Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Donor Th2 Cells to Prevent Graft-Versus-Host Disease in Bone Marrow Transplants [Phase 1]
Phase 1 clinical trial evaluating donor T-helper 2 (Th2) cell therapy to prevent graft-versus-host disease after bone marrow transplantation…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Photopheresis for the Treatment of Acute Graft Versus Host Disease [Phase 2]
Phase 2 trial update evaluating extracorporeal photopheresis for acute graft-versus-host disease; completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of Ponesimod in Subjects With Symptomatic Chronic GVHD [Phase 2]
Phase 2 study evaluating the biological activity, safety, tolerability, and pharmacokinetics of ponesimod in symptomatic chronic graft-versu…
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis [Phase 4]
Phase 4 clinical trial update on using antithymocyte globulin for prophylaxis of acute graft-versus-host disease in haploidentical hematopoi…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer [Phase 2]
Phase 2 clinical trial evaluating busulfan, cyclophosphamide, and antithymocyte globulin followed by stem cell transplant for hematologic ca…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT [Phase 1]
Phase I trial of LDE225 (sonidegib) for steroid-refractory chronic graft-versus-host disease after allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS trial_result · 2018-03-06Clinical Trial Update: A Phase 1/2 Trial of Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-Host-Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor regulatory T-cells for treatment of chronic graft-versus-host disease refractory to steroids.
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Pomalidomide for Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 clinical trial of pomalidomide for chronic graft-versus-host disease has completed and posted results.
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: A Pilot Study of Alpha-1-Antitrypsin (AAT) in Steroid Refractory Acute Graft vs Host Disease [Phase 2]
Phase 2 pilot study of alpha-1-antitrypsin for steroid-refractory acute graft-versus-host disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-01-02Clinical Trial Update: Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating vorinostat with tacrolimus and methotrexate to prevent graft-versus-host disease after unrelated stem cell transpla…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases [Phase 1]
Phase 1 trial evaluating the safety of Umbilical Cord Blood T-Regulatory Cell infusion followed by donor cord blood transplant in patients w…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host Disease [NA]
Phase 2 trial evaluating rituximab plus corticosteroid therapy as initial treatment for newly diagnosed chronic graft-versus-host disease; r…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Skin Disease and Pulmonary Mortality After Transplantation
A completed clinical trial update reporting on skin disease and pulmonary mortality after transplantation, focusing on acute graft-versus-ho…
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: A Phase 2A Study of ALXN1007 in Participants With Newly Diagnosed Acute Lower Gastrointestinal Graft-Versus-Host Disease [Phase 2]
Phase 2A study of ALXN1007 for newly diagnosed acute lower gastrointestinal graft-versus-host disease (GVHD) was terminated; results posted …
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CLINICAL_TRIALS trial_result · 2017-09-05Clinical Trial Update: Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT) [Phase 2]
Phase II study of Tocilizumab for glucocorticoid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transpl…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Donor Atorvastatin Treatment for Preventing Severe Acute Graft-Versus-Host Disease in Patients Undergoing Myeloablative Peripheral Blood Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating donor atorvastatin to prevent severe acute graft-versus-host disease in patients undergoing myeloablative periphera…
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease [Phase 2]
Phase 2 trial assessing safety and efficacy of photopheresis plus standard therapy for chronic graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease [Phase 2]
Phase 2 study evaluating photopheresis with UVADEX to prevent graft-versus-host disease after transplantation has completed.
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease [Phase 3]
A Phase 3 trial evaluating extracorporeal photoimmune therapy with UVADEX (amotosalen) for acute graft-versus-host disease was terminated.
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CLINICAL_TRIALS trial_result · 2017-07-18Clinical Trial Update: Standard of Care vs. Bortezomib in Graft-Versus Host Disease After Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 trial comparing standard of care versus bortezomib for graft-versus-host disease after hematopoietic stem cell transplantation; the …
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Bandage Lenses in Treating Patients With Ocular Graft-Versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluated bandage contact lenses for treating ocular complications in graft-versus-host disease, with results poste…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis [Phase 2]
A Phase 2 trial of in vivo regulatory T cell expansion for prophylaxis of graft-versus-host disease has completed, with results posted in Ju…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Cyclosporine Implant for Ocular Graft-Versus-Host Disease [Phase 1]
A Phase 1 trial evaluating a cyclosporine implant for ocular graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Extracorporeal Photopheresis to Treat Chronic Graft-Versus-Host Disease [Phase 2]
This clinical trial update reports completion of a Phase 2 study evaluating extracorporeal photopheresis for chronic graft-versus-host disea…
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT [Phase 4]
A Phase 4 trial suggests that reducing the dose of anti-thymoglobulin (ATG) lowers chronic graft-versus-host disease without raising leukemi…