Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2021-02-12FDA Approved: METOPROLOL SUCCINATE — Original Application (Epic Pharma, LLC)
FDA approves the original application for metoprolol succinate as a generic extended-release beta-blocker indicated for hypertension and hea…
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: ENABLE CHF-PC (Comprehensive Heartcare For Patients and Caregivers) [NA]
Clinical trial update for ENABLE CHF-PC study focused on heart failure has completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-10Clinical Trial Update: Effect of W-3 Polyunsaturated Fatty Acids on Serum Albumin Concentration in Patients With Acute Heart Failure, Hypoalbuminemia, and High Inflammatory Activity [Phase 3]
Phase 3 trial investigating the effect of W-3 polyunsaturated fatty acids on serum albumin in patients with acute heart failure and hypoalbu…
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: Electronic Repositioning With Acuity and Easytrak Leads [NA]
A completed heart failure clinical trial investigating electronic repositioning with Acuity and Easytrak leads; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Antiremodeling Effect Of Aldosterone Receptors Blockade With Canrenone In Mild Chronic Heart Failure. AREA IN-CHF Study [Phase 3]
Phase 3 trial update on canrenone (aldosterone receptor blocker) for mild chronic heart failure shows results from the AREA IN-CHF study.
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: HCV Positive Heart Donors [Phase 4]
Phase 4 clinical trial update on heart failure using HCV-positive donors; results completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Cardiac Safety Study in Patients With HER2 + Breast Cancer [Phase 2]
A Phase 2 cardiac safety trial in HER2-positive breast cancer evaluated left ventricular function outcomes.
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Demonstration of Reverse Remodeling Effects of Entresto. Using Echocardiography Endocardial Surface Analysis [Phase 4]
Phase 4 trial update assessing reverse remodeling effects of Entresto using echocardiography endocardial surface analysis.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function [Phase 1]
Phase 1 study assessing safety, tolerability, and pharmacokinetics of AMG 986 in healthy volunteers and those with severe renal impairment; …
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FDA approval · 2021-01-27FDA Approved: FUROSEMIDE — Original Application (Sagent Pharmaceuticals)
FDA approved a new generic version of furosemide from Sagent Pharmaceuticals under an original application, enabling market entry as a loop …
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Effects of APIXaban on BRAIN Protection in Patients With Sinus Rhythm and Heart Failure: APIXBRAIN-HF Trial [Phase 2]
Phase 2 trial investigating the effects of APIXaban on brain protection in patients with heart failure and sinus rhythm.
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: Stem Cell Therapy in IschEmic Non-treatable Cardiac Disease [Phase 2]
Phase 2 clinical trial update for stem cell therapy in ischemic, non-treatable heart failure.
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FDA approval · 2021-01-13FDA Approved: BIDIL — Supplemental Application (Azurity Pharmaceuticals, Inc.)
FDA approved a supplemental application for BIDIL (hydralazine hydrochloride and isosorbide dinitrate) submitted by Azurity Pharmaceuticals,…
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CLINICAL_TRIALS trial_result · 2021-01-11Clinical Trial Update: Vitamin C Supplementation Intervention [NA]
A completed clinical trial investigating vitamin C supplementation in patients with heart failure; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Exogenous Ketones for Acutely Decompensated HEart Failure [Phase 3]
Phase 3 clinical trial evaluating exogenous ketones for acutely decompensated heart failure with low cardiac output; status and results are …
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Study on the Clinical and Mechanism of Wenyang Huoxue Decoction in Treating Heart Failure After Myocardial Infarction [Phase 2]
Phase 2 trial update exploring Wenyang Huoxue Decoction for heart failure following myocardial infarction.
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: A Prospective Evaluation of Natriuretic Peptide Based Referral of CHF Patients in Primary Care [NA]
A completed clinical trial evaluating natriuretic peptide–based referral of chronic heart failure patients in primary care; results posted i…
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CLINICAL_TRIALS trial_result · 2020-12-31Clinical Trial Update: OUTpatient Intravenous LASix Trial in Reducing Hospitalization for Acute Decompensated Heart Failure [Phase 4]
Phase 4 trial update evaluating outpatient intravenous furosemide (Lasix) to reduce hospitalization for acute decompensated heart failure ha…
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CLINICAL_TRIALS trial_result · 2020-12-24Clinical Trial Update: Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failure [Phase 1, Phase 2]
A randomized, double-blind, placebo-controlled study evaluating ITI-214 for safety and tolerability in patients with systolic heart failure …
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FDA approval · 2020-12-22FDA Approved: FUROSEMIDE — Supplemental Application (Marlex Pharmaceuticals, Inc.)
The FDA approved a supplemental application for furosemide from Marlex Pharmaceuticals, Inc., indicating an additional/or updated approval f…
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: The Purpose of This Study is to Determine if Eplerenone is Effective in Treatment of Mild to Moderate Heart Failure [Phase 4]
A Phase 4 trial update assessing whether eplerenone is effective in treating mild to moderate heart failure has completed.
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluated supplementation with glutamine and fish oil versus placebo in patients with heart failure; results post…
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Safety/Tolerability, Pharmacokinetics/Pharmacodynamics (PK/PD) of LCZ696 in Patients With Stable Heart Failure [Phase 2]
Phase 2 clinical trial assessing safety, tolerability, and PK/PD of LCZ696 in patients with stable heart failure has completed.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Renal Hemodynamic Effects of RLX030A in Subjects With Chronic Heart Failure (CHF) [Phase 2]
Phase 2 clinical trial update evaluating the renal hemodynamic effects of RLX030A in subjects with chronic heart failure has been completed.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Effect of Vildagliptin on Left Ventricular Function in Patients With Type 2 Diabetes and Congestive Heart Failure [Phase 4]
A Phase 4 trial evaluating the effect of vildagliptin on left ventricular function in patients with type 2 diabetes and congestive heart fai…