Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD " [Phase 2, Phase 3]
Clinical trial evaluating safety and efficacy of empagliflozin and sacubitril/valsartan for heart failure with reduced ejection fraction in …
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: Tailoring Pacemaker Output to Physiology in Chronic Heart Failure [Phase 3]
A Phase 3 clinical trial evaluating tailoring pacemaker output to patient physiology in chronic heart failure is in the pipeline with an unk…
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: A Pilot Study: Preventing Adverse Remodelling Following Pacemaker Implantation [Phase 2]
Phase 2 pilot study investigating strategies to prevent adverse remodeling after pacemaker implantation in heart failure patients.
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk [Phase 3]
Phase 3 trial evaluating sotagliflozin in type 2 diabetes with moderate renal impairment at cardiovascular risk; study terminated with poste…
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial) [Phase 3]
Phase 3 SOLOIST-WHF trial assessing sotagliflozin effects on cardiovascular events in adults with type 2 diabetes and post-worsening heart f…
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN [Phase 4]
Phase 4 trial update of intravenous iron treatment in patients with chronic heart failure and iron deficiency (IRONMAN).
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CLINICAL_TRIALS trial_result · 2022-10-26Clinical Trial Update: A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease. [Phase 2]
Phase IIa clinical trial of TSG-01 in chronic heart failure due to coronary heart disease has completed.
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CLINICAL_TRIALS trial_result · 2022-10-26Clinical Trial Update: Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support [Phase 3]
Phase 3 trial update on ivabradine for cardiogenic shock requiring inotropic support in heart failure patients.
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FDA approval · 2022-10-25FDA Approved: METOLAZONE — Original Application (Aarkish Pharmaceuticals NJ Inc.)
FDA approved the original application for metolazone from Aarkish Pharmaceuticals NJ Inc., granting clearance to manufacture and market a ge…
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FDA approval · 2022-10-24FDA Approved: METOLAZONE — Original Application (Ingenus Pharmaceuticals LLC)
FDA approves Metolazone via Original Application for a generic version by Ingenus Pharmaceuticals LLC. The approval supports its use for ede…
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CLINICAL_TRIALS trial_result · 2022-10-21Clinical Trial Update: MDT-1118 Japan DT Study [Phase 3]
Phase 3 clinical trial update for MDT-1118 in Japan for heart failure has completed.
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FDA approval · 2022-10-17FDA Approved: FUROSEMIDE — Original Application (Rising Pharma Holdings, Inc.)
The FDA approved Rising Pharma Holdings, Inc.'s original ANDA for furosemide, authorizing a generic version of this diuretic.
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CLINICAL_TRIALS trial_result · 2022-10-17Clinical Trial Update: Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults [NA]
Completed clinical trial evaluating passive heat therapy effects on oxygen consumption and cardiovascular fitness in adults with heart condi…
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CLINICAL_TRIALS trial_result · 2022-10-13Clinical Trial Update: Clinical Utility of Subcutaneous Furosemide in Patients Presenting With Early Signs of Fluid Overload [Phase 2, Phase 3]
Phase 2/3 trial evaluating subcutaneous furosemide for early fluid overload in heart failure was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2022-10-07Clinical Trial Update: Comparison of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes [Phase 3]
Phase 3 trial comparing eplerenone to spironolactone in heart failure patients with glucose intolerance or Type 2 diabetes completed.
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CLINICAL_TRIALS trial_result · 2022-10-06Clinical Trial Update: Comparison of Outcomes and Access to Care for Heart Failure Trial [Phase 3]
A Phase 3 clinical trial update comparing outcomes and access to care in heart failure patients has completed.
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CLINICAL_TRIALS trial_result · 2022-10-04Clinical Trial Update: Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure [Phase 3]
Phase 3 trial update assessing safety and efficacy of combining Loop diuretics with thiazide-type diuretics in patients with decompensated h…
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CLINICAL_TRIALS trial_result · 2022-09-29Clinical Trial Update: Biomarker Guided Therapies in Stage A/B Heart Failure [Phase 2]
Phase 2 trial update on biomarker-guided therapies in stage A/B heart failure with data completed and results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-09-29Clinical Trial Update: Daxor - Blood Volume Analysis [NA]
A completed clinical trial on blood volume analysis by Daxor (sponsor: Duke University) in heart failure patients with results posted in 202…
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CLINICAL_TRIALS trial_result · 2022-09-22Clinical Trial Update: Effect of Dapagliflozin on VT in Patients With Heart Failure. [Phase 4]
Phase 4 clinical trial exploring the effect of dapagliflozin on VT in patients with heart failure.
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CLINICAL_TRIALS trial_result · 2022-09-15Clinical Trial Update: Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure [Phase 2]
Phase 2 trial evaluating a genetically targeted therapy to prevent symptomatic atrial fibrillation in patients with heart failure; study com…
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CLINICAL_TRIALS trial_result · 2022-09-06Clinical Trial Update: Allogeneic Stem Cell Therapy in Heart Failure [Phase 2]
Phase 2 clinical trial update of allogeneic stem cell therapy in heart failure has completed.
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FDA approval · 2022-08-31FDA Approved: FUROSEMIDE — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for furosemide from Hospira, Inc.
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FDA approval · 2022-08-26FDA Approved: CHLORTHALIDONE CHLORTHALIDONE — Original Application (Alembic Pharmaceuticals Limited)
FDA approved an original application for a generic chlorthalidone by Alembic Pharmaceuticals Limited.
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CLINICAL_TRIALS trial_result · 2022-08-23Clinical Trial Update: Cardiac Resynchronization in the Elderly [NA]
Clinical trial update for cardiac resynchronization in elderly with heart failure; study completed with results posted in 2022.