Graft-versus-host Disease
📧 Sign up to get email alerts when something new happens for Graft-versus-host Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease [Phase 1, Phase 2]
Phase 1/2 trial evaluating topical fibrinogen-depleted human platelet lysate for dry eye caused by graft-versus-host disease has completed.
-
CLINICAL_TRIALS trial_result · 2021-07-22Clinical Trial Update: Study of IL-22 IgG2-Fc (F-652) for Subjects With Grade II-IV Lower GI aGVHD [Phase 1, Phase 2]
Phase 1/2 study evaluating IL-22 IgG2-Fc (F-652) for acute graft-versus-host disease (aGVHD) shows results posted after completion.
-
CLINICAL_TRIALS trial_result · 2021-06-30Clinical Trial Update: Outcomes of Patients After Allo-HSCT With Decitabine and NAC [Phase 3]
Phase 3 trial update on outcomes after allogeneic hematopoietic stem cell transplantation using decitabine and NAC for engraftment failure a…
-
CLINICAL_TRIALS trial_result · 2021-06-23Clinical Trial Update: Discontinuation or Continuation of Immunosuppressive Therapy in Participants With Chronic Graft Versus Host Disease [Phase 2]
Phase 2 trial update on discontinuation or continuation of immunosuppressive therapy in participants with chronic graft-versus-host disease …
-
CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: Phase II Trial of Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft-Versus-Host Disease (GVHD) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-002) [Phase 2]
Phase II trial update on Efprezimod Alfa (CD24Fc, MK-7110) for prevention of acute GVHD after myeloablative allogeneic HSCT; trial completed…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Vismodegib in Treating Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease [Phase 2]
Phase 2 trial update for vismodegib in steroid-refractory chronic graft-versus-host disease has been terminated with posted results.
-
CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: A Proof of Concept Pilot Trial of Alpha-1-Antitrypsin for Pre-Emption Of Steroid-Refractory Acute GVHD [Phase 2]
Phase 2 pilot trial evaluating alpha-1-antitrypsin for pre-emption of steroid-refractory acute GVHD has been completed, with results posted.
-
CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT [Phase 2]
Phase 2 trial evaluating PT-CY with or without low-dose ATG for lymphoid malignancies undergoing allogeneic hematopoietic stem cell transpla…
-
CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation [Phase 3]
Phase 3 trial update on prevention of graft-versus-host disease in patients with advanced leukemia or lymphoma undergoing peripheral stem ce…
-
CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD) [Phase 3]
Phase 3 trial evaluating ibrtutinib in combination with corticosteroids versus placebo with corticosteroids for new onset chronic graft-vers…
-
CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Single-centre Study of Everolimus as GvHD Prophylaxis After Post-Transplantation Cyclophosphamide After Allogeneic SCT [Phase 2]
Phase 2 single-centre trial evaluating everolimus as prophylaxis for graft-versus-host disease after post-transplant cyclophosphamide in all…
-
CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Bridging Pediatric and Adult Biomarkers in Graft-Versus-Host Disease
A completed clinical trial investigating bridging pediatric and adult biomarkers in graft-versus-host disease with results posted in 2021.
-
CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Treatment of Steroid Refractory Gastro-intestinal Acute GVHD afteR AllogeneiC HSCT With fEcal Microbiota tranSfer [Phase 2]
Phase 2 clinical trial evaluating fecal microbiota transplantation for treatment of steroid-refractory gastrointestinal acute graft-versus-h…
-
CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: Exploratory Safety Study of ALD518 in Subjects With Steroid-refractory Acute Graft Versus Host Disease (GVHD) [Phase 1, Phase 2]
Exploratory safety study of ALD518 in steroid-refractory acute graft-versus-host disease (GVHD) across Phase 1/2, terminated with posted res…
-
CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer [Phase 2]
Phase 2 clinical trial evaluating beclomethasone dipropionate to prevent acute graft-versus-host disease in patients undergoing donor stem c…
-
CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Sitagliptin for the Treatment of Grade 3-4 and Refractory Acute Graft-versus-host Disease [Phase 2]
A Phase 2 clinical trial evaluating sitagliptin for grade 3-4 and refractory acute graft-versus-host disease.
-
CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Studying Changes in Physical Function Measures in Stem Cell Transplant Patients at Risk for Steroid Myopathy [NA]
Clinical trial update on changes in physical function measures in stem cell transplant patients at risk for steroid myopathy; study terminat…
-
CLINICAL_TRIALS trial_result · 2020-12-31Clinical Trial Update: MSC for Treatment of cGVHD After Allo-HSCT [Phase 2]
Phase 2 clinical trial update for mesenchymal stem cells aimed at treating chronic graft-versus-host disease after allogeneic hematopoietic …
-
CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating sitagliptin for prevention of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantat…
-
CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Pharmacokinetics of Micafungin Given Twice Weekly Intravenously Compared to Micafungin Given Daily to Patients at Risk for Developing an Invasive Fungal Disease [Phase 2]
Phase 2 trial update comparing twice-weekly intravenous micafungin pharmacokinetics to daily dosing in patients at risk for invasive fungal …
-
CLINICAL_TRIALS trial_result · 2020-11-20Clinical Trial Update: Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCT [Phase 2]
Phase 2 trial comparing cyclophosphamide to anti-thymocyte globulin for GVHD prophylaxis after reduced-intensity conditioning allogeneic ste…
-
CLINICAL_TRIALS trial_result · 2020-11-12Clinical Trial Update: Ofatumumab as Primary Therapy of Chronic Graft Versus Host Disease [Phase 1, Phase 2]
A Phase 1/2 study evaluating ofatumumab as primary therapy for chronic graft-versus-host disease has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2020-10-01Clinical Trial Update: Prophylaxis Roles of IL-2 Treatment on GVHD After Transplantation [Phase 2]
Phase 2 trial update exploring prophylactic IL-2 treatment to prevent or mitigate acute graft-versus-host disease after transplantation.
-
CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Anti-thymocyte Globulins for Graft-versus-host Disease Prophylaxis [Phase 4]
Phase 4 trial update on anti-thymocyte globulins for graft-versus-host disease prophylaxis completed.
-
CLINICAL_TRIALS trial_result · 2020-09-11Clinical Trial Update: Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Participants With Steroid Refractory Acute Graft Versus Host Disease [Phase 3]
Phase 3 trial of methoxsalen with extracorporeal photopheresis for pediatric steroid-refractory acute graft-versus-host disease; study termi…