Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-05-06Clinical Trial Update: Finding Early Predictors of Myocardial Dysfunction
This document reports the completion of a clinical trial investigating early predictors of myocardial dysfunction in people with hypertensio…
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CLINICAL_TRIALS trial_result · 2014-05-06Clinical Trial Update: Strategies for Aggressive Central Afterload Reduction in Patients With Heart Failure [NA]
The Mayo Clinic-sponsored trial update reports completed results on aggressive central afterload reduction in patients with heart failure.
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CLINICAL_TRIALS research · 2014-05-05Clinical Trial Update: Clinical Performance Evaluation of AQT90 FLEX BNP and NT-proBNP
Clinical performance evaluation of the AQT90 FLEX BNP and NT-proBNP assays has been completed. The study targeted heart failure patients.
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure [Phase 2]
Phase 2 safety and efficacy study of Conivaptan (YM087) in patients with acute decompensated heart failure has completed. The trial status i…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure [Phase 2]
Phase 2 safety study comparing GE-145 320 mg/mL injection to iopamidol 370 mg/mL in elderly undergoing coronary procedure; study completed w…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Evaluation of the HeartWare Left Ventricular Assist Device for the Treatment of Advanced Heart Failure [NA]
A completed clinical trial evaluated the HeartWare Left Ventricular Assist Device for advanced chronic heart failure, with results posted in…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Biventricular Pacing After Cardiopulmonary Bypass [NA]
Clinical trial update on biventricular pacing after cardiopulmonary bypass for heart failure; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Sunitinib and Atrial Trabeculae Contractility
This completed clinical trial evaluated the effect of sunitinib on atrial trabeculae contractility with focus on cardiotoxicity, ischemia, a…
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CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: MADIT ASIA Cardiac Resynchronization Trial [Phase 3]
The Phase 3 MADIT ASIA Cardiac Resynchronization Trial sponsored by Boston Scientific was terminated; it enrolled patients with congestive h…
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CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity
This completed clinical trial evaluates whether myocardial deformation imaging can detect trastuzumab-induced cardiotoxicity associated with…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Evaluation of Acute Cardiogenic Dyspnoea With Thorax Echography and Pro-BNP in the Emergency Department
This update describes a completed clinical trial evaluating acute cardiogenic dyspnea using thorax echography and pro-BNP in the emergency d…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Cost Effectiveness and Quality of Life in Heart Failure Patients With Diabetes [NA]
This clinical trial update reports on cost-effectiveness and quality-of-life outcomes in heart failure patients with diabetes. The study sta…
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FDA approval · 2014-04-23FDA Approved: SPIRONOLACTONE — Original Application (Jubilant Cadista Pharmacuticals Inc.)
FDA approved the original ANDA for spironolactone, authorizing a generic version manufactured by Jubilant Cadista Pharmaceuticals Inc.
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Sodium Channel Splicing in Heart Failure Trial
The trial update reports the completion of a study on sodium channel splicing in heart failure and notes related conditions including atrial…
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CLINICAL_TRIALS trial_result · 2014-04-22Clinical Trial Update: Gulf Acute Heart Failure Registry
The Gulf Acute Heart Failure Registry sponsored by the Gulf Heart Association has completed its study. This update notes completion of data …
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT) [Phase 2, Phase 3]
Clinical trial update for EchoCRT (echocardiography-guided cardiac resynchronization therapy) shows termination after Phase 2/3 with posted …
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CLINICAL_TRIALS trial_result · 2014-04-14Clinical Trial Update: Evaluating the Relationship Between Fatty Acids and Heart Disease
A completed clinical trial update from Brigham and Women's Hospital investigates the relationship between fatty acids and cardiovascular dis…
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Nt-proBNP Versus Clinical Guided Discharge in Acute Heart Failure [Phase 4]
Phase 4 clinical trial update evaluating Nt-proBNP-guided discharge versus clinical-guided discharge in patients with acute heart failure.
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CLINICAL_TRIALS withdrawal · 2014-04-09Clinical Trial Update: A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies [Phase 2]
A Phase 2 study evaluating the pharmacokinetics and pharmacodynamics of JNJ-54452840 in heart failure patients with anti-beta1-adrenergic re…
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CLINICAL_TRIALS trial_result · 2014-04-08Clinical Trial Update: Next Generation INCEPTA Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy (CRT-D) Field Following Study
Update on the completed INCEPTA ICD/CRT-D study with results posted.
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Weight Loss as Treatment in Heart Disease [NA]
A completed clinical trial from the University of Copenhagen evaluated weight loss as a treatment for heart failure. The study identifier is…
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: Leadless Electrocardiogram (ECG) Evaluation Study [NA]
The study evaluating a leadless ECG device in patients with heart failure has completed, and results have been posted.
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CLINICAL_TRIALS research · 2014-03-31Clinical Trial Update: Renal Denervation in Patients With Heart Failure Secondary to Chagas Disease [NA]
Update on a renal denervation study in patients with heart failure caused by Chagas disease; the trial status is currently unknown.
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CLINICAL_TRIALS research · 2014-03-28Clinical Trial Update: ETIC (Therapeutic Education in Heart Failure) [NA]
An update on the ETIC trial (Therapeutic Education in Heart Failure) conducted by University Hospital, Clermont-Ferrand; the current status …
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CLINICAL_TRIALS withdrawal · 2014-03-27Clinical Trial Update: Bumetanide Versus Furosemide in Heart Failure [Phase 3]
A Phase 3 trial comparing bumetanide to furosemide in heart failure has been withdrawn.