Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Biventricular Versus Right Ventricular Pacing in Heart Failure Patients With Atrioventricular Block (BLOCK HF) [NA]
The BLOCK HF trial comparing biventricular pacing to right ventricular pacing in heart failure patients with atrioventricular block has comp…
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CLINICAL_TRIALS research · 2014-03-21Clinical Trial Update: Biomarkers and Therapeutic Modelisation in Heart Failure [NA]
This document provides an update on a clinical trial investigating biomarkers and therapeutic modelling in heart failure. The status and pha…
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CLINICAL_TRIALS research · 2014-03-20Clinical Trial Update: Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics. [Phase 4]
An investigator-initiated Phase 4 randomized open-label study comparing Britomar prolonged-release torasemide with Diuver torasemide to asse…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nesiritide (BNP) for improving heart, kidney, and hormonal function in people with reduced heart pumping f…
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Functional Electrical Stimulation in Cardiac Patients [NA]
A completed clinical trial evaluated functional electrical stimulation in cardiac patients. The study involved individuals with coronary art…
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: The Study to Evaluate Efficacy and Safety of Candesartan vs Losartan in Hypertension With Heart Failure (HONOR) [Phase 4]
The HONOR Phase 4 trial comparing candesartan to losartan in hypertension with heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: The Darlington Retrospective Outpatient Study
This clinical trial update notes the completion of the Darlington Retrospective Outpatient Study for heart failure with results posted in 20…
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CLINICAL_TRIALS withdrawal · 2014-03-13Clinical Trial Update: Angiotensin Converting Enzyme Inhibition in Children With Mitral Regurgitation [Phase 3]
Phase 3 trial evaluating ACE inhibition in children with mitral regurgitation was terminated.
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CLINICAL_TRIALS trial_result · 2014-03-12Clinical Trial Update: Exercise and Noninvasive Ventilation in Heart Failure Patients [NA]
The document reports the completion of a clinical trial evaluating exercise with noninvasive ventilation in heart failure patients.
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CLINICAL_TRIALS trial_result · 2014-03-07Clinical Trial Update: Prevalence of Asymptomatic Ventricular Dysfunction
A completed clinical trial update assessing the prevalence of asymptomatic ventricular dysfunction.
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FDA approval · 2014-03-06FDA Approved: SPIRONOLACTONE — Original Application (NorthStar Rx LLC)
The FDA approved NorthStar Rx LLC's Original Application for spironolactone (generic spironolactone).
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CLINICAL_TRIALS research · 2014-03-05Clinical Trial Update: China National Heart Failure Registry
Clinical trial registry update for the China National Heart Failure Registry, noting sponsor and disease focus with an unknown study status.
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CLINICAL_TRIALS research · 2014-03-05Clinical Trial Update: Evaluation of Cross-Linked Polyelectrolyte (CLP) With Placebo in Heart Failure Subjects [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating Cross-Linked Polyelectrolyte (CLP) versus placebo in patients with h…
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CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: An Open-label, One-arm, Study to Evaluate the Hemodynamic Changes and Safety of Nesiritide for Acute Decompensated Heart Failure [Phase 3]
An open-label, single-arm Phase 3 trial evaluating the hemodynamic effects and safety of Nesiritide in acute decompensated heart failure has…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Tissue Doppler Imaging (TDI) Versus Electrocardiography (ECG) Interventricular Pacing Delay Optimization in Cardiac Resynchronization Therapy (CRT) [Phase 3]
This update reports the completion of a Phase 3 trial comparing Tissue Doppler Imaging (TDI) versus ECG-based optimization for interventricu…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Noninvasive Ventilation and Thoracic-abdominal Kinematics in Heart Failure Patients [NA]
A completed clinical trial evaluating noninvasive ventilation and thoracic–abdominal kinematics in patients with heart failure.
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FDA approval · 2014-02-26FDA Approved: LISINOPRIL AND HYDROCHLOROTHIAZIDE — Supplemental Application (GSMS, Incorporated)
FDA approved a supplemental application for the generic fixed-dose combination of lisinopril and hydrochlorothiazide (GSMS, Incorporated).
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FDA approval · 2014-02-26FDA Approved: LISINOPRIL AND HYDROCHLOROTHIAZIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for a generic lisinopril and hydrochlorothiazide combination tablet from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: RAPID-RF: Remote Active Monitoring in Patients With Heart Failure
This update reports that the RAPID-RF remote active monitoring trial in heart failure sponsored by Boston Scientific has completed.
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Ventricular Matrix Remodeling: Correlates and Prognosis
This completed clinical trial update analyzes ventricular matrix remodeling and its relationship to prognosis in heart disease, identifying …
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CLINICAL_TRIALS research · 2014-02-20Clinical Trial Update: Mapping Novel Disease Genes for Dilated Cardiomyopathy
This clinical trial update describes Mayo Clinic-led efforts to map novel genes implicated in dilated cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Treatment of the lOw IGF-1 Syndrome aSsociated With Chronic Heart fAilure: A Randomized, Placebo-Controlled, Double-Blind Study. [Phase 2]
A Phase 2 randomized, placebo-controlled study evaluating treatment for low IGF-1 syndrome in chronic heart failure has been suspended.
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Growth Hormone Deficiency in Chronic Heart Failure: an Observational Study
This completed observational study investigates growth hormone deficiency in patients with chronic heart failure.
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CLINICAL_TRIALS research · 2014-02-20Clinical Trial Update: Heart Failure in the Community
Mayo Clinic conducted a clinical trial on heart failure in the community that has completed; the provided snippet does not include trial res…
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CLINICAL_TRIALS withdrawal · 2014-02-19Clinical Trial Update: A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1) [NA]
The DIOS 1 pilot trial investigating diuretic add-on strategies for chronic heart failure has been withdrawn.