Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-12-14Clinical Trial Update: Clinical and Metabonomics Study on the Treatment of Heart Failure After Myocardial Infarction With Modified Wenxin Decoction [Phase 2]
Phase 2 clinical trial update evaluating the effects of Modified Wenxin Decoction on heart failure post-myocardial infarction.
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FDA approval · 2020-12-10FDA Approved: TRIAMTERENE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Zydus Pharmaceuticals (USA) Inc.)
The FDA approved a supplemental ANDA for Triamterene and Hydrochlorothiazide from Zydus Pharmaceuticals (USA) Inc., enabling the generic pro…
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Early Administration of Ivabradine in Children With Heart Failure [Phase 2]
Phase 2 trial update on early administration of ivabradine in children with acute heart failure and dilated cardiomyopathy.
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FDA approval · 2020-12-02FDA Approved: METOLAZONE — Original Application (Alembic Pharmaceuticals Limited)
Alembic Pharmaceuticals Limited's original application for metolazone received FDA approval, enabling the generic version to be marketed in …
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CLINICAL_TRIALS trial_result · 2020-12-02Clinical Trial Update: Heart Sounds Measurement Using the Wearable Cardioverter Defibrillator (HS-WCD) Study [NA]
A completed Clinical Trial study evaluating heart sounds measurement using the Wearable Cardioverter Defibrillator in patients with heart fa…
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CLINICAL_TRIALS trial_result · 2020-11-27Clinical Trial Update: Study of Reminding to Improve Medication Adherence in Heart Failure [NA]
Completed clinical trial studying reminders to improve medication adherence in patients with heart failure; results posted.
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CLINICAL_TRIALS trial_result · 2020-11-27Clinical Trial Update: Safety and Effectiveness of Drug up Titration by Nurses Specialized in Heart Failure (HF) Patients [NA]
Clinical trial update on the safety and effectiveness of drug titration by specialized heart failure nurses; completed with posted results.
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FDA approval · 2020-11-27FDA Approved: CHLORTHALIDONE — Original Application (Ajanta Pharma USA Inc.)
FDA approved Ajanta Pharma USA Inc.'s original application for a generic chlorthalidone product.
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FDA approval · 2020-11-25FDA Approved: METOPROLOL SUCCINATE — Original Application (Ascend Laboratories, LLC)
FDA approved Ascend Laboratories, LLC's metoprolol succinate extended-release tablets as an original application (generic).
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: Organized Program To Initiate Lifesaving Treatment In Hospitalized Patients With Heart Failure (OPTIMIZE-HF) [Phase 4]
A Phase 4 trial update for the OPTIMIZE-HF program investigating lifesaving treatment initiation in hospitalized heart failure patients.
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CLINICAL_TRIALS trial_result · 2020-11-18Clinical Trial Update: Post-market Study of Multi-Vector Left Ventricular Lead Performance in Chinese Patients With Chronic Heart Failure
A post-market study assessing the performance of a multi-vector left ventricular lead in Chinese patients with chronic heart failure has com…
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CLINICAL_TRIALS trial_result · 2020-11-17Clinical Trial Update: Monitoring Medication Adherence in Left Ventricular Assist Device Recipients [NA]
A completed clinical trial evaluating monitoring of medication adherence in recipients of left ventricular assist devices.
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CLINICAL_TRIALS trial_result · 2020-11-16Clinical Trial Update: Clinical Benefits in Optimized Remote HF Patient Management [NA]
Clinical trial update reporting benefits of optimized remote management for congestive heart failure patients.
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FDA approval · 2020-11-12FDA Approved: DIGOXIN — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
The FDA approved a supplemental application for Digoxin submitted by Amneal Pharmaceuticals of New York LLC.
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CLINICAL_TRIALS trial_result · 2020-11-10Clinical Trial Update: Diuretic and Natriuretic Effect of High-dose Spironolactone in Patients With Acute Heart Failure [Phase 4]
Phase 4 trial update investigating the diuretic and natriuretic effects of high-dose spironolactone in patients with acute heart failure and…
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FDA approval · 2020-11-06FDA Approved: METOPROLOL SUCCINATE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved a generic version of metoprolol succinate (Camber Pharmaceuticals) under an Original Application (ANDA 205541).
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CLINICAL_TRIALS trial_result · 2020-10-30Clinical Trial Update: Evaluation of ACUITY™ X4 Quadripolar Coronary Venous Leads and RELIANCE™ 4-FRONT Defibrillation Leads [NA]
Clinical trial update for ACUITY X4 quadripolar venous leads and RELIANCE 4-FRONT defibrillation leads in Cardiac Resynchronization Therapy …
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Prevention of Non-Surgical Bleeding by Management of HeartMate II Patients Without Antiplatelet Therapy [Phase 4]
Phase 4 trial updates prevention of non-surgical bleeding in HeartMate II patients without antiplatelet therapy, with results posted after c…
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects [Phase 2]
Phase 2 trial investigating nicotinamide riboside for skeletal muscle function in heart failure was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: IMMNC-HF: IntraMyocardial Injection of Bone Marrow MonoNuclear Cells in Heart Failure (HF) Patients [Phase 1, Phase 2]
Clinical trial update for IMMNC-HF investigating intraMYocardial injection of bone marrow mononuclear cells in heart failure patients across…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: The Effect of Neprilysin (LCZ696) on Exercise Tolerance in Patients With Heart Failure [Phase 4]
Phase 4 trial evaluating the effect of neprilysin inhibitor LCZ696 (sacubitril/valsartan) on exercise tolerance in patients with heart failu…
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CLINICAL_TRIALS withdrawal · 2020-10-22Clinical Trial Update: Spironolactone Safety in Dialysis Patients [Phase 4]
A Phase 4 trial evaluating spironolactone safety in dialysis patients has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-10-19Clinical Trial Update: Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF [Phase 3]
A Phase 3 trial evaluating clevidipine versus placebo or standard of care for dyspnea and blood pressure control in acute heart failure was …
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: The Effect of Sacubitril/Valsartan on Cardiovascular Events in Dialysis Patients and Efficacy Prediction of Baseline LVEF Value [Phase 4]
Phase 4 trial investigating the effect of sacubitril/valsartan on cardiovascular events in dialysis patients and predicting efficacy from ba…
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FDA approval · 2020-10-07FDA Approved: DIGOXIN — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved a supplemental application for digoxin filed by Sun Pharmaceutical Industries, Inc. to update the drug's labeling.