Heart Failure
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Renal Artery Denervation in Chronic Heart Failure [Phase 1]
Phase 1 clinical trial update reporting completion of a study evaluating renal artery denervation in patients with congestive heart failure.
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: A Randomized Study of the Efficacy of a New Intervention for Medication Adherence in Chronic Illness: Medications, Meaning and Me (The 3-M Study) [NA]
Duke University completed a randomized trial assessing a new intervention to improve medication adherence in people with heart failure.
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: Early Assessment of Anthracycline-induced Cardiotoxicity (CARDIOTOX)
The CARDIOTOX trial evaluating early assessment of anthracycline-induced cardiotoxicity has been terminated.
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FDA approval · 2016-08-19FDA Approved: BISOPROLOL FUMARATE — Supplemental Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved the supplemental application to market a generic bisoprolol fumarate tablet from Unichem Pharmaceuticals (USA), Inc.
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device (LVAD) [Phase 2]
A Phase 2 trial evaluating dabigatran as an alternative anticoagulant in patients with left ventricular assist devices was terminated.
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Comparison of Long- and Short-acting Diuretics in Congestive Heart Failure [Phase 4]
Phase 4 clinical trial comparing long-acting versus short-acting diuretics in congestive heart failure has completed.
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CLINICAL_TRIALS research · 2016-08-16Clinical Trial Update: Measuring Electrical Resistance of Different Tissues on the Outer Surface of the Heart
The University of Pennsylvania-sponsored trial measured electrical resistance of different tissues on the outer surface of the heart; the st…
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Strain X Cardiopulmonary Test
A clinical trial update for Strain X Cardiopulmonary Test in heart failure; the current status of the trial is unknown.
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Iron Stores and Skeletal Muscle Metabolism in Chronic Heart Failure [Phase 1]
Phase 1 clinical trial investigating iron stores and skeletal muscle metabolism in chronic heart failure has completed.
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: Vitamin D and Mortality in Heart Failure [Phase 4]
A Phase 4 clinical trial evaluated whether vitamin D supplementation affects mortality in patients with congestive heart failure.
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Single Dose Escalation Study in Patients With Chronic Heart Failure [Phase 1]
Bayer sponsors a Phase 1 single-dose escalation trial in patients with chronic heart failure, which has completed.
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Blood Collection of Patient Presenting in the ED and Prescribed a BNP
This clinical trial update notes the completion of NCT02614209, a study sponsored by Fujirebio Diagnostics, Inc., evaluating BNP testing in …
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: Pronostic Value of Endothelial Dysfunction in Heart Failure
A terminated clinical trial investigated whether endothelial dysfunction can prognosticate outcomes in patients with heart failure.
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: The Effects of Inspiratory Muscle Training in Patients With Heart Failure and Obstructive Sleep Apnea Syndrome [NA]
This document provides a status update on a clinical trial evaluating inspiratory muscle training for patients with heart failure, including…
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CLINICAL_TRIALS research · 2016-08-08Clinical Trial Update: Epidemiology of Depression and Heart Failure in Aging
A completed NHLBI-supported observational study examining the epidemiology of depression and heart failure in aging individuals.
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CLINICAL_TRIALS trial_result · 2016-08-05Clinical Trial Update: A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure. [Phase 2]
A Phase 2 trial comparing Aleglitazar with pioglitazone (Actos) in patients with type 2 diabetes and NYHA class II heart failure has complet…
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CLINICAL_TRIALS trial_result · 2016-08-05Clinical Trial Update: Markers of Endothelial Function and Exercise CapaciTy in Patients With Left Ventricular Assist Devices (EFECT LVAD)
This is a completed clinical trial evaluating markers of endothelial function and exercise capacity in patients with left ventricular assist…
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CLINICAL_TRIALS research · 2016-08-03Clinical Trial Update: Effect of Right Bifocal Ventricular Cardiac Pacing on Serum Level Natriuretic Peptides in Patients With Heart Failure [NA]
This entry updates on a clinical trial examining whether right bifocal ventricular pacing affects serum natriuretic peptide levels in patien…
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CLINICAL_TRIALS other · 2016-08-03Clinical Trial Update: Peripherally Inserted Central Catheter Use for Dobutamine Infusion in Heart Failure Patients [NA]
This entry provides an update on a clinical trial evaluating the use of a peripherally inserted central catheter to administer dobutamine to…
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CLINICAL_TRIALS research · 2016-08-02Clinical Trial Update: Cardiovascular Epidemiology in Russian Federation
This is a cardiovascular epidemiology clinical trial update in the Russian Federation. It lists hypertension, coronary artery disease, diabe…
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FDA approval · 2016-07-29FDA Approved: QBRELIS — Original Application (Azurity Pharmaceuticals, Inc.)
The FDA approved QBRELIS (lisinopril) through an original NDA from Azurity Pharmaceuticals. It is indicated for hypertension, heart failure,…
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CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) [Phase 3]
Phase 3 ALLHAT trial update reporting completed results evaluating antihypertensive therapies (chlorthalidone, lisinopril, amlodipine, and d…
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CLINICAL_TRIALS research · 2016-07-29Clinical Trial Update: Examining the Cognitive Benefits of Cardiac Rehabilitation in People With Heart Failure (The CHF CaRe Study)
The CHF CaRe study examines cognitive benefits of cardiac rehabilitation in people with heart failure. Sponsored by the National Heart, Lung…
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CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: Randomized Controlled Trial of Health Care to Elderly Patients. [NA]
A randomized controlled trial evaluating health care for elderly patients sponsored by the Norwegian University of Science and Technology ha…
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CLINICAL_TRIALS withdrawal · 2016-07-29Clinical Trial Update: HEARTS: Heart, Exercise, and Resistance Training Study [NA]
The HEARTS: Heart, Exercise, and Resistance Training Study has been withdrawn.