Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure [Phase 3]
A Phase 3 clinical trial evaluating the effect of empagliflozin in patients hospitalized for acute heart failure has completed with results …
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CLINICAL_TRIALS trial_result · 2022-06-03Clinical Trial Update: Safety and Efficacy of Furosemide 40mg + Amiloride Hydrochloride 10mg to Reduct Edema [Phase 3]
Phase 3 trial updating safety and efficacy of furosemide 40mg plus amiloride hydrochloride 10mg for edema reduction in congestive heart fail…
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FDA approval · 2022-06-01FDA Approved: TOPROL XL — Supplemental Application (Melinta Therapeutics, LLC)
The FDA approved a supplemental application for TOPROL XL (metoprolol succinate) submitted by Melinta Therapeutics, LLC. This action updates…
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FDA approval · 2022-05-26FDA Approved: BUMETANIDE — Original Application (GLENMARK PHARMACEUTICALS INC., USA)
FDA approved Glenmark Pharmaceuticals USA's Original Application for bumetanide, authorizing the generic diuretic bumetanide for U.S. use.
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Scar Location and Acute Haemodynamic Response to MultiPoint Pacing Study in Patients With Ischemic Cardiomyopathy [NA]
Clinical trial update for a multi-point pacing study in ischemic cardiomyopathy has been terminated with results posted.
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CLINICAL_TRIALS research · 2022-05-18Clinical Trial Update: Retrospective Experience Of CIED Implantation
A retrospective clinical trial update reviewing outcomes of cardiac implantable electronic device implantation.
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: A Digital Flu Intervention for People With Cardiovascular Conditions [NA]
A completed clinical trial evaluating a digital flu intervention for people with cardiovascular conditions, with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: Tolvaptan For Worsening Outpatient Heart Failure: Role of Copeptin In Identifying Responders [Phase 4]
Phase 4 trial evaluating tolvaptan for worsening outpatient heart failure and the role of copeptin in identifying responders; completed with…
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CLINICAL_TRIALS trial_result · 2022-04-20Clinical Trial Update: Biomarker Study: Heart Failure Patients at Risk [Phase 1, Phase 2]
Phase 1/2 biomarker study in heart failure patients at risk, status currently unknown.
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CLINICAL_TRIALS trial_result · 2022-04-18Clinical Trial Update: A Trial to Study BAY1753011 in Patients With Congestive Heart Failure [Phase 2]
Phase 2 trial investigating BAY1753011 in patients with congestive heart failure has completed.
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FDA approval · 2022-04-12FDA Approved: FUROSEMIDE — Supplemental Application (Phlow Corporation)
FDA granted a supplemental approval for Furosemide by Phlow Corporation under the existing NDA; the snippet does not specify the exact natur…
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CLINICAL_TRIALS trial_result · 2022-04-08Clinical Trial Update: Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure. [Phase 4]
Phase 4 clinical trial update investigating nocturnal oxygen needs and central sleep apnea in patients with chronic heart failure.
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FDA approval · 2022-04-06FDA Approved: ISOSORBIDE DINITRATE AND HYDRALAZINE HYDROCHLORIDE — Original Application (Ingenus Pharmaceuticals, LLC)
FDA approved Ingenus Pharmaceuticals' original application (ANDA 215586) for Isosorbide Dinitrate and Hydralazine Hydrochloride. The product…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Strategic Management to Optimize Response To Cardiac Resynchronization Therapy [NA]
A completed clinical trial evaluating strategic management to optimize response to cardiac resynchronization therapy in heart failure patien…
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Deployment of American Heart Association Heart Failure Protocols and Content Within the Intel® Health Guide System [NA]
Completed clinical trial evaluating deployment of American Heart Association heart failure protocols within the Intel Health Guide system.
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FDA approval · 2022-03-31FDA Approved: QUINAPRIL — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for a quinapril hydrochloride generic product manufactured by Aurobindo Pharma Limited.
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FDA approval · 2022-03-30FDA Approved: ENALAPRIL MALEATE ORAL SOLUTION — Original Application (Ascend Laboratories, LLC)
The FDA approved Ascend Laboratories' enalapril maleate oral solution as an original generic application for enalapril; the drug is used to …
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: Intervention With Vitamin D and Omega-3 Supplements and Incident Heart Failure [Phase 3]
Phase 3 trial update on intervention with Vitamin D and Omega-3 supplements in heart failure.
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: Liberal Versus Restrictive Use of Dobutamine in Cardiac Surgery [Phase 3]
Phase 3 trial updating to compare liberal versus restrictive use of dobutamine in cardiac surgery.
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CLINICAL_TRIALS trial_result · 2022-03-15Clinical Trial Update: Weight-Based Torsemide Dosing in Subjects With Heart Failure [Phase 4]
Phase 4 clinical trial examining weight-based dosing of torsemide in heart failure patients has completed.
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FDA approval · 2022-03-11FDA Approved: DIGOXIN — Original Application (Amici Pharma, Inc)
FDA approved the original ANDA for digoxin from Amici Pharma, authorizing a generic digoxin product.
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CLINICAL_TRIALS trial_result · 2022-03-09Clinical Trial Update: Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization [NA]
A terminated clinical trial evaluating QRS frequency at different left ventricular pacing sites for cardiac resynchronization therapy; resul…
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Bioprofiling Response to Mineralocorticoid Receptor Antagonists for the Prevention of Heart Failure [Phase 2]
Phase 2 trial update on bioprofiling response to mineralocorticoid receptor antagonists for prevention of heart failure.
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CLINICAL_TRIALS trial_result · 2022-03-03Clinical Trial Update: CoQ10 and D-ribose in Patients With Diastolic Heart Failure [Phase 2]
Phase 2 trial evaluating CoQ10 and D-ribose in diastolic heart failure completed with posted results.
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FDA approval · 2022-02-25FDA Approved: TRIAMTERENE AND HYDROCHLOROTHIAZIDE — Supplemental Application (BluePoint Laboratories)
The FDA approved a supplemental application for Triamterene and Hydrochlorothiazide from BluePoint Laboratories, enabling the marketing of t…