Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-04-24Clinical Trial Update: A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD [Phase 2, Phase 3]
Phase 2/3 trial of GLASSIA for acute graft-versus-host disease (GvHD) was terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Low Dose ATG Plus Low Dose PTCy as GVHD Prophylaxis in Haplo-HSCT [Phase 2]
A Phase 2 clinical trial evaluates low-dose ATG plus low-dose PTCy as graft-versus-host disease prophylaxis in haploidentical hematopoietic …
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CLINICAL_TRIALS trial_result · 2019-04-05Clinical Trial Update: Ruxolitinib for Steroid-refractory GVHD [Phase 2]
A Phase 2 clinical trial evaluating ruxolitinib for steroid-refractory graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2019-04-05Clinical Trial Update: Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease [Phase 2]
Phase 2 trial evaluating infliximab and basiliximab for steroid-refractory acute graft-versus-host disease; study terminated with results po…
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CLINICAL_TRIALS trial_result · 2019-03-20Clinical Trial Update: Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD) [Phase 3]
A Phase 3 trial evaluating US-ATG-F to prevent chronic graft-versus-host disease in hematologic malignancy patients has completed with resul…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer [Phase 2]
Phase 2 trial investigating rituximab to prevent acute graft-versus-host disease in donor stem cell transplantation for hematologic cancers;…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Vulvovaginal Graft Versus Host Disease (VV-GVHD) in Women Who Underwent Transplantation Before and After Menarche
The clinical trial update reports on a completed study examining vulvovaginal graft-versus-host disease (VV-GVHD) in women who underwent tra…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis [NA]
This clinical trial update describes a study of minor salivary gland transplantation for cicatricial conjunctivitis, sponsored by National T…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Carfilzomib in Treating Patients With Chronic Graft-Versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluating carfilzomib for chronic graft-versus-host disease has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Ixazomib Citrate in Treating Patients With Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluated ixazomib citrate for chronic graft-versus-host disease; the study has completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Comparison of Gut Microbiota, Inflammation and Symptoms Following Allogeneic HSCT
Completed clinical trial investigating gut microbiota, inflammation, and symptoms following allogeneic hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT) [NA]
Clinical trial update on the safety of post-transplant alpha-beta depleted T-cell infusion after haploidentical stem cell transplantation; r…
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CLINICAL_TRIALS trial_result · 2018-12-26Clinical Trial Update: Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD) [Phase 2]
Phase 2 trial investigating entospletinib with systemic corticosteroids as first-line therapy for chronic graft-versus-host disease; study t…
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell Transplant [NA]
Clinical trial update on low-dose total lymphoid irradiation for refractory chronic graft-versus-host disease after donor stem cell transpla…
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Lactobacillus Rhamnosus GG in Reducing Incidence of Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant [NA]
Clinical trial assessing Lactobacillus rhamnosus GG to reduce graft-versus-host disease in patients after donor stem cell transplantation ha…
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Alpha 1 Antitrypsin (AAT) for acute graft-versus-host disease (GVHD) after transplantation; study comple…
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CLINICAL_TRIALS trial_result · 2018-10-18Clinical Trial Update: A Phase II Trial of Low-Dose Interleukin-2 (IL-2) Added to Extra-Corporeal Photopheresis for Steroid-Refractory cGVHD [Phase 2]
Phase II study evaluating the addition of low-dose interleukin-2 to extracorporeal photopheresis for steroid-refractory chronic graft-versus…
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
Clinical trial update for nonmyeloablative conditioning and transplantation in refractory systemic lupus erythematosus (SLE) has terminated;…
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers [Phase 2]
Phase 2 trial evaluating cyclosporine with T-cell add-back in blood cell transplant settings for hematologic cancers, including chronic lymp…
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CLINICAL_TRIALS trial_result · 2018-09-14Clinical Trial Update: High-Dose Cyclophosphamide for Steroid Refractory GVHD [Phase 2]
Phase 2 trial investigating high-dose cyclophosphamide for steroid-refractory graft-versus-host disease has completed with results posted in…
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801) [Phase 2, Phase 3]
Phase 2/3 trial update for chronic graft-versus-host disease treatment completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: A Study Comparing Corticosteroids Alone Versus Corticosteroids and Extracorporal Photopheresis (ECP) as First-line Treatment of Standard II Acute Graft-versus-host Disease [Phase 2]
A Phase 2 study comparing corticosteroids alone versus corticosteroids with extracorporeal photopheresis as first-line treatment for standar…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Brentuximab Vedotin for Steroid Refractory GvHD [Phase 1]
A Phase 1 study evaluating brentuximab vedotin for steroid-refractory graft-versus-host disease has completed.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Phase I Trial of Brentuximab Vedotin for Refractory Chronic Graft-vs.-Host Disease (GVHD) [Phase 1]
Phase I trial of brentuximab vedotin for refractory chronic graft-versus-host disease has been terminated; the study was conducted at Massac…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease [Phase 2]
Open-label Phase II study evaluating topical sirolimus for refractory oral chronic graft-versus-host disease; the trial has been terminated …