Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease [NA]
A clinical trial evaluating Tangible Boost for Stevens-Johnson Syndrome, Sjögren's syndrome, and eye-related graft-versus-host disease has b…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial evaluating leflunomide for chronic musculoskeletal graft-versus-host disease after allogeneic stem cell transplanta…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone [Phase 3]
A Phase 3 trial evaluated Alpha-1 Antitrypsin (AAT) plus corticosteroids versus corticosteroids alone for graft-versus-host disease in hemat…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals [NA]
A clinical trial (ImmunoCARE) evaluated rapid, accurate COVID-19 testing to reduce hospitalizations among immunocompromised individuals. The…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis [Phase 2]
A Phase 2 trial evaluating high-dose thymoglobulin with low-dose thymoglobulin as GVHD prophylaxis, substituting cyclosporine; the study NCT…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Lipopolysaccharide Metabolism and Identification of Potential Biomarkers Predictive of Graft-versus-host Disease After Allogeneic Stem Cell Transplantation [NA]
A completed trial update investigates lipopolysaccharide metabolism and identifies potential biomarkers that may predict graft-versus-host d…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: T Lymphocytes (LT) Expressing iCASP9 and ΔCD19 in Allogeneic Haematopoietic Transplantation. [Phase 1, Phase 2]
Phase 1/2 trial update on T lymphocytes engineered to express iCASP9 and ΔCD19 for allogeneic hematopoietic transplantation; the study statu…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT [Phase 2]
This Phase 2 trial comparing post-transplant cyclophosphamide (PTCy) plus ruxolitinib versus PTCy with tacrolimus and MMF in matched related…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Tildrakizumab for Prevention of Acute Graft-Versus-Host Disease [Phase 2]
Phase 2 trial evaluating tildrakizumab for prevention of acute graft-versus-host disease in patients with hematologic malignancies has compl…
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major [Phase 4]
Phase 4 trial evaluating Basiliximab to prevent acute graft-versus-host disease after unrelated donor hematopoietic stem cell transplantatio…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR) [Phase 3]
A Phase 3 trial evaluating itolizumab in combination with corticosteroids for first-line acute graft-versus-host disease was terminated.
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Infliximab Efficacy, TDM and Serum TNFα Levels in Pediatric HSCT Recipients With aGVHD: Prospective Observational Study
A completed prospective observational study in pediatric hematopoietic stem cell transplant recipients with acute graft-versus-host disease …
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Tacrolimus Blood Concentration and Transplant-related Outcomes in Pediatric HSCT Recipients
A completed pediatric hematopoietic stem cell transplant trial assessing how tacrolimus blood concentration relates to transplant-related ou…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Ruxolitinib With Calcineurin Inhibitor and Methotrexate vs. Calcineurin Inhibitor Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation [NA]
This completed clinical trial compares ruxolitinib-based graft-versus-host disease prophylaxis (with a calcineurin inhibitor and methotrexat…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: MTX and Steroid as First-line Therapy for aGVHD [Phase 3]
Phase 3 trial evaluating methotrexate plus steroids as first-line therapy for acute graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Treatment Safety and Efficacy of Pro-ocular™ 1% for Chronic Ocular Graft Following Allogeneic HSCT. [Phase 2]
A Phase 2 trial assessing the safety and efficacy of Pro-ocular 1% for chronic ocular graft-versus-host disease has completed and results ha…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213 [Phase 2]
A phase 2 update reports extended treatment and follow-up data for belumosudil in KD025-208 and KD025-213 for chronic graft-versus-host dise…
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease
This ClinicalTrials.gov entry describes a study evaluating CXCL9 and EASIX as predictors for acute graft-versus-host disease, currently recr…
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Expressive Writing in GVHD [EARLY_Phase 1]
This clinical trial update reports that a Phase 1 early study examining expressive writing as an intervention for Graft Versus Host Disease …
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study to Assess the Safety and Pharmacokinetics of GDC-8264 in Combination With Standard of Care in Participants With Acute Graft-Versus-Host Disease (aGVHD) [Phase 1]
This Phase 1 study evaluates the safety and pharmacokinetics of GDC-8264 in combination with standard of care in participants with acute gra…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: The Safety and Efficacy of Fecal Microbiota Transplant (FMT) for Steroid-refractory Graft-versus-host Disease [NA]
Completed clinical trial update evaluating the safety and efficacy of fecal microbiota transplant for steroid-refractory graft-versus-host d…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD [Phase 1, Phase 2]
This clinical trial update reports a completed Phase 1/2 study evaluating EQ001 in patients with acute graft-versus-host disease, including …
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 study evaluating activity, safety, and pharmacokinetics of a therapy in pediatric patients with moderate to severe chronic graft-ver…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease [Phase 2]
This clinical trial update describes a Phase 2 study evaluating extracorporeal photopheresis with UVADEX plus standard steroids for high-ris…