Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2016-10-04Clinical Trial Update: A Novel Echocardiography Modality to Assess Left Ventricular Dyssynchrony
A clinical trial evaluating a novel echocardiography modality for assessing left ventricular dyssynchrony was withdrawn.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: MultiPoint Pacing IDE Study [Phase 3]
Abbott completed a Phase 3 IDE study evaluating MultiPoint Pacing for heart failure; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Clinical Trials for Elderly Patients With Multiple Disease [NA]
A completed clinical trial update from Restech Srl involving elderly patients with COPD, congestive heart failure, and sleep disordered brea…
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management [Phase 3]
A Phase 3 randomized, double-blind, placebo-controlled trial examined the short-term clinical effects of tolvaptan in patients hospitalized …
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CLINICAL_TRIALS research · 2016-09-27Clinical Trial Update: Left Atrial Volume Index in Asymptomatic Aortic Stenosis
This document provides an update on a clinical trial evaluating left atrial volume index in asymptomatic patients with aortic stenosis.
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FDA approval · 2016-09-22FDA Approved: FUROSEMIDE — Supplemental Application (Hospira, Inc.)
FDA approves Hospira, Inc.'s supplemental application for furosemide, initiating a supplemental approval for the drug. The action updates th…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: Mechanisms and Reversibility of Heart Failure Associated With Diabetes
This completed trial investigates the mechanisms and potential reversibility of heart failure in people with type 2 diabetes.
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: Once-a-day Tacrolimus Conversion Study: The OneTAC Trial [Phase 4]
Phase 4 clinical trial update for the OneTAC Trial evaluating once-daily tacrolimus conversion, sponsored by Newark Beth Israel Medical Cent…
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CLINICAL_TRIALS withdrawal · 2016-09-20Clinical Trial Update: An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine) [Phase 3]
A Phase 3 trial evaluating nesiritide in heart failure patients with reduced kidney function undergoing coronary artery bypass graft surgery…
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FDA approval · 2016-09-19FDA Approved: FUROSEMIDE — Supplemental Application (Phlow Corporation)
FDA approved a supplemental application for furosemide submitted by Phlow Corporation.
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FDA approval · 2016-09-19FDA Approved: SPIRONOLACTONE — Original Application (Accord Healthcare, Inc.)
FDA approves Accord Healthcare, Inc.'s original application for spironolactone (generic), authorizing its use as a potassium-sparing diureti…
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CLINICAL_TRIALS trial_result · 2016-09-16Clinical Trial Update: Clinical Value of Heart Rate Variability Indexes to Predict Outcomes After Exercise Training in Chronic Heart Failure [Phase 4]
Phase 4 trial update evaluating whether heart rate variability indexes can predict outcomes after exercise training in chronic heart failure…
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FDA approval · 2016-09-16FDA Approved: VALSARTAN — Original Application (Macleods Pharmaceuticals Limited)
The FDA approved the original ANDA for valsartan from Macleods Pharmaceuticals Limited, making a generic ARB option available. This approval…
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FDA approval · 2016-09-15FDA Approved: QUINAPRIL — Original Application (Solco Healthcare US, LLC)
FDA approves the original application for Quinapril, granting approval for a generic version manufactured by Solco Healthcare US, LLC.
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FDA approval · 2016-09-13FDA Approved: LISINOPRIL — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for lisinopril submitted by Aurobindo Pharma Limited under ANDA 077622.
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Primary Prevention of Sudden Cardiac Death (PREV-DEATH)
The PREV-DEATH trial, studying primary prevention of sudden cardiac death in chronic heart failure, has completed. The snippet does not prov…
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Effects of CCM-therapy in Patients With Heart Failure
A completed clinical trial evaluating the effects of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure.
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FDA approval · 2016-09-08FDA Approved: LISINOPRIL — Supplemental Application (Solco healthcare U.S., LLC)
The FDA approved a supplemental application for lisinopril from Solco Healthcare U.S., LLC under an ANDA, confirming the approval of this ge…
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CLINICAL_TRIALS withdrawal · 2016-09-07Clinical Trial Update: A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II) [NA]
The DIOS II trial, a prospective pilot study evaluating diuretic add-on strategies in acute decompensated heart failure, has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-09-05Clinical Trial Update: Haemodynamic Effects of Dobutamine and Nitrite in LV Dysfunction
This clinical trial update reports on the haemodynamic effects of dobutamine and nitrite in left ventricular dysfunction (heart failure); no…
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CLINICAL_TRIALS trial_result · 2016-09-01Clinical Trial Update: Liraglutide and Heart Failure in Type 2 Diabetes [Phase 2]
This is a Phase 2 trial update for liraglutide in people with type 2 diabetes and heart failure. The study status is completed, but the snip…
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Safety Study of Chimeric Natriuretic Peptide(CD-NP) in Stable LVAD Patients [Phase 1]
A Phase 1 safety study of Chimeric Natriuretic Peptide (CD-NP) in stable LVAD patients has completed.
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Correlating Noninvasive Cardiovascular Measures to Left Ventricular End Diastolic Pressure in Heart Failure
This clinical trial update notes the termination of a study evaluating noninvasive cardiovascular measures for estimating left ventricular e…
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: Sensor Optimization of Cardiac Resynchronization Therapy Response [NA]
A completed Medtronic-sponsored trial evaluated sensor-based optimization of Cardiac Resynchronization Therapy response in heart failure; re…
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CLINICAL_TRIALS research · 2016-08-26Clinical Trial Update: Epidemiology and Prognostic of the Acute Heart Failure
This clinical trial update investigates the epidemiology and prognosis of acute heart failure, including decompensated chronic heart failure…