Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Theralux Extracorporeal Photochemotherapy (ECP) in Patients With Extensive Chronic Graft Versus Host Disease (GvHD) [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial of Theralux Extracorporeal Photochemotherapy (ECP) for extensive chronic graft-versus-host disease has comp…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Rituximab for the Primary Treatment of Denovo Extensive Chronic Graft Versus Host Disease (GVHD) [Phase 2]
This document summarizes a Phase 2 trial evaluating rituximab as the primary treatment for extensive chronic graft-versus-host disease (GVHD…
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: Multi Donor Mismatched Stem Cell Transplantation (MDT) [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study of multi-donor mismatched stem cell transplantation for graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Blood and Marrow Transplant Clinical Research Network [NA]
The Blood and Marrow Transplant Clinical Research Network study has completed, summarizing transplantation approaches across hematologic dis…
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: 70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 [NA]
This clinical trial evaluated using 70% ethanol to decontaminate central venous lines exposed to calcineurin inhibitors in patients undergoi…
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Efficacy and Safety Study of Budesonide to Treat Oral Chronic Graft vs Host Disease (cGvHD) [Phase 3]
A Phase 3 trial evaluating budesonide for efficacy and safety in oral chronic graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Comparison of Two Automated Mononuclear Collection Systems in Patients Undergoing Extracorporeal Photochemotherapy. A Cross-over Equivalence Study. (MNC_CMNC) [Phase 3]
A Phase 3 cross-over trial comparing two automated mononuclear cell collection systems used during extracorporeal photochemotherapy in patie…
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye [Phase 2]
Phase 2 trial comparing thymosin beta-4 eye drops to vehicle for severe dry eye, including Sjögren's syndrome; results were posted in 2015 a…
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer [Phase 2]
Phase 2 trial assessing low-intensity stem cell transplantation with multiple lymphocyte infusions for advanced kidney cancer (renal cell ca…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Photochemotherapy and Graft-versus-leukemia in Acute-leukemia
This clinical trial update reports a completed study from Karolinska University Hospital evaluating photochemotherapy to enhance graft-versu…
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD [NA]
Completed Mayo Clinic trial evaluated intense pulsed light and Meibomian gland expression for treating ocular rosacea and ocular GVHD, with …
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitis [Phase 2]
Phase 2 trial evaluating topical thalidomide for chronic graft-versus-host-disease–related stomatitis; the study was terminated and results …
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: Treatment of Ocular Graft-versus-Host Disease (GVHD) With Topical Loteprednol Etabonate 0.5% [NA]
This completed trial assessed topical loteprednol etabonate 0.5% for ocular graft-versus-host disease presenting with dry eyes; results were…
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host Disease [Phase 2]
Phase 2 trial comparing tacrolimus and sirolimus with or without ustekinumab for prevention of acute graft-versus-host disease has completed…
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: The Effect of Folinic Acid Rescue Following MTX GVHD Prophylaxis on Regimen Related Toxicity and Transplantation Outcome [Phase 2, Phase 3]
Phase 2/3 clinical trial update investigating folinic acid rescue after methotrexate-based GVHD prophylaxis to reduce regimen-related toxici…
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CLINICAL_TRIALS trial_result · 2015-07-20Clinical Trial Update: Graft-Versus-Host Disease in Treating Patients With Recurrent or Refractory Lymphoma or Hodgkin's Disease [Phase 3]
A Phase 3 trial investigating treatment for graft-versus-host disease in patients with recurrent or refractory lymphoma or Hodgkin's disease…
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CLINICAL_TRIALS trial_result · 2015-06-23Clinical Trial Update: Extended Use of Cannabidiol for the Prevention of Graft-versus-host-disease [Phase 2]
This is an update on a Phase 2 clinical trial evaluating extended use of cannabidiol to prevent graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Open-Label Study Designed to Evaluate the Safety and Preliminary Efficacy of ApoCell for the Prevention of Acute GvHD [Phase 1, Phase 2]
An open-label Phase 1/2 study is evaluating ApoCell for the prevention of acute graft-versus-host disease. The update notes safety and preli…
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Infliximab for the Prevention of Graft-versus-Host Disease Following Allogenic Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial update reports completion of a study evaluating infliximab for preventing graft-versus-host disease after allogenei…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Alefacept for Chronic Graft Versus Host Disease [Phase 1, Phase 2]
Clinical trial update reporting the completion of Phase 1 and Phase 2 studies of alefacept for resistant chronic graft-versus-host disease.
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: A Study to Evaluate the Effect of ATG-F on Engraftment, Graft Versus Host Disease (GVHD) and Graft Versus Leukemia (GVL) Effect in Haplo-identical SCT [Phase 3]
Phase 3 study evaluating ATG-F for engraftment, graft-versus-host disease, and graft-versus-leukemia effects in haplo-identical stem cell tr…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Alefacept for Prevention of Graft Versus Host Disease (GVHD) [Phase 3]
Phase 3 clinical trial evaluating alefacept to prevent graft-versus-host disease was terminated.
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Intra Arterial (IA) Steroids Infusion for Hepatic Acute Hepatic Graft Versus Host Disease (aGVHD) [NA]
A clinical trial evaluating intra-arterial steroid infusion for hepatic acute graft-versus-host disease has been terminated.
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation [Phase 3]
Phase 3 randomized trial comparing sirolimus plus tacrolimus versus cyclosporine plus methotrexate for graft-versus-host disease prophylaxis…
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Tear Cytokine Analysis as a Prediction or Diagnostic Marker in Ocular GvHD
The trial evaluated tear cytokines as a potential predictor or diagnostic marker for ocular graft-versus-host disease, and the study has com…