Head and Neck Squamous Cell Carcinoma
📧 Sign up to get email alerts when something new happens for Head and Neck Squamous Cell Carcinoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: INRT-AIR: A Prospective Phase II Study of Involved Nodal Radiation Therapy [Phase 2]
A Phase II study evaluating involved nodal radiation therapy (INRT-AIR) for head and neck squamous cell carcinoma has completed and posted r…
-
CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update for PF-07265028 as a single agent and in combination with sasanlimab in advanced/metastatic solid tumors has b…
-
CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Postoperative aRCH With Cisplatin Versus aRCH With Cisplatin and Pembrolizumab in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial comparing postoperative adjuvant radiochemotherapy with cisplatin alone versus cisplatin plus pembrolizumab in locally advan…
-
CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of intravenous QEQ278 in patients with advanced solid tumors has been terminated.
-
CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer [Phase 2]
Phase 2 study evaluating tadalafil in combination with pembrolizumab in recurrent or metastatic head and neck cancer has completed enrollmen…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Reduction in the Number of Chemotherapy Cycles in Combination With Pembrolizumab in First-line Treatment of PD-L1-positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinomas [Phase 2]
Phase 2 trial investigating reducing the number of chemotherapy cycles in combination with pembrolizumab as first-line treatment for PD-L1–p…
-
CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors [Phase 2]
A Phase 2 study evaluating vobramitamab duocarmazine in metastatic castration-resistant prostate cancer and other solid tumors was terminate…
-
CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Effect of Prolonged Nightly Fasting on Immunotherapy Outcomes in HNSCC - Role of Gut Microbiome [NA]
A completed clinical trial evaluating whether prolonged nightly fasting influences immunotherapy outcomes in head and neck cancer and the ro…
-
CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Trial of the Combination of GX-188E Vaccination, GX-I7 and Pembrolizumab in Patients With Advanced, Resectable HPV Type 16 and/or 18 Positive Head and Neck Cancer [Phase 2]
A Phase 2 trial is evaluating a combination of GX-188E vaccination, GX-I7, and pembrolizumab in patients with advanced, resectable HPV16/18-…
-
CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating a binary oncolytic adenovirus in combination with a HER2-specific autologous CAR-VST for advanced HER2-pos…
-
CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck [Phase 2]
This Phase 2 trial update assesses dual EGFR inhibition with afatinib and cetuximab in advanced head and neck squamous cell carcinoma, with …
-
CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma [NA]
A completed clinical trial evaluating hypofractionated radiotherapy in elderly patients with head and neck squamous cell carcinoma (NCT04284…
-
CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: A Phase II Clinical Trial of Anti-EGFR Antibody-drug Conjugate (ADC) Combined With or Without Immune Checkpoint Inhibitors in the Neoadjuvant Treatment of Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II trial evaluating an anti-EGFR antibody-drug conjugate as neoadjuvant therapy for resectable locally advanced head and neck squamous…
-
CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC [Phase 2]
A Phase 2 trial evaluating danvatirsen in combination with pembrolizumab for head and neck squamous cell carcinoma has been terminated, with…
-
CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating metformin hydrochloride in combination with doxycycline for head and neck squamous cell carcinoma has be…
-
CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade [Phase 1, Phase 2]
Phase 1/2 trial evaluating interleukin-2 with radiotherapy and pembrolizumab in patients refractory to checkpoint blockade; results have bee…
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with cetuximab for recurrent/metastatic head and neck squamous cell carcinoma; the stu…
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: A Window of Opportunity Study to Assess the Modulation of Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) By Preoperative Treatment With BYL719 [NA]
A completed window-of-opportunity trial in head and neck squamous cell carcinoma evaluated biomarker modulation after preoperative BYL719 (a…
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Multispectral Optoacoustic Tomography in Head and Neck Squamous Cell Cancer [NA]
A clinical trial evaluating multispectral optoacoustic tomography in head and neck squamous cell carcinoma has been suspended.
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Pembrolizumab Plus Olaparib in LA-HNSCC [Phase 2]
A phase 2 trial evaluating pembrolizumab in combination with olaparib for locally advanced head and neck squamous cell carcinoma is currentl…
-
CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: First in Human Study of SIM0610 in Solid Tumors [Phase 1]
A first-in-human Phase 1 study of SIM0610 in solid tumors is underway, evaluating safety and dosing across multiple indications including No…
-
CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications [Phase 1]
A Phase 1 clinical trial update describes evaluation of BBI-355 (CHK1 inhibitor) in combination with BBI-825 (RNR inhibitor) for tumors with…
-
CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: NBTXR3, Radiation Therapy, and Pembrolizumab for the Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Cancer [Phase 2]
A Phase 2 trial evaluating NBTXR3 with radiation therapy and pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma…
-
CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1]
A Phase 1 clinical trial conducted by Cue Biopharma in patients with HPV16-positive recurrent or metastatic head and neck squamous cell carc…
-
CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Predictive Value of Diffusion-weighted MRI Performed in Early Post-treatment in the Occurrence of Tumor Recurrence or Progression in Head and Neck Squamous Cell Carcinoma Treated With Chemoradiotherapy: a Pilot Study [NA]
This completed pilot study evaluated diffusion-weighted MRI performed early after chemoradiotherapy to predict recurrence or progression in …