Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2023-07-21FDA Approved: TORSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved Hikma Pharmaceuticals USA Inc.'s supplemental application for torsemide, granting approval of a generic torsemide product u…
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Efficacy of Metformin as add-on Therapy in Non-Diabetic Heart Failure Patients [Phase 4]
Phase 4 trial evaluating metformin as add-on therapy in non-diabetic patients with heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-07-12Clinical Trial Update: Impact on Atrial Remodeling of Dapaglifozin in Patients With Heart Failure . [Phase 3]
Phase 3 trial evaluating the impact of dapagliflozin on atrial remodeling in patients with heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-07-05Clinical Trial Update: Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency [Phase 2]
Phase 2 clinical trial evaluating ferric carboxymaltose to improve skeletal muscle metabolism in heart failure patients with functional iron…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Impact of Beta-blockers on Physical Function in HFpEF [Phase 4]
Phase 4 trial update evaluating the impact of beta-blockers on physical function in heart failure with preserved ejection fraction (HFpEF); …
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: REALIsM-HF Pilot Study [NA]
Pilot study update for REALIsM-HF (NCT03507439) in heart failure; trial completed with results posted in 2023.
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FDA approval · 2023-06-28FDA Approved: SPIRONOLACTONE — Supplemental Application (Amneal Pharmaceuticals LLC)
The FDA approved a supplemental application for Spironolactone from Amneal Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Sacubitril/Valsartan Versus Valsartan in Heart Failure [Phase 4]
Phase 4 trial comparing sacubitril/valsartan to valsartan in heart failure has completed.
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CLINICAL_TRIALS withdrawal · 2023-06-26Clinical Trial Update: Evaluation of Sildenafil for the Treatment of Moderate Congestive Heart Failure [Phase 4]
A Phase 4 clinical trial evaluating sildenafil for moderate congestive heart failure was withdrawn.
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FDA approval · 2023-06-23FDA Approved: SPIRONOLACTONE — Supplemental Application (Oxford Pharmaceuticals, LLC)
FDA approved a supplemental application for spironolactone by Oxford Pharmaceuticals, LLC. The approval allows continued marketing of the ge…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI [Phase 3]
Phase 3 trial comparing ARNI versus ACE inhibitor to determine superiority in reducing heart failure events after acute myocardial infarctio…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Values-Affirmation Intervention Targeting Medication Adherence in Older Adults With Heart Failure [NA]
A completed clinical trial evaluating a values-affirmation intervention to improve medication adherence in older adults with heart failure; …
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III) [Phase 2]
Phase 2 clinical trial updating results for splanchnic nerve block as a therapy for chronic heart failure.
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FDA approval · 2023-06-12FDA Approved: METOPROLOL SUCCINATE — Original Application (Granules Pharmaceuticals Inc.)
FDA approved the Original Application (ANDA216916) for Metoprolol succinate, a generic version manufactured by Granules Pharmaceuticals Inc.
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FDA approval · 2023-06-07FDA Approved: CANDESARTAN — Supplemental Application (Macleods Pharmaceuticals Limited)
FDA approved a supplemental application for candesartan by Macleods Pharmaceuticals Limited, enabling the marketed generic candesartan produ…
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FDA label_change · 2023-06-07FDA Approved: LOSARTAN POTASSIUM — Supplemental Application (Macleods Pharmaceuticals Limited)
FDA supplemental application for Losartan Potassium by Macleods Pharmaceuticals Limited, likely involving labeling changes for the generic d…
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FDA approval · 2023-06-05FDA Approved: DEFINITY — Supplemental Application (Lantheus Medical Imaging, Inc.)
FDA approved a supplemental application for DEFINITY (perflutren) submitted by Lantheus Medical Imaging, Inc.
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: Building Strength Through Rehabilitation for Heart Failure Patients (BISTRO-STUDY) [NA]
A terminated clinical trial investigating rehabilitation to improve outcomes in heart failure patients; results posted in 2023.
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FDA approval · 2023-05-26FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (BluePoint Laboratories)
The FDA approved a supplemental application for metoprolol succinate from BluePoint Laboratories, allowing continued manufacture of the gene…
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FDA approval · 2023-05-17FDA Approved: SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for Sun Pharmaceutical's spironolactone and hydrochlorothiazide combination product. The submission …
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CLINICAL_TRIALS trial_result · 2023-05-17Clinical Trial Update: MOre REsponse on Cardiac Resynchronization Therapy With MultiPoint Pacing [NA]
A terminated clinical trial examining MultiPoint Pacing for Cardiac Resynchronization Therapy in heart failure; results posted but no curren…
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FDA approval · 2023-05-10FDA Approved: FUROSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for furosemide submitted by Hikma Pharmaceuticals USA Inc.
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: LSFG-SKIN, Laser Speckle Flowgraphy [NA]
Clinical trial LSFG-SKIN using Laser Speckle Flowgraphy was terminated; no results posted beyond status update.
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FDA approval · 2023-05-09FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (Quallent Pharmaceuticals Health LLC)
The FDA approved a supplemental application for a generic Metoprolol Succinate product from Quallent Pharmaceuticals Health LLC.
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CLINICAL_TRIALS withdrawal · 2023-05-06Clinical Trial Update: Sacubitril-valsartan Versus Usual Anti-hypertensives in LVAD [Phase 4]
A Phase 4 trial comparing sacubitril-valsartan to usual antihypertensives in patients with congestive heart failure and hypertension has bee…