Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies [Phase 4]
Phase 4 study evaluating pharmacokinetics, efficacy, and safety of Belumosudil in Chinese adolescents with chronic graft-versus-host disease…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease [Phase 2]
A Phase II randomized trial is comparing decidual stromal cells to the best available treatment for graft-versus-host disease. The study is …
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Autologous Serum Obtained by a Closed-Circuit Collection Device [Phase 2]
Phase 2 clinical trial evaluating autologous serum obtained by a closed-circuit collection device for several ocular surface diseases; recru…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Gecacitinib for cGVHD: Safety and Efficacy in Patients After ≥2 Lines of Prior Therapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of gecacitinib for chronic graft-versus-host disease in patients with at least…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Dapagliflozin in Allo-HCT for aGVHD [Phase 2]
A Phase 2 clinical trial is evaluating dapagliflozin for acute graft-versus-host disease after allogeneic stem cell transplantation, and the…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD [Phase 3]
A Phase 3 trial evaluating mini-dose methotrexate in combination with standard-dose steroids as initial treatment for acute graft-versus-hos…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant [Phase 1]
Phase 1 trial evaluating emapalumab with post-transplant cyclophosphamide, tacrolimus and mycophenolate mofetil to prevent graft-versus-host…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease [Phase 2]
A Phase 2 clinical trial evaluating Axatilimab in combination with extracorporeal photopheresis for chronic graft-versus-host disease (cGVHD…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: ATG Plus PTCy vs ATG for CGVHD Prophylaxis [Phase 2]
Phase 2 trial comparing ATG plus post-transplant cyclophosphamide versus ATG for prophylaxis of chronic graft-versus-host disease in patient…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Pediatric GVHD Low Risk Steroid Taper Trial [Phase 2]
Phase 2 pediatric trial evaluating a low-risk steroid taper strategy for acute graft-versus-host disease in allogeneic bone marrow transplan…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Study of iMSC for the Prevention of Acute Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
Early-phase clinical trial evaluating iMSC to prevent acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantati…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: A Trial to Evaluate the Safety and Efficacy of NCR102 in Subjects With aGVHD [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating NCR102 for safety and efficacy in subjects with acute graft-versus-host disease; the study status is N…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) [Phase 1]
Phase 1 clinical trial assessing a preventive therapy to reduce graft-versus-host disease in participants with hematologic malignancies unde…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Efficacy of Human Chorionic Gonadotropin in Acute GVHD Treatment [Phase 2]
Phase 2 clinical trial evaluating the efficacy of human chorionic gonadotropin for treating acute graft-versus-host disease.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: The Skin Microbiome in Graft Versus Host Disease
A ClinicalTrials.gov update indicates an active, not recruiting study sponsored by University Hospital Basel examining the skin microbiome i…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Vaginal Microbiome and the Development of Vulvovaginal Graft Versus Host Disease
This clinical trial update describes a study on the vaginal microbiome and the development of vulvovaginal graft-versus-host disease in pati…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: FMT in Gut aGVHD Treated
A clinical trial is evaluating fecal microbiota transplantation for gut involvement in acute graft-versus-host disease and is currently recr…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: The Application of Novel Identified CD8 Regulatory Precursors in Inducing Immune Tolerance After Allo-HSCT
The study investigates novel CD8 regulatory precursor therapy to induce immune tolerance after allogeneic hematopoietic stem cell transplant…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moderate or Higher Severity [Phase 2]
A Phase 2 trial assesses whether adding ruxolitinib to steroids as initial therapy improves outcomes in moderate-or-higher chronic graft-ver…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease [Phase 2]
A Phase 2 clinical trial of TQ05105 tablets for chronic graft-versus-host disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: IRENE-G Study: Impact of Resistance Exercise and Nutritional Endorsement on GvHD Symptoms [NA]
Clinical trial update for the IRENE-G study evaluating resistance exercise and nutritional endorsement on graft-versus-host disease symptoms…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host Disease [NA]
Clinical trial update indicates that a study evaluating water-filtered infrared-A (wIRA) radiation for Morphea and sclerotic graft-versus-ho…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease
A completed clinical study update examining microRNA expression in acute graft-versus-host disease in patients receiving allogeneic stem cel…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Universal CNK-UT Therapy for Refractory aGVHD [Phase 1]
A Phase 1 clinical trial update for Universal CNK-UT Therapy targeting refractory acute graft-versus-host disease. The study is currently re…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Post-Transplant Cyclophosphamide, Bortezomib and Abatacept for the Prevention of Graft-versus-Host-Disease (GvHD) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating post-transplant cyclophosphamide, bortezomib, and abatacept to prevent graft-versus-host disease is curr…