Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2023-02-17FDA Approved: SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for the generic Spironolactone and Hydrochlorothiazide from Mylan Pharmaceuticals Inc., a combinatio…
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CLINICAL_TRIALS trial_result · 2023-02-16Clinical Trial Update: The CASCADE HF Soft Launch and Calibration Phase I and II [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial update for CASCADE HF, with results posted in 2023, focusing on heart failure.
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CLINICAL_TRIALS trial_result · 2023-02-10Clinical Trial Update: Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure [Phase 2, Phase 3]
Clinical trial assessing safety, tolerability, PK/PD of LCZ696 in pediatric heart failure, followed by a 52-week double-blind comparison wit…
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CLINICAL_TRIALS trial_result · 2023-02-10Clinical Trial Update: Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the dose response of inorganic nitrate on exercise performance in patients with heart failure; the study…
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CLINICAL_TRIALS trial_result · 2023-02-10Clinical Trial Update: Stepped Care for Depression in Heart Failure [NA]
A completed clinical trial evaluating stepped care for depression in patients with heart failure; results posted in 2023.
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CLINICAL_TRIALS research · 2023-02-09Clinical Trial Update: Insomnia Self-Management in Heart Failure [NA]
Clinical trial update on insomnia self-management in heart failure; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-02-03Clinical Trial Update: ECG Belt for CRT Response [NA]
Clinical trial update for an ECG belt intended to assess CRT response in heart failure; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: SODIUM-HF: Study of Dietary Intervention Under 100 MMOL in Heart Failure [Phase 3]
Phase 3 trial update for a dietary sodium intervention (under 100 mmol) in heart failure has completed.
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FDA approval · 2023-01-27FDA Approved: CAPTOPRIL — Original Application (AiPing Pharmaceutical, Inc.)
The FDA approved AiPing Pharmaceutical’s Original Application for CAPTOPRIL (captopril), a generic ACE inhibitor. The approval supports indi…
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CLINICAL_TRIALS trial_result · 2023-01-25Clinical Trial Update: Oxygen Versus PAP for Sleep Apnea in Heart Failure [Phase 4]
Phase 4 trial comparing oxygen therapy to positive airway pressure for sleep apnea in heart failure; results posted.
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FDA approval · 2023-01-23FDA Approved: MILRINONE LACTATE — Original Application (Shandong New Time Pharmaceutical Co., Ltd.)
FDA approved the original application for milrinone lactate (generic) from Shandong New Time Pharmaceutical Co., Ltd. under ANDA216373. The …
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CLINICAL_TRIALS trial_result · 2023-01-20Clinical Trial Update: Study of the Safety and Efficacy of Roxadustat in the Treatment of Heart Failure With Chronic Kidney Disease and Anemia [Phase 4]
Phase 4 trial update evaluating the safety and efficacy of Roxadustat for heart failure with chronic kidney disease and anemia.
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CLINICAL_TRIALS trial_result · 2023-01-12Clinical Trial Update: A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure [Phase 3]
This update reports results from a Phase 3 study evaluating the impact of canagliflozin on health status, quality of life, and functional st…
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CLINICAL_TRIALS trial_result · 2022-12-23Clinical Trial Update: EMPAGUM: Effects of Empagliflozin on Gut Microbiota in Heart Failure With a Preserved Ejection Fraction [Phase 4]
Phase 4 trial evaluating the effects of empagliflozin on gut microbiota in patients with heart failure with preserved ejection fraction.
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CLINICAL_TRIALS trial_result · 2022-12-23Clinical Trial Update: Relationship Between LINQ™ Subcutaneous Impedance and Right-sided Hemodynamic Measurements [NA]
A completed clinical trial evaluating the relationship between LINQ subcutaneous impedance and right-sided hemodynamic measurements in heart…
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CLINICAL_TRIALS trial_result · 2022-12-23Clinical Trial Update: Evaluating Efficacy of Digital Health Technology in the Treatment of Congestive Heart Failure [NA]
A completed clinical trial evaluating the efficacy of a digital health technology in treating congestive heart failure; results posted in 20…
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FDA approval · 2022-12-21FDA Approved: DOBUTAMINE — Original Application (Slate Run Pharmaceuticals)
FDA approves Slate Run Pharmaceuticals' dobutamine—Original Application (ANDA 216131)—granting approval of a generic dobutamine product. Thi…
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FDA approval · 2022-12-19FDA Approved: SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Prasco Laboratories)
FDA approves a supplemental application for the combination product spironolactone and hydrochlorothiazide, manufactured by Prasco Laborator…
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FDA approval · 2022-12-16FDA Approved: FUROSEMIDE — Original Application (Lifestar Pharma LLC)
FDA approved Lifestar Pharma LLC's original application for furosemide, authorizing the generic version of the diuretic for its labeled indi…
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CLINICAL_TRIALS trial_result · 2022-12-12Clinical Trial Update: Lavare Cycle in Patients Receiving HeartWare Left Ventricular Assist Device [NA]
Clinical trial update for Lavare Cycle in patients with HeartWare LVAD; study terminated with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-12-09Clinical Trial Update: Retrograde Application of Bone Marrow Aspirate Concentrate [Phase 2]
A Phase 2 clinical trial evaluating retrograde application of bone marrow aspirate concentrate for heart failure has completed.
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CLINICAL_TRIALS trial_result · 2022-12-07Clinical Trial Update: Sodium-glucose Cotransporter Type 2 Inhibitors for Acute Cardiorenal Syndrome Prevention [Phase 4]
Phase 4 trial update evaluating SGLT2 inhibitors for prevention of acute cardiorenal syndrome in congestive heart failure.
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CLINICAL_TRIALS trial_result · 2022-12-02Clinical Trial Update: Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure [Phase 2, Phase 3]
Phase 2/3 crossover trial assessing pharmacokinetics and bioavailability of a subcutaneous versus intravenous furosemide regimen in chronic …
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CLINICAL_TRIALS trial_result · 2022-11-21Clinical Trial Update: Dapagliflozin Effect on Rheumatic Mitral Stenosis [Phase 3]
Phase 3 trial evaluating dapagliflozin for rheumatic mitral stenosis in patients with rheumatic heart disease and heart failure.
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FDA approval · 2022-11-02FDA Approved: LANOXIN — Supplemental Application (Covis Pharma US, Inc)
The FDA approved a supplemental application for LANOXIN (digoxin) submitted by Covis Pharma US, Inc. This approval covers the changes reques…