Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Transitions of Care Clinic (TOCC) [NA]
Clinical trial update for the Transitions of Care Clinic (TOCC) indicates the study is currently recruiting. It targets heart failure with p…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinical Course and Prognosis
A recruiting clinical trial studying the clinical course and prognosis of heart failure with preserved ejection fraction in patients with ch…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Role of Cardiopulmonary Exercise Testing in People With Heart Failure With Preserved Ejection Fraction
A completed clinical trial evaluating the role of cardiopulmonary exercise testing in people with heart failure with preserved ejection frac…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF) [Phase 2]
A Phase 2 study evaluating LY3540378 in participants with worsening heart failure with preserved ejection fraction was terminated, and the r…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Electroporation Treatment for Early AF Management in Heart Failure With Preserved Ejection Fraction (HFpEF) Pilot Study [NA]
A pilot clinical trial update evaluating electroporation treatment for early atrial fibrillation management in patients with heart failure w…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Emulation of the STEP-HFpEF DM Heart Failure Trial in Healthcare Claims Data
A study update describing emulation of the STEP-HFpEF trial in healthcare claims data for patients with type 2 diabetes mellitus and heart f…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data
Brigham and Women’s Hospital reports a completed study that emulates the SUMMIT heart failure trial using healthcare claims data. The resear…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF [Phase 4]
Phase 4 clinical trial evaluating blockade of calcium channels and beta-adrenergic receptors for hypertension in patients with heart failure…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction
A completed comparative effectiveness trial evaluated tirzepatide versus semaglutide in adults with type 2 diabetes and heart failure with p…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: External Body Pressure in Heart Failure With Preserved Ejection Fraction [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating external body pressure in heart failure with preserved ejection fraction has completed.
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CLINICAL_TRIALS other · 2026-01-28Clinical Trial Update: Cardiac MRI-Derived Pressure-Volume Loop Analysis in Heart Failure With Preserved Ejection Fraction
This clinical trial update notes ongoing enrollment for a study evaluating cardiac MRI-derived pressure-volume loop analysis in heart failur…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Predicting Heart Failure Outcomes With Biomarkers and Imaging
A completed clinical trial evaluating whether circulating biomarkers and imaging findings can predict outcomes across different forms of hea…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction [NA]
Medtronic is conducting a study on fast induced remodeling in heart failure with preserved ejection fraction and concentric hypertrophy. The…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction
This is an update on a hospital registry trial examining decompensated heart failure with preserved ejection fraction, including patients wi…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Allopurinol Improves Heart Function in African Americans With Resistant Hypertension [Phase 2]
Phase 2 clinical trial evaluating allopurinol to improve heart function in African Americans with resistant hypertension and heart failure w…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study
A prospective, single-center cohort study aiming to subtype heart failure patients using multi-omics data and clinical indicators to refine …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial of JK07 for heart failure (reduced and preserved ejection fraction) with Group 2 pulmonary hypertension is currently …
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction [NA]
A clinical trial update for HEART Camp Connect evaluating a structured exercise program for adults with heart failure with preserved ejectio…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Assessment of CCM in HF With Higher Ejection Fraction [NA]
Clinical trial update on Cardiac Contractility Modulation (CCM) for heart failure across multiple ejection fraction subtypes; the study is c…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF [Phase 2]
This clinical trial update describes a Phase 2 study evaluating CK-4021586 in heart failure with preserved ejection fraction to assess safet…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Pulmonary Artery Denervation for Heart Failure With Preserved Left Ventricular Ejection Fraction [NA]
Clinical trial evaluating pulmonary artery denervation for heart failure with preserved ejection fraction (HFpEF); the study is not yet recr…
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CLINICAL_TRIALS withdrawal · 2026-01-09Clinical Trial Update: Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac Hypertrophy [Phase 2]
Phase 2 trial evaluating the reverse remodeling effects of the investigational drug CDR132L in patients with heart failure with preserved ej…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients. [Phase 2]
A Phase 2 trial evaluated mangafodipir as an intracellular MRI contrast agent by measuring manganese uptake in patients with heart failure w…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Accelerated Pacing and Cardiac Filling Pressures During Exercise in Patients With Heart Failure With Preserved Ejection Fraction [NA]
This clinical trial update describes an ongoing study investigating accelerated pacing and its effects on cardiac filling pressures during e…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Descriptive Study of Circulating Gene or Protein Inflammatory Biomarkers and Bioimpedance Parameters in a Population of Patients Hospitalized for Decompensated Heart Failure With Preserved or Mildly Reduced Cardiac Function
Describes a descriptive clinical trial evaluating circulating inflammatory biomarkers and bioimpedance parameters in patients hospitalized f…