Heart Failure
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CLINICAL_TRIALS trial_result · 2014-06-12Clinical Trial Update: Validation of a Mortality Prediction Model for Acutely Decompensated Heart Failure Patients
A completed clinical trial validating a mortality prediction model for patients with acute decompensated heart failure.
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: TReatment of Atrial Fibrillation With Dual dEfibrillator in Heart Failure Patients [Phase 4]
Phase 4 clinical trial evaluating a dual defibrillator for atrial fibrillation in heart failure patients has completed, with results posted …
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart Failure [Phase 4]
Phase 4 MINERVA trial assessed whether minimizing right ventricular pacing can prevent atrial fibrillation and heart failure. Results were c…
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CLINICAL_TRIALS trial_result · 2014-06-10Clinical Trial Update: Hypertonic Saline Solution in Heart Failure [Phase 2]
Phase 2 trial evaluating hypertonic saline solution in heart failure has completed, with results awaiting final analysis.
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CLINICAL_TRIALS trial_result · 2014-06-10Clinical Trial Update: Blood Pressure Reduction in Heart Failure [Phase 2, Phase 3]
A completed Phase 2/Phase 3 clinical trial evaluated a blood pressure–lowering therapy in patients with heart failure and reported results.
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CLINICAL_TRIALS withdrawal · 2014-06-05Clinical Trial Update: Effects of Nesiritide in Pediatric Patients With Heart Failure [NA]
The pediatric trial evaluating Nesiritide for heart failure (NCT00166010) has been withdrawn.
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CLINICAL_TRIALS research · 2014-06-02Clinical Trial Update: Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure [Phase 1]
Phase 1 clinical trial update from GlaxoSmithKline evaluating MRI measures of lung water with posture changes in healthy volunteers and pati…
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Depression and Self-care in Heart Failure [NA]
A clinical trial examining depression and self-care in heart failure patients has completed.
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Feasibility of Pharmaceutical Interventions in Elderly Heart Failure Patients. [NA]
Clinical trial update indicating the feasibility study in elderly heart failure patients has completed.
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: Vitamin D Supplementation in Chronic Stable Heart Failure [Phase 3]
Phase 3 trial evaluating vitamin D supplementation in adults with chronic stable heart failure and vitamin D deficiency has completed.
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: Implementation of the Hospital to Home (H2H) Heart Failure Initiative [NA]
The Hospital to Home (H2H) heart failure initiative sponsored by the VA Palo Alto Health Care System has completed a clinical trial evaluati…
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CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: Renal Denervation in Chronic Heart Failure [Phase 1]
The document reports the completion of a Phase 1 trial evaluating renal denervation for chronic heart failure.
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CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: Effect of Posture on Left Ventricular (LV) Transvenous Lead Capture Thresholds (EXPECT) [NA]
A terminated clinical trial assessed how body posture affects left ventricular transvenous lead capture thresholds in congestive heart failu…
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CLINICAL_TRIALS research · 2014-05-26Clinical Trial Update: External Sensors for remoTe MoniToring of Heart Failure Patients With Implantable Defibrillators
The document reports on a clinical trial evaluating external sensors for remote monitoring in patients with implantable defibrillators who h…
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Neck-Worn Monitoring Sensor for - A Study for Monitoring Subjects With Fluid-Management Issues During Dialysis
Completed clinical trial evaluating a neck-worn sensor for monitoring fluid management in dialysis patients, sponsored by Baxter Healthcare …
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Supplemental Benefit of Angiotensin Receptor Blocker in Hypertensive Patients With Stable Heart Failure Using Olmesartan [Phase 3]
Phase 3 trial evaluating the supplemental benefit of the angiotensin receptor blocker olmesartan in hypertensive patients with stable heart …
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care [Phase 4]
Phase 4 clinical trial comparing a simplified digoxin dosing nomogram to standard care in heart failure; results posted.
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CLINICAL_TRIALS research · 2014-05-19Clinical Trial Update: Coordinated Assessment of Notifications of Trials Containing Overt Published Errors [NA]
A coordinated assessment is being conducted regarding notifications of clinical trials that contain overt published errors, with Heart Failu…
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CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device [Phase 2]
This document summarizes the completion of a Phase 2 clinical trial evaluating a diagnostic feature in a cardiac resynchronization therapy d…
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CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Care Transitions for Complex Patient - Cycle 1 and Cycle 2 [NA]
Clinical trial update indicating the completion of cycles 1 and 2 of a Duke University study focused on care transitions for complex patient…
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CLINICAL_TRIALS trial_result · 2014-05-14Clinical Trial Update: Improving Care of Patients With Heart Failure [NA]
This clinical trial update reports on a completed study aimed at improving care for patients with heart failure. It examined outcomes relate…
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CLINICAL_TRIALS trial_result · 2014-05-14Clinical Trial Update: South Korean Pitavastatin Heart Failure Study [Phase 4]
A Phase 4 trial evaluating pitavastatin in patients with chronic heart failure has completed.
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CLINICAL_TRIALS research · 2014-05-14Clinical Trial Update: The Cardiac Insufficiency BIsoprolol Study in Japanese Patients With Chronic Heart Failure (CIBIS-J) [NA]
An update on the Cardiac Insufficiency Bisoprolol Study in Japanese patients with chronic heart failure (CIBIS-J). The current trial status …
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: Recombinant Human Relaxin for the Treatment of Decompensated CHF [Phase 2]
A Phase 2 trial of recombinant human relaxin for decompensated congestive heart failure was terminated.
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FDA label_change · 2014-05-06FDA Approved: TOPROL XL — Supplemental Application (Melinta Therapeutics, LLC)
FDA approved a supplemental application for TOPROL XL (metoprolol succinate) filed by Melinta Therapeutics, resulting in labeling changes fo…