Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction
A University of Leicester-sponsored clinical trial is investigating the role of epicardial adiposity in heart failure with preserved ejectio…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT [Phase 2]
Phase 2 study evaluating mavacamten in participants with heart failure with preserved ejection fraction and elevated NT-proBNP (with or with…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: HEART Camp Connect: A Feasibility Study [NA]
The HEART Camp Connect feasibility trial in heart failure with preserved ejection fraction was terminated, and results were posted on 2025-0…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Longitudinal Multimarker Risk Models for Very Elderly Patients With Heart Failure and Preserved Ejection Fraction
This clinical trial update describes a longitudinal study using multimarker risk models in very elderly patients with heart failure with pre…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function
A completed study evaluates how cardiac diastolic function and coronary microvascular function relate to prognosis in ischemic heart disease…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study [NA]
A pilot study is ongoing to assess the feasibility and effectiveness of eccentric exercise in sarcopenic older adults with heart failure (bo…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool? [NA]
A clinical trial registry entry describes evaluating noninvasive elastography to assess myocardial stiffness as a diagnostic tool for isolat…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Metformin for Pulmonary Hypertension HFpEF [Phase 2]
A Phase 2 clinical trial sponsored by the University of California, San Francisco is evaluating metformin for pulmonary hypertension in pati…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: "HerzCheck" - Detection of Early Heart Failure Using Telemedicine in Structurally Weak Regions [NA]
The HerzCheck study is a telemedicine-based approach for early detection of heart failure with preserved ejection fraction; it is currently …
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Copenhagen Heart Failure With Preserved Ejection Fraction
An ongoing clinical trial update for a Copenhagen study evaluating heart failure with preserved ejection fraction; the study is currently re…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences
A University of Leeds-led clinical trial is recruiting to study the cellular crosstalk and consequences of diabetes type 2 in patients with …
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Effects of a Supervised Training Program on Functional Capacity in Patients With HFpEF and Chronotropic Incompetence [NA]
This clinical trial update reports the completion of a supervised training program study assessing its effects on functional capacity in pat…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Role of Colchicine as Anti-Inflammatory Therapy in HFpEF [Phase 3]
A Phase 3 clinical trial from Cairo University is evaluating whether colchicine can act as an anti-inflammatory therapy in heart failure wit…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
This entry describes an ongoing clinical trial evaluating AI-enabled, direct-from-ECG assessment of ejection fraction severity using the COR…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Association of Heterogeneous Circulating Biomarkers and Anamnestic Factors of Pregnancy Adverse Course and Outcomes With the Prognosis of Heart Failure With Preserved Ejection Fraction
A clinical trial exploring how heterogeneous circulating biomarkers and pregnancy-related factors influence prognosis in heart failure with …
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Transcutaneous Vagus Nerve Stimulation in Heart Failure [NA]
Completed clinical trial evaluating transcutaneous vagus nerve stimulation for heart failure, including preserved and mid-range ejection fra…
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CLINICAL_TRIALS research · 2025-01-21Clinical Trial Update: Multiple-biomarker Approach for Individualized Treatment of Heart Failure with Preserved Ejection Fraction
This ClinicalTrials.gov entry describes an ongoing study using a multi-biomarker approach to tailor treatment for heart failure with preserv…
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: Efficacy and Safety of Qishenyiqi Dripping Pills for Treating Chronic Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 trial evaluating the efficacy and safety of Qishenyiqi Dripping Pills for chronic heart failure with preserved ejection fraction has…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Myeloperoxidase (MPO) Inhibitor A_Zeneca for Heart Failure With Preserved Ejection Fraction (HFpEF) [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the myeloperoxidase inhibitor A_Zeneca in heart failure with preserved ejection fraction has completed, with re…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Developing Oral LT3 Therapy for Heart Failure - HFpEF [Phase 1, Phase 2]
Phase 1/2 trial evaluating oral liothyronine (LT3) for heart failure with preserved ejection fraction and low T3 syndrome has completed, wit…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction [NA]
This clinical trial update reports on research into the mechanisms behind exercise intolerance in heart failure with preserved ejection frac…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Effectiveness of CRD-740 in Heart Failure [Phase 2]
Cardurion Pharmaceuticals reports the Phase 2 trial of CRD-740 in heart failure has been terminated, with results posted.
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Study on Heart Failure with Preserved Ejection Fraction with Qishen Granules [NA]
A clinical trial is evaluating Qishen Granules for heart failure with preserved ejection fraction and it is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: HFPEF-project: Heart Failure Phenotyping - Exploring the Fingerprints
This update describes an ongoing University of Helsinki study called HFPEF-project: Heart Failure Phenotyping - Exploring the Fingerprints, …
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Atrial Fibrillation with Heart Failure with Preserved Ejection Fraction: Treatment Strategies-Catheter Ablation Vs. Anti-Atrial Arrhythmia Drugs [NA]
This ClinicalTrials.gov entry describes a study comparing catheter ablation versus anti-arrhythmic drugs for atrial fibrillation in patients…