Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: AI-based Echocardiographic Quantification in Heart Failure
A clinical trial update describes an AI-based echocardiographic quantification approach being studied for heart failure with preserved eject…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation
This ClinicalTrials.gov listing describes a study evaluating left ventricular reverse remodeling after surgical correction of aortic regurgi…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Serum IGF1 on Female HFpEF Patients
This clinical trial update examines the role of serum IGF1 in female patients with heart failure with preserved ejection fraction, with enro…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Comparison of the Effect of Two Types of Physical Exercises in Patients With Heart Failure With Preserved Ejection Fraction [NA]
A completed clinical trial comparing two types of physical exercise in patients with heart failure with preserved ejection fraction to evalu…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: LCZ696 in Advanced LV Hypertrophy and HFpEF [Phase 2]
A Phase 2 trial of LCZ696 (sacubitril/valsartan) in advanced left ventricular hypertrophy and heart failure with preserved ejection fraction…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Matching Perfusion and Metabolic Activity in HFpEF [Phase 2]
Phase 2 clinical trial update on matching perfusion and metabolic activity in heart failure with preserved ejection fraction (HFpEF); the st…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF) [Phase 3]
Phase 3 trial PREFER-HF evaluating intravenous iron therapy in patients with heart failure with preserved ejection fraction and iron deficie…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Effects of Sauna on Cardiac and Skeletal Muscle Function in Patients With HFpEF (SAUNA-HFpEF) [NA]
This completed trial SAUNA-HFpEF studied the effects of sauna exposure on cardiac and skeletal muscle function in patients with heart failur…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Managing Congestion in Heart Failure: A Mechanistic Study in Patients With HFpEF [NA]
A clinical trial update describing a mechanistic study to manage congestion in patients with heart failure with preserved ejection fraction …
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CLINICAL_TRIALS withdrawal · 2025-05-15Clinical Trial Update: Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction [Phase 2]
A Phase 2 trial evaluating the selective PDE9 inhibitor IMR-687 for heart failure with preserved ejection fraction has been withdrawn.
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Heart Failure and Preserved Ejection Fraction: Observation of Its Progression and Prognosis (HOPP-BERN)
This listing provides an update on a clinical trial studying progression and prognosis in heart failure with preserved ejection fraction (HF…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: UK Heart Failure With Preserved Ejection Fraction
A UK clinical trial update indicates recruitment is ongoing for a study on heart failure with preserved ejection fraction (HFpEF) sponsored …
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Efficacy and Safety of Xinyue Capsule in the Treatment of Heart Failure With Preserved Ejection Fraction [Phase 3]
A Phase 3 trial is evaluating the efficacy and safety of Xinyue Capsule for heart failure with preserved ejection fraction; the study is cur…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Pilot Study Lp299v Supplementation in Chronic Heart Failure [NA]
A pilot study is evaluating the probiotic Lp299v as a supplement in chronic heart failure and is currently recruiting. The trial includes pa…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF [NA]
UT Southwestern Medical Center is conducting a recruiting study to test breathing-targeted interventions aimed at improving functional outco…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Staging Heart Failure With Preserved Ejection Fraction
This clinical trial update describes staging approaches for heart failure with preserved ejection fraction (HFpEF); the study is currently n…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Mechanisms of LV Remodeling in Hypertensive Patients Working on a Rotational Expeditionary Basis in the Arctic
This clinical trial update outlines a study sponsored by Tomsk National Research Medical Center of the Russian Academy of Sciences examining…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Heart Failure With Preserved Ejection Fraction and Its Cardiac MR Characteristics of Different Subtypes
This document updates a clinical trial investigating heart failure with preserved ejection fraction (HFpEF) and its cardiac MRI characterist…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) [Phase 1]
A Phase 1 clinical trial update for an investigational therapy from Secretome Therapeutics in heart failure with preserved ejection fraction…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Exercise Lower-body Negative Pressure in Heart Failure With Preserved Ejection Fraction [NA]
A clinical trial is evaluating exercise using lower-body negative pressure for patients with heart failure with preserved ejection fraction,…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Ketogenic Diet vs Mixed Diet in Patients With Heart Failure [NA]
This clinical trial compares a ketogenic diet to a mixed diet in patients with heart failure with preserved ejection fraction and is current…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Evaluation of GeranylGeranylAcetone in Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 clinical trial evaluating GeranylGeranylAcetone for heart failure with preserved ejection fraction has completed. Sponsor/locations …
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Abnormal Vascular, Metabolic, and Neural Function During Exercise in Heart Failure With Preserved Ejection Fraction [NA]
A clinical trial exploring abnormal vascular, metabolic, and neural function during exercise in heart failure with preserved ejection fracti…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention Trial [NA]
A recruiting clinical trial evaluating bariatric surgery to assess treatment efficacy in patients with heart failure with preserved ejection…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Spironolactone in the Treatment of Heart Failure [Phase 3]
A Phase 3 trial evaluating spironolactone for heart failure with mid-range or preserved ejection fraction has been terminated.