the stud…
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Efficacy Study of Activated Prothrombin Complex for Prevention of Bleeds in Hemophilia A With Inhibitors [Phase 2, Phase 3]
A Phase 2/3 trial evaluating activated prothrombin complex concentrate for preventing bleeds in Hemophilia A patients with inhibitors has co…
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Impact of Pain on Functional Impairment and Quality of Life in Adults With Hemophilia
A completed clinical trial update examining how pain affects functional impairment and quality of life in adults with hemophilia.
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Safety and Tolerability of Intravenous Doses of Activated Recombinant Human Factor VII in Healthy Volunteers [Phase 1]
A Phase 1 trial evaluating the safety and tolerability of intravenous doses of activated recombinant human factor VII in healthy volunteers.…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia [Phase 2]
This Phase 2 clinical trial update evaluates the efficacy of NovoSeven for bleeding prophylaxis in people with hemophilia, including those w…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Prediction of the Efficacy of Activated Recombinant Human Factor VII in Adult Congenital Haemophilia A or B Patients With Inhibitors by Use of Thromboelastography [Phase 1]
Phase 1 trial evaluating whether thromboelastography can predict the efficacy of activated recombinant Factor VII (NovoSeven) in adults with…
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CLINICAL_TRIALS trial_result · 2011-12-19Clinical Trial Update: Observational Registry of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors
An observational registry evaluating NovoSeven as on-demand treatment for bleeds in patients with Hemophilia A or B with inhibitors; the stu…
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CLINICAL_TRIALS trial_result · 2011-07-25Clinical Trial Update: PROPACT: Retrospective Prophylaxis Patient Case Collection
PROPACT is a retrospective collection of prophylaxis cases; the study is completed and results have been posted by Novo Nordisk.
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CLINICAL_TRIALS trial_result · 2009-12-07Clinical Trial Update: International Immune Tolerance Study [NA]
The International Immune Tolerance Study for Hemophilia A with inhibitors has been terminated.