Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-08-22Clinical Trial Update: ECG Belt to Assess Electrical Synchronization [NA]
A completed clinical trial evaluating an ECG belt device to assess electrical synchronization in patients with bradycardia and heart failure…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Chronic Heart Failure: Cardiovascular Effects [Phase 2]
Phase 2 clinical trial exploring modulation of circulating 3-hydroxybutyrate levels in chronic heart failure to assess cardiovascular effect…
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FDA approval · 2022-08-17FDA Approved: VALSARTAN — Supplemental Application (Jubilant Cadista Pharmacuticals Inc.)
The FDA approved a supplemental application for valsartan from Jubilant Cadista Pharmaceuticals Inc. This approval indicates regulatory auth…
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FDA approval · 2022-08-16FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (Ascend Laboratories, LLC)
The FDA approved Ascend Laboratories' supplemental application for metoprolol succinate ER tablets.
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CLINICAL_TRIALS trial_result · 2022-08-16Clinical Trial Update: Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy [Phase 2, Phase 3]
A clinical trial examining whether L-carnitine can prevent heart damage in breast cancer patients undergoing anthracycline chemotherapy; the…
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CLINICAL_TRIALS trial_result · 2022-08-10Clinical Trial Update: mHealth for Self-care of Heart Failure in Uganda [NA]
A completed clinical trial evaluating mHealth-enabled self-care for heart failure in Uganda; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-08-10Clinical Trial Update: A Trial of Telemonitoring in Adults With Heart Failure [NA]
Completed clinical trial of telemonitoring in adults with heart failure; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-08-10Clinical Trial Update: A Trial of Vitamin D Therapy in Patients With Heart Failure [NA]
Clinical trial update for vitamin D therapy in heart failure; trial completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: Study to Evaluate the Safety and Tolerability of AMG 986 in Healthy Volunteers and Heart Failure Patients [Phase 1]
Phase 1 study evaluating safety and tolerability of AMG 986 in healthy volunteers and heart failure patients; study terminated with results …
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FDA approval · 2022-08-04FDA Approved: BUMETANIDE — Original Application (Novadoz Pharmaceuticals LLC)
FDA approves the original ANDA for bumetanide (generic) by Novadoz Pharmaceuticals LLC for use in edema associated with congestive heart fai…
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CLINICAL_TRIALS trial_result · 2022-08-01Clinical Trial Update: Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1) [NA]
Completed pragmatic trial evaluating methods to improve communication about serious illness; results have been posted (2022-08-01).
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Effects of L-arginine on Myocardial Energetic Efficiency and Global Longitudinal Strain [Phase 4]
Phase 4 trial investigating the effects of L-arginine on myocardial energetic efficiency and global longitudinal strain in myocardial dysfun…
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CLINICAL_TRIALS trial_result · 2022-07-25Clinical Trial Update: Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure. [Phase 2, Phase 3]
APhase 2/3 trial evaluating LVAD combined with allogeneic mesenchymal stem cell implantation in end-stage heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2022-07-22Clinical Trial Update: IPS Differentiated Cardiomyocytes Vein Transplantation for Chronic Heart Failure [Phase 2, Phase 3]
A clinical trial update for IPS differentiated cardiomyocytes vein transplantation in chronic heart failure across Phase 2 and Phase 3 stage…
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FDA approval · 2022-07-21FDA Approved: VALSARTAN — Supplemental Application (Amneal Pharmaceuticals LLC)
FDA approved a supplemental application for VALSARTAN from Amneal Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2022-07-18Clinical Trial Update: Weight-Adjusted Dosing of 3-OHB in Patients With Chronic Heart Failure [Phase 2]
Phase 2 trial evaluating weight-adjusted dosing of 3-hydroxybutyrate (3-OHB) in patients with chronic heart failure.
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CLINICAL_TRIALS research · 2022-07-15Clinical Trial Update: Exercise Intolerance in Elderly Patients With HFpEF(Heart Failure With Preserved Ejection Fraction) [NA]
A completed clinical trial evaluating exercise intolerance in elderly patients with heart failure with preserved ejection fraction (HFpEF).
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CLINICAL_TRIALS trial_result · 2022-07-08Clinical Trial Update: A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillators [NA]
Clinical trial evaluating a shared decision support intervention for patients offered implantable cardioverter-defibrillators has completed …
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FDA approval · 2022-07-06FDA Approved: TRIAMTERENE — Original Application (Biocon Pharma Inc.)
The FDA approved Biocon Pharma Inc.'s original ANDA for Triamterene, granting generic approval to market Triamterene.
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FDA approval · 2022-06-30FDA Approved: RAMIPRIL — Supplemental Application (Zydus Lifesciences Limited)
FDA approved a supplemental application for ramipril submitted by Zydus Lifesciences Limited under ANDA078832.
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FDA approval · 2022-06-29FDA Approved: ENALAPRIL MALEATE — Original Application (Amneal Pharmaceuticals NY LLC)
FDA approves the original generic application for enalapril maleate (Enalapril) manufactured by Amneal Pharmaceuticals NY LLC.
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CLINICAL_TRIALS trial_result · 2022-06-27Clinical Trial Update: The Left Ventricular Assist Device (LVAD) Off or On Pump Implantation Study [NA]
A terminated clinical trial comparing off-pump versus on-pump implantation in LVAD patients; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: The Bio-Clinical Effects of the (Sacubitril-Valsartan) Combination on Patients With Chronic Heart Failure [Phase 4]
A Phase 4 clinical trial evaluating the effects of sacubitril-valsartan on patients with chronic heart failure has been completed.
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CLINICAL_TRIALS trial_result · 2022-06-21Clinical Trial Update: Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction [Phase 2]
Phase 2 trial update on vasodilator therapy for heart failure with preserved ejection fraction (HFpEF) has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: Right Ventricular Function and Exercise Capacity in Patients With Continuous-flow Left Ventricular Assist Devices [NA]
Completed clinical trial evaluating right ventricular function and exercise capacity in patients with continuous-flow left ventricular assis…