Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Early Access Program With MaaT013 in Steroid-refractory Acute Gastrointestinal Graft Versus Host Disease
Clinical trial update on MaaT013 for an Early Access Program in steroid-refractory acute graft-versus-host disease of the intestine. The spo…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: A Study to Compare T-Guard vs Ruxolitinib for Treatment of Steroid-Refractory Acute Graft-vs-Host Disease (BMT CTN 2002) [Phase 3]
A Phase 3 study comparing T-Guard vs ruxolitinib for steroid-refractory acute graft-versus-host disease has been terminated, with results po…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Chimeric Natural Killer Receptor-Universal T Cells for Refractory GVHD [Phase 1]
A Phase 1 trial evaluating Chimeric Natural Killer Receptor-Universal T Cells for refractory graft-versus-host disease is currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD [Phase 1, Phase 2]
Update on a Phase 1/2 dose-finding trial of pentostatin for injection for steroid-refractory acute graft-versus-host disease; the study is t…
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease [EARLY_Phase 1]
This early-phase 1 study evaluated the safety and potential effects of 5% lifitegrast ophthalmic solution in subjects with dry eye disease a…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases [Phase 2]
Phase 2 clinical trial evaluating a CD25 monoclonal antibody–containing GVHD prophylaxis to reduce severe acute GVHD after umbilical cord bl…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Effect of PMSCs and Their Secretome for the Treatment of GvHD [Phase 3]
A Phase 3 study evaluated placental mesenchymal stem cells (PMSCs) and their secretome for the treatment of graft-versus-host disease; the t…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease [Phase 1]
This Phase 1 clinical trial evaluated abatacept as prophylaxis against graft-versus-host disease after hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host Disease [Phase 1]
A Phase 1 trial evaluating Itacitinib in combination with Tocilizumab for steroid-refractory acute graft-versus-host disease has been termin…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell Transplantation [NA]
A clinical trial evaluating telmisartan to prevent acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation …
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Donor Neutrophil Subsets to Predict the Risk of aGVHD
A clinical trial at Nanfang Hospital/Southern Medical University is evaluating whether donor neutrophil subsets can predict the risk of acut…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating RGI-2001 to prevent acute graft-versus-host disease in patients after allogeneic hematopoietic stem cell transplant…
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: Efficacy and Safety of Anti-CD25 rhMAb in the Treatment of Steroid-Refractory cGVHD [Phase 4]
Phase 4 trial update evaluating efficacy and safety of anti-CD25 rhMAb for steroid-refractory chronic graft-versus-host disease (cGVHD).
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Extracorporeal Photopheresis and Low Dose Aldesleukin in Treating Patients With Steroid Refractory Chronic Graft-Versus-Host Disease [Phase 2]
Phase 2 trial evaluating extracorporeal photopheresis plus low-dose aldesleukin for steroid-refractory chronic graft-versus-host disease has…
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CLINICAL_TRIALS trial_result · 2024-03-28Clinical Trial Update: Prophylaxis of Graft-versus-host Disease With Anti-CD25 Antibody in Patients Underwent HSCT [Phase 2]
Phase 2 clinical trial evaluating anti-CD25 antibody for prophylaxis of graft-versus-host disease in patients undergoing hematopoietic stem …
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib [Phase 2]
A Phase 2 clinical trial investigating donor regulatory T-cells for chronic graft-versus-host disease in patients who do not achieve complet…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: A Study of Acute Graft-Versus-Host Disease (GVHD) in Patients Undergoing Allogeneic Stem-Cell Transplantation [Phase 2]
Phase 2 trial in acute graft-versus-host disease after allogeneic stem-cell transplantation was terminated; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment [Phase 1, Phase 2]
Clinical trial update on sequential administration of WJ-MSCs for graft-versus-host disease refractory to second-line treatment (Phase 1/Pha…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: A Study of Jaktinib for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease. [Phase 2]
Phase 2 clinical trial update for Jaktinib in the treatment of steroid-refractory acute graft-versus-host disease (aGVHD).
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease [Phase 3]
A Phase 3 clinical trial evaluating ruxolitinib as add-on therapy for steroid-refractory graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD [Phase 3]
Phase 3 clinical trial assessing safety and efficacy of iguratimod for chronic graft-versus-host disease (cGVHD).
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CLINICAL_TRIALS trial_result · 2024-01-22Clinical Trial Update: Itacitinib (INCB039110) and Extracorporeal Photopheresis (ECP) for First-Line Treatment in Chronic GVHD [Phase 2]
Phase 2 trial update for itacitinib (INCB039110) with Extracorporeal Photopheresis in first-line chronic graft-versus-host disease has been …
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CLINICAL_TRIALS trial_result · 2024-01-19Clinical Trial Update: To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids [Phase 3]
A Phase 3 trial update protocol comparing addition of methotrexate to standard corticosteroid-first-line treatment for acute graft-versus-ho…
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: Dexamethasone Solution and Dexamethasone in Mucolox™ [Phase 2]
Phase 2 trial updates for Dexamethasone Solution and Dexamethasone in Mucolox show completed status with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Study of Pregnyl as Adjunct Therapy for High-Risk or Refractory Acute GVHD [Phase 1, Phase 2]
Phase 1/2 trial evaluating Pregnyl as adjunct therapy for high-risk or refractory acute graft-versus-host disease has completed; results pos…