Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease
This clinical trial update describes a study using dendritic cell therapy in patients with acute or chronic skin graft-versus-host disease (…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation
This clinical trial update describes a study evaluating the kinetics of immune cells in blood and tissues affected by chronic graft-versus-h…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Disease [Phase 1]
Phase 1 clinical trial investigating fecal microbiota transplant and dietary fiber for treating intestinal graft-versus-host disease. The tr…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial [NA]
A clinical trial update for the RESTART trial assessing the impact of exercise on corticosteroid-related complications in patients with graf…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation
This clinical trial is currently recruiting to study diagnosis methods and microbiome factors in vulvovaginal graft-versus-host disease, a G…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Ocular Complications From Cancer Therapy - Patient Registry and Biobank
This clinical trial update describes a patient registry and biobank investigating ocular complications from cancer therapy, including graft-…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Vitamin C With Steroids for Gastrointestinal GVHD [EARLY_Phase 1]
A Baylor College of Medicine–led early-phase trial (NCT07197749) is evaluating vitamin C with steroids for gastrointestinal graft-versus-hos…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD) [Phase 4]
Phase 4 clinical trial to evaluate the safety of Belumosudil in participants aged 12 years and older with chronic graft-versus-host disease;…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease [NA]
The update indicates a multicenter trial evaluating multidisciplinary interventions for adults with chronic graft-versus-host disease that i…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood [Phase 2]
Phase 2 clinical trial evaluating co-transplant of an unmodified haplo-identical graft with cord blood; the study targets acute graft-versus…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Efficacy and Safety of Gecacitinib Hydrochloride in Prophylaxis Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelofibrosis [NA]
A clinical trial evaluating gecacitinib hydrochloride for prophylaxis of acute graft-versus-host disease after allogeneic hematopoietic stem…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: PTCY Plus uhCG/EGF for Graft Versus Host Disease Prophylaxis [Phase 1]
A Phase 1 clinical trial evaluating the combination of post-transplant cyclophosphamide (PTCY) with uhCG/EGF for prophylaxis of graft-versus…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis [Phase 2]
A Phase 2 clinical trial is evaluating whether extended dosing of abatacept is as effective as short-term dosing for preventing graft-versus…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP) [Phase 2]
A Phase 2 clinical trial BEBOP evaluating belumosudil for prevention and treatment of bronchiolitis obliterans syndrome and bronchiolitis ob…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia [Phase 1]
This entry reports a Phase 1 dose-escalation trial of mesenchymal stromal cells for medical xerostomia, including patients with graft-versus…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease [Phase 1]
This clinical trial is evaluating regulatory T-cell therapy in combination with low-dose interleukin-2 for steroid-refractory chronic graft-…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD [Phase 1, Phase 2]
An update on a Phase 1b/2 trial of axatilimab as monotherapy in Chinese participants with recurrent or refractory chronic graft-versus-host-…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: A Clinical Study on the Efficacy and Safety of Ivarmacitinib in Preventing aGVHD After HLA-matched Transplantation [Phase 1, Phase 2]
A clinical trial update for a phase 1/2 study evaluating the efficacy and safety of Ivarmacitinib to prevent acute graft-versus-host disease…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD [Phase 2]
Phase 2 clinical study evaluating cyclophosphamide, abatacept, and tacrolimus for prevention of graft-versus-host disease; the study is curr…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Cohort Study on the Association Between the ANS Function and Acute GvHD
This clinical trial update describes a cohort study examining the relationship between autonomic nervous system function and acute graft-ver…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating vorinostat to prevent graft-versus-host disease in children, adolescents, and young adults undergoi…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Fatigue and Cognitive Dysfunction Due to Synaptopathy or Graft Versus Host (GVH) Disease in the Brain.
A clinical trial at Karolinska University Hospital is recruiting to study fatigue and cognitive dysfunction associated with synaptopathy or …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation [Phase 2]
Phase 2 clinical trial evaluating a conditioning regimen with post-transplant GVHD prophylaxis using cyclophosphamide and methotrexate in pa…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases [NA]
This entry reports on a clinical trial evaluating patient-reported outcomes of UVA-1 phototherapy for treating sclerosing skin diseases, inc…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHD [Phase 2]
A Phase 2 trial is evaluating fecal microbiota transplantation for steroid-refractory acute gastrointestinal graft-versus-host disease; the …