Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-06-30Clinical Trial Update: GVH 022P: Study Using Anti Tumor Necrosis Factor Antibody (Infliximab) for Treatment of Acute Graft Versus Host Disease [Phase 1]
Phase 1 study evaluating infliximab for acute graft-versus-host disease has been completed. The trial explored the anti-TNF antibody as a tr…
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CLINICAL_TRIALS withdrawal · 2009-06-18Clinical Trial Update: Prevention of the Graft-Versus-Host-Disease in Patients After Stem Cell Transplantation With Tacrolimus and Everolimus [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating tacrolimus and everolimus to prevent graft-versus-host disease after stem cell transplantation w…
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CLINICAL_TRIALS research · 2009-06-03Clinical Trial Update: Ocular Graft Versus Host Disease After Hematopoietic Stem Cell Transplantation in Adults
An update on a clinical trial studying ocular graft-versus-host disease after hematopoietic stem cell transplantation in adults; the current…
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CLINICAL_TRIALS trial_result · 2009-06-02Clinical Trial Update: A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant Recipients [Phase 4]
Phase 4 study evaluating withdrawal strategies for steroids or tacrolimus in kidney transplant recipients; completed with results posted in …
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CLINICAL_TRIALS trial_result · 2009-05-12Clinical Trial Update: Analysis of the Clinical and Histological Correlation of Oral Graft-Versus-Host-Disease (GVHD)
Completed clinical trial analysis examining the clinical and histological correlation of oral graft-versus-host disease.
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CLINICAL_TRIALS withdrawal · 2009-04-29Clinical Trial Update: Anti-CD3 & Anti-CD7 Ricin A Immunotoxin-Combination for Acute Graft Versus Host Disease [Phase 1, Phase 2]
A Phase 1/2 trial evaluating an anti-CD3 and anti-CD7 ricin A immunotoxin for acute graft-versus-host disease has been withdrawn.
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CLINICAL_TRIALS research · 2009-03-05Clinical Trial Update: Safety Study of Calcineurin Inhibitor Free GvHD Prophylaxis in Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
Clinical trial update describing a safety study of calcineurin inhibitor-free graft-versus-host disease prophylaxis in patients undergoing a…
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CLINICAL_TRIALS trial_result · 2009-02-03Clinical Trial Update: Pentostatin for High Risk and Refractory Chronic Graft Versus Host Disease in Children [Phase 2]
This update reports on the completion of a Phase 2 study of pentostatin for high-risk and refractory chronic graft-versus-host disease in pe…
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CLINICAL_TRIALS trial_result · 2008-12-23Clinical Trial Update: Study of MEDI 507 in the Treatment of Pediatric Patients [Phase 1]
This update reports the completion of a Phase 1 trial of MEDI-507 in pediatric patients with graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2008-12-15Clinical Trial Update: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant
A completed clinical trial from Vanderbilt University evaluating immunoregulatory cells to prevent or mitigate graft-versus-host disease in …
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CLINICAL_TRIALS trial_result · 2008-12-15Clinical Trial Update: Repository: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant
Clinical trial evaluating immunoregulatory cells in hematopoietic stem cell transplantation has completed.
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CLINICAL_TRIALS trial_result · 2008-12-11Clinical Trial Update: Trial for Evaluation of Safety of Escalating Dose Levels of MEDI-507 in Patients for Treatment of at Least Grade II Graft-Versus-Host Disease (GvHD) [Phase 1]
A Phase 1 study evaluating escalating dose safety of MEDI-507 in patients with graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2008-12-11Clinical Trial Update: Study of MEDI-507 in With Steroid-Resistant Acute Graft-Versus-Host Disease [Phase 1]
Phase 1 study of MEDI-507 for steroid-resistant acute graft-versus-host disease in cancer patients has completed.
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EMA withdrawal · 2008-05-23EMA Application withdrawn: orBec (beclomethasone dipropionate) — DOR BIOPHARMA UK Ltd
The EMA withdrew the application for orBec (beclomethasone dipropionate) for graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2008-03-14Clinical Trial Update: Study Evaluating Sirolimus in Kidney Transplant Recipients. [Phase 3]
Phase 3 clinical trial evaluating sirolimus in kidney transplant recipients has been completed, with Wyeth (now Pfizer) as sponsor.
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CLINICAL_TRIALS research · 2008-03-04Clinical Trial Update: Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek Cells
The update discusses whether transplanted stem cells can mature into salivary gland and cheek cells, in a study sponsored by the National In…
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Study Evaluating Sirolimus in Kidney Transplant Recipients in India [Phase 4]
This update reports the completion of a Phase 4 trial evaluating sirolimus in kidney transplant recipients in India.
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CLINICAL_TRIALS trial_result · 2007-11-06Clinical Trial Update: Trial of Filgrastim Versus Placebo Following Allogeneic Bone Marrow Transplantation [Phase 3]
Phase 3 trial comparing filgrastim to placebo after allogeneic bone marrow transplantation; graft-versus-host disease is the listed conditio…
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CLINICAL_TRIALS trial_result · 2007-09-24Clinical Trial Update: Active Immunization of Sibling Bone Marrow Transplant Donors Against Purified Myeloma Protein of the Recipient Undergoing Allogeneic Bone Marrow Transplantation [Phase 3]
Phase 3 trial evaluating immunization of sibling bone marrow donors against the recipient's purified myeloma protein undergoing allogeneic b…
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CLINICAL_TRIALS trial_result · 2007-07-06Clinical Trial Update: Evaluation of the Role of Mesenchymal Stem Cells in the Treatment of Graft Versus Host Disease [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating mesenchymal stem cells for the treatment of graft-versus-host diseas…
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CLINICAL_TRIALS research · 2007-03-22Clinical Trial Update: Treatment of Refractory (Acute or Chronic) Graft-Versus-Host Disease by the Infusion of Expanded in-Vitro Allogenic Mesenchymal Stem Cell [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating infusion of expanded allogeneic mesenchymal stem cells to treat refractory gra…
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CLINICAL_TRIALS research · 2007-03-22Clinical Trial Update: Dendritic Cells in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation
This clinical trial update discusses dendritic cell therapy in patients after allogeneic hematopoietic stem cell transplantation, with a foc…
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CLINICAL_TRIALS trial_result · 2006-11-07Clinical Trial Update: Intra-Arterial Catheter Directed Therapy for Severe Graft vs. Host Disease (GVHD) [Phase 1, Phase 2]
This entry notes the completion of a Phase 1/2 clinical trial evaluating intra-arterial catheter-directed therapy for severe graft-versus-ho…
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CLINICAL_TRIALS trial_result · 2006-09-20Clinical Trial Update: A Study to Assess the Safety and Efficacy of a Tacrolimus New Oral Formulation (MR4) in BMT Patients-Extension- [Phase 2]
ClinicalTrials.gov entry notes completion of a Phase 2 extension study evaluating the safety and efficacy of a new oral tacrolimus formulati…
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CLINICAL_TRIALS trial_result · 2006-09-20Clinical Trial Update: A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipients [Phase 2]
Completion of a Phase 2 study evaluating the efficacy, safety, and pharmacokinetics of a new oral tacrolimus formulation (MR4) in bone marro…