Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
A University of Edinburgh-led clinical trial update describing a recruiting study that uses cardiac imaging to evaluate myocardial fibrosis …
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Dapagliflozin With or Without Spironolactone for HFpEF [Phase 2, Phase 3]
Phase 2/3 trial update evaluating dapagliflozin with or without spironolactone for heart failure with preserved ejection fraction has comple…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Study of HS235 in Obese Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF) [Phase 1]
A Phase 1 clinical trial evaluating HS235 in obese patients with pulmonary hypertension and heart failure with preserved ejection fraction (…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter Study [NA]
A prospective randomized, sham-controlled global trial sponsored by Occlutech International AB is evaluating flow regulation by opening the …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Platelet Derived Growth Factor Receptor ß (PDGFRß) Imaging in Cardiac Fibrosis
Clinical trial update investigating PDGFRβ imaging to assess cardiac fibrosis. The study includes patients with ST-Elevation Myocardial Infa…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Hemodynamic-GUIDEd Management of Heart Failure [NA]
Abbott Medical Devices completed a trial on hemodynamic-guided management of heart failure; results were posted on 2025-08-07.
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Provocative Tests for HFpEF
A clinical trial update indicates an ongoing study investigating provocative tests for heart failure with preserved ejection fraction, spons…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Neuromuscular Fatigue and Exercise Capacity in Patients With Type 2 Diabetes Mellitus and HFpEF
This item reports a completed clinical trial evaluating neuromuscular fatigue and exercise capacity in patients with Type 2 diabetes mellitu…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF) [NA]
Clinical trial update announcing ongoing recruitment for a study evaluating a dietary fiber supplement in people with Type 2 diabetes mellit…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Screening and Phenotyping of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction . [NA]
This clinical trial update notes a planned study to screen and phenotype pulmonary hypertension in patients with heart failure with preserve…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF) [NA]
This update concerns the early feasibility study of the PeriCut Catheter System for heart failure with preserved ejection fraction, which is…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: WISE CVD - Continuation (WISE HFpEF)
A continuation of the WISE CVD trial targeting HFpEF and microvascular coronary dysfunction is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: The Safety and Efficacy of Pulsed Field Ablation for Patients With Persistent Atrial Fibrillation Comorbid With HFpEF. [NA]
This clinical trial update indicates that the study evaluating pulsed field ablation for persistent atrial fibrillation in patients with hea…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients [Phase 4]
Phase 4 clinical trial of sotagliflozin in heart failure with preserved ejection fraction has completed.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Frailty and Outcomes in Older Heart Failure Patients With Ejection Fraction >40%
An update on an ongoing clinical trial evaluating frailty and outcomes in older heart failure patients with EF >40%, covering heart failure …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With Obesity [Phase 2]
A Phase 2 clinical trial evaluating IBI362 in patients with obesity and heart failure with preserved ejection fraction (HFpEF) or mildly red…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Weight Loss as Therapy for Heart Failure With Preserved Ejection Fraction [NA]
A completed clinical trial evaluating weight loss as a therapeutic approach for heart failure with preserved ejection fraction (HFpEF).
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches [Phase 4]
This Phase 4 trial update outlines IRONICA, a study comparing oral and IV iron repletion in patients with heart failure and iron deficiency/…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity
This clinical trial update describes an ongoing study examining the epidemiology and pathophysiology of kidney disease in patients with hear…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure [NA]
This document provides an update on a clinical trial evaluating novel respiratory training as part of palliative care for older adults with …
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Physical Rehabilitation for Older Patients With Acute Heart Failure With Preserved Ejection Fraction [NA]
A Wake Forest University Health Sciences-sponsored clinical trial is evaluating physical rehabilitation for older patients with acute heart …
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
The WISE Pre-HFpEF trial at Cedars-Sinai is currently recruiting to study coronary microvascular dysfunction in patients with heart failure …
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: IMPROVE-DiCE: Study to Evaluate Effect of IMB-1018972 on Cardiac Energetics in T2DM & Obesity (Pt 1) With HFpEF (Pt 2) [Phase 2]
This update reports the completion of a Phase 2 study evaluating IMB-1018972 for improving cardiac energetics in adults with type 2 diabetes…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Exercise Intervention in Patients With Heart Failure With Preserved and Reduced Ejection Fraction [NA]
This clinical trial update notes an exercise intervention is being studied in patients with heart failure with preserved ejection fraction a…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Effect of Nurse-assessed Remote Ischemic Preconditioning on Improving Exercise Capacity, Endothelial Function, and Arterial Stiffness in Patients With Heart Failure With Preserved Ejection Fraction [NA]
This clinical trial update outlines a study evaluating nurse-assisted remote ischemic preconditioning to improve exercise capacity and vascu…