Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD [Phase 1]
A Phase 1 trial update describes evaluating a combination of ruxolitinib and fostamatinib for steroid-refractory chronic graft-versus-host d…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease [Phase 3]
This report provides an update on a Phase 3 trial evaluating Axatilimab as monotherapy in Japanese participants with recurrent or refractory…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Efficacy of Low-dose PT-Cy for Prevention of GVHD in Ambulatory Allogeneic HSCT [Phase 2]
Phase 2 trial results assess the efficacy of low-dose post-transplant cyclophosphamide for preventing graft-versus-host disease in ambulator…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: UCMSCs as Front-line Approach of Treatment for Patients With aGVHD [Phase 1, Phase 2]
Clinical trial update reporting completion of a Phase 1/2 study evaluating umbilical cord-derived mesenchymal stem cells as first-line thera…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease
This clinical trial update indicates that NCT03438643, studying immunocompetent populations treated with extracorporeal photopheresis for ch…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Efficacy and Safety of Nilotinib in Patients With a Chronic Disease of the Graft Against the Host [Phase 2]
A Phase 2 clinical trial assessing the efficacy and safety of nilotinib in patients with chronic graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: UVB Phototherapy Treatment of Oral Chronic GVHD [Phase 2]
Phase 2 trial evaluating UVB phototherapy for oral chronic graft-versus-host disease has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib [Phase 2]
This clinical trial update describes a Phase 2 rollover study of Itacitinib to provide continued treatment for participants previously enrol…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: The Oral cGVHD as a Predictive Factor of Graft Versus Leukaemia Effect in Patients Who Received an Allograft
This clinical trial update reports on whether oral chronic graft-versus-host disease can predict the graft-versus-leukemia effect in allogen…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Detection of Graft Versus Host Disease With [18F]F-AraG [Phase 1]
Phase 1 trial evaluating the PET imaging agent [18F]F-AraG for detecting graft-versus-host disease; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Study of TQ05105 Tablets in Subjects With Glucocorticoid-Refractory Acute Graft-Versus-Host Disease (aGVHD) [Phase 1, Phase 2]
A Phase 1/Phase 2 study of TQ05105 tablets for glucocorticoid-refractory acute graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias [Phase 2]
A Phase 2 trial of fostamatinib for immune-mediated anemia, immune-mediated thrombocytopenia, and chronic graft-versus-host disease after he…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of TQ05105 in Patients With Chronic Graft Versus Host Disease [Phase 1, Phase 2]
Phase 1/2 study of TQ05105 for chronic graft-versus-host disease, with the trial currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Effects of Omega-3 Fatty Acids on Acute Graft-versus-Host Disease After Allogeneic Stem Cell Transplantation. [Phase 1, Phase 2]
A clinical trial update shows omega-3 fatty acids are being studied for their effects on acute graft-versus-host disease following allogenei…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Psychosocial Mobile App for Chronic Graft-Versus-Host Disease [NA]
This clinical trial update notes a psychosocial mobile app being studied for chronic graft-versus-host disease; the study is currently activ…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease [Phase 2]
This Phase 2 trial update evaluates acalabrutinib for chronic graft-versus-host disease. The study is active but not currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Safety and Efficacy of Prochymal for the Salvage of Treatment-Refractory Acute GVHD Participants [Phase 2]
Phase 2 trial update evaluating Prochymal for salvage therapy in treatment-refractory acute graft-versus-host disease, reporting safety and …
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib. [Phase 4]
This Phase 4 trial update describes extending ibrutinib treatment for patients who continue to benefit from the therapy.
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD) [Phase 1, Phase 2]
This update reports on a completed Phase 1/2 dose-finding and safety study of ibrutinib in pediatric patients with chronic graft-versus-host…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Proof-of-concept Trial of Apraglutide in Acute Graft Versus Host Disease (aGVHD) [Phase 2]
Phase 2 proof-of-concept trial of apraglutide in acute graft-versus-host disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Treatment Use of the CliniMACS® CD34 TCR Alpha/Beta for Allogenic Transplant (Expanded Access Use)
Clinical trial update describing expanded access use of CliniMACS CD34 TCR Alpha/Beta for allogeneic transplantation.
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease. [Phase 3]
Phase 3 trial update for belumosudil in combination with corticosteroids in newly diagnosed chronic graft-versus-host disease; the study is …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Close Assessment and Testing for Chronic Graft Versus Host Disease, CATCH Study
Update on the CATCH study evaluating close assessment and testing for chronic graft-versus-host disease. The trial status is completed.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD)) [Phase 1, Phase 2]
An update on the Phase 1/2 trial of TDI01 for chronic graft-versus-host disease, noting a recruitment suspension and current status as activ…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Prevention of GVHD in Patients Treated With Allogeneic SCT: Possible Role of Extracorporeal Photophoresis [NA]
A completed clinical trial evaluating whether extracorporeal photopheresis can prevent graft-versus-host disease in patients undergoing allo…