Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2020-10-07FDA Approved: DIGOXIN — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for digoxin submitted by Hikma Pharmaceuticals USA Inc., authorizing changes to the product as r…
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CLINICAL_TRIALS trial_result · 2020-10-05Clinical Trial Update: The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement [Phase 4]
Phase 4 trial evaluating the effectiveness and safety of levosimendan in patients with severe aortic stenosis and heart failure undergoing t…
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CLINICAL_TRIALS trial_result · 2020-09-28Clinical Trial Update: Analysing the Effect of Empagliflozin on Reduction of Tissue Sodium Content in Patients With Chronic Heart Failure [Phase 2]
Phase 2 trial update analyzing empagliflozin’s effect on tissue sodium content in chronic heart failure patients has completed.
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Studies of Empagliflozin and Its Cardiovascular, Renal and Metabolic Effects [Phase 4]
Phase 4 trial update on empagliflozin assessing cardiovascular, renal, and metabolic effects in heart failure and diabetes mellitus.
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FDA approval · 2020-09-17FDA Approved: LISINOPRIL — Supplemental Application (Exelan Pharmaceuticals Inc.)
The FDA approved a supplemental application for lisinopril by Exelan Pharmaceuticals Inc., related to a generic lisinopril product. This ref…
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes [Phase 4]
Phase 4 trial assessing the influence of metformin on the clinical course of chronic heart failure in patients with prediabetes.
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FDA approval · 2020-09-15FDA Approved: LISINOPRIL — Original Application (Chartwell RX, LLC)
FDA approves Chartwell RX, LLC's generic lisinopril (LISINOPRIL) under an original ANDA for the same indications as the brand. Indications i…
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CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Mandibular Advancement Device for Treatment of Obstructive Sleep Apnea and Its Impact on Cardiac Remodeling [Phase 2, Phase 3]
A clinical trial update on a mandibular advancement device for obstructive sleep apnea and its effects on cardiac remodeling, currently in P…
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes) [NA]
A pilot trial evaluating metformin therapy in heart failure patients with diabetes or prediabetes; study status is completed with results po…
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Management of Diabetes With Metformin In Patients With Chronic Heart Failure [NA]
A completed clinical trial evaluating metformin management in patients with chronic heart failure and diabetes; results posted in 2020.
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FDA approval · 2020-09-03FDA Approved: MILRINONE LACTATE — Original Application (Eugia US LLC)
FDA approved Eugia US LLC's milrinone lactate injection in 5% dextrose as a generic injectable under an Original Application (ANDA 209666) f…
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CLINICAL_TRIALS trial_result · 2020-08-31Clinical Trial Update: LifeVest Trends Validation Protocol
Clinical trial update for the LifeVest validation protocol completed; results posted in 2020.
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FDA approval · 2020-08-20FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Hydrochlorothiazide from Aurobindo Pharma Limited. The decision updates the approved generic pro…
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FDA approval · 2020-08-20FDA Approved: VASERETIC — Supplemental Application (Bausch Health US, LLC)
The FDA approved a supplemental application for VASERETIC (enalapril maleate and hydrochlorothiazide) from Bausch Health US, LLC.
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FDA approval · 2020-08-20FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for hydrochlorothiazide from Accord Healthcare Inc., approving changes under the supplemental submis…
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CLINICAL_TRIALS trial_result · 2020-08-19Clinical Trial Update: Evaluate the Safety and Efficacy of 48-Hour Infusions of HNO (Nitroxyl) Donor in Hospitalized Patients With Heart Failure [Phase 2]
Phase 2 clinical trial evaluating 48-hour infusions of an HNO donor for safety and efficacy in hospitalized heart failure patients has compl…
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CLINICAL_TRIALS trial_result · 2020-08-19Clinical Trial Update: Nutritional Therapy Interventions in Heart Failure [NA]
Clinical trial update on nutritional therapy interventions for heart failure (NYHA Class II) completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study [Phase 3]
Phase 3 randomized trial evaluating early sequential nephron blockade in acute heart failure patients, with acute kidney injury as a conditi…
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CLINICAL_TRIALS trial_result · 2020-08-14Clinical Trial Update: CardioMEMS European Monitoring Study for Heart Failure [NA]
A completed European Monitoring Study for the CardioMEMS system in heart failure with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-08-14Clinical Trial Update: Left Ventricular Synchronous Versus Sequential MultiSpot Pacing for Cardiac Resynchronization Therapy (CRT) [NA]
Clinical trial comparing left ventricular synchronous versus sequential MultiSpot pacing for cardiac resynchronization therapy completed wit…
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CLINICAL_TRIALS trial_result · 2020-08-13Clinical Trial Update: Patient and Family Partners in Heart Failure Care: Pilot Test of a Pre-visit Question Prompt List to Enhance Engagement During Medical Visits [NA]
This completed UNC-Chapel Hill pilot study tested a pre-visit question prompt list to boost patient and family engagement during heart failu…
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CLINICAL_TRIALS trial_result · 2020-08-13Clinical Trial Update: Stem Cells Therapy in Advanced Heart Failure [Phase 4]
A Phase 4 clinical trial update on stem cell therapy for advanced heart failure is reported with unknown status.
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CLINICAL_TRIALS research · 2020-08-06Clinical Trial Update: Evaluation of the Safety and Effectiveness of the OPTIMIZER System in Subjects With Heart Failure: FIX-HF-5 [NA]
Clinical trial update for the OPTIMIZER system evaluating safety and effectiveness in heart failure patients; study completed with results p…
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CLINICAL_TRIALS trial_result · 2020-08-04Clinical Trial Update: Reducing Heart Failure Re-admissions by Enhancing Sleep Apnea Treatment Adherence [NA]
A completed clinical trial from University of Pennsylvania evaluating whether improving sleep apnea treatment adherence reduces readmissions…
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Quartet Lead and Resynchronization Therapy Options III (QUARTO_III) [NA]
Completed clinical trial QUARTO III investigating lead and resynchronization therapy options for heart failure; results posted in 2020.