Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2023-05-05FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (Zydus Pharmaceuticals (USA) Inc.)
FDA approved a supplemental application for metoprolol succinate from Zydus Pharmaceuticals (USA) Inc., approving its generic product under …
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MI [Phase 3]
Phase 3 trial comparing sacubitril/valsartan to valsartan on left ventricular remodeling in asymptomatic LV systolic dysfunction after myoca…
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FDA approval · 2023-04-20FDA Approved: SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for Spironolactone and Hydrochlorothiazide by Mylan Pharmaceuticals Inc., potentially updating label…
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: Diabetes and Lipid Accumulationand Heart Transplant
A completed clinical trial listing for diabetes mellitus and heart failure conditions; results posted in 2023.
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FDA approval · 2023-04-14FDA Approved: KAPSPARGO — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approves a supplemental application for KAPSPARGO (metoprolol succinate) by Sun Pharmaceutical Industries.
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment [Phase 4]
Phase 4 clinical trial update assessing hepato-renal regulation of water conservation in heart failure patients treated with an SGLT-2 inhib…
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CLINICAL_TRIALS withdrawal · 2023-04-12Clinical Trial Update: Comparing Diuretic Strategies in Hospitalized Heart Failure [Phase 4]
A Phase 4 trial comparing diuretic strategies in hospitalized heart failure was withdrawn.
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: IV Iron in Acute Decompensated Heart Failure [Phase 4]
A Phase 4 clinical trial update on intravenous iron in acute decompensated heart failure has completed, providing post-marketing surveillanc…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance [Phase 3]
A Phase 3 clinical trial comparing DAPAgliflozin to a thiazide diuretic in patients with heart failure and diuretic resistance. Status is cu…
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CLINICAL_TRIALS trial_result · 2023-04-06Clinical Trial Update: Dexamethasone Versus Prednisone in Heart Failure Patients, Hospitalized With Exacerbation of Chronic Obstructive Pulmonary Disease. [Phase 4]
Phase 4 trial update comparing dexamethasone to prednisone in hospitalized chronic obstructive pulmonary disease patients with heart failure…
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure [NA]
A completed clinical trial evaluating pacemakers for treating slow heart rate in heart failure patients, including those with preserved ejec…
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FDA approval · 2023-04-04FDA Approved: ACETAZOLAMIDE — Original Application (Zydus Lifesciences Limited)
FDA approved a generic acetazolamide product from Zydus Lifesciences Limited under an Original Application (ANDA211069).
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: The Persistence of Autoantibody Neutralisation by BC 007 in Patients With Chronic HFrEF and Autoantibodies Against the Beta1-Adrenergic Receptor [Phase 2]
Phase 2 trial update assessing persistence of autoantibody neutralization by BC 007 in patients with chronic heart failure and beta1-adrener…
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Dapagliflozin at Discharge on Hospital Heart Failure Readmission [Phase 4]
This Phase 4 trial evaluates whether starting dapagliflozin at hospital discharge reduces heart failure readmissions in patients with heart …
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CLINICAL_TRIALS trial_result · 2023-03-28Clinical Trial Update: Clinical Study of Endocardial Myocardial Biopsy [Phase 4]
A Phase 4 clinical trial is ongoing to evaluate endocardial myocardial biopsy in patients with myocarditis and cardiomyopathies.
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: Screening for Advanced Heart Failure IN Stable outPatientS - The SAINTS Study (SAINTS B) [Phase 4]
Phase 4 clinical trial update for the SAINTS B study evaluating screening in advanced heart failure patients with reduced ejection fraction;…
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FDA approval · 2023-03-17FDA Approved: LISINOPRIL AND HYDROCHLOROTHIAZIDE — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved a supplemental application for the Lisinopril and Hydrochlorothiazide combination from Lupin Pharmaceuticals, formalizing an ap…
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CLINICAL_TRIALS trial_result · 2023-03-17Clinical Trial Update: Sacubitril/Valsartan for CKD5 Stage Dialysis Patients [Phase 4]
A Phase 4 clinical trial update on sacubitril/valsartan in patients with CKD stage 5 on dialysis and heart failure has completed.
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FDA approval · 2023-03-16FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved a supplemental application for Hydrochlorothiazide submitted by Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals In…
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: PVP-Guided Decongestive Therapy in HF [Phase 4]
Phase 4 clinical trial update on PVP-guided decongestive therapy for heart failure and edema shows ongoing status.
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study [Phase 4]
A Phase 4 pilot trial comparing flexible versus fixed diuretic regimens for chronic heart failure management.
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FDA approval · 2023-03-10FDA Approved: TOPROL XL — Supplemental Application (Melinta Therapeutics, LLC)
The FDA approved a supplemental application for Toprol XL (metoprolol succinate) submitted by Melinta Therapeutics, LLC.
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FDA approval · 2023-02-27FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (Actavis Pharma, Inc.)
FDA approved a supplemental application for metoprolol succinate from Actavis Pharma, Inc., authorizing a generic extended-release metoprolo…
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CLINICAL_TRIALS trial_result · 2023-02-24Clinical Trial Update: Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND) [Phase 3]
Phase 3 clinical trial DIAMOND evaluating patiromer for managing hyperkalemia in patients on RAAS inhibitors for heart failure has completed…
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CLINICAL_TRIALS trial_result · 2023-02-24Clinical Trial Update: Furoscix Real-World Evaluation for Decreasing Hospital Admissions in Heart Failure [Phase 3]
Phase 3 clinical trial update evaluating Furoscix for reducing hospital admissions in heart failure, with completed status and posted result…