Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas [Phase 1]
This Phase 1 clinical trial evaluates the feasibility of hyperpolarized 13C-pyruvate metabolic MRI for imaging infiltrating gliomas. The spo…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating fluoxetine in combination with cytotoxic lysosomal stress for glioma; the study is currently acti…
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CLINICAL_TRIALS other · 2025-09-18Clinical Trial Update: Assessing Brain Metabolism Using MRS With Deuterated Glucose
This clinical trial is evaluating brain metabolism in glioma patients using magnetic resonance spectroscopy with deuterated glucose. The stu…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Registering Genomics and Imaging of Tumors (ReGIT)
The ReGIT trial (Registering Genomics and Imaging of Tumors) is currently recruiting patients with glioma, sponsored by Indiana University.
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Protoporphyrin Imaging in Multispectral Evaluation of Resections [NA]
A clinical trial from Medical University Innsbruck is evaluating protoporphyrin-based imaging for multispectral assessment of glioma resecti…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression [Phase 2]
A Phase 2 safety study evaluating VAL-083 in combination with radiotherapy for newly diagnosed glioblastoma with unmethylated MGMT expressio…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting [Phase 2]
VAL-083 (dianhydrogalactitol) is being studied in MGMT unmethylated, bevacizumab-naive glioblastoma patients in the adjuvant or recurrent se…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
Kintara Therapeutics completed a Phase 1/2 safety study of VAL-083 in patients with recurrent malignant glioma, including glioma and gliobla…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Application of Cognitive Training Based on the Remind Strategy in Glioma Patients With Cognitive Impairment [NA]
A completed clinical trial study evaluating Remind Strategy-based cognitive training in glioma patients with cognitive impairment.
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Prognostic IntraOperative Biomarkers ideNtification in Tumor rElatEd suRgery [NA]
A ClinicalTrials.gov listing for a study at Erasmus Medical Center evaluating intraoperative biomarkers to predict prognosis during tumor-re…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas [Phase 2]
Phase 2 clinical trial evaluating retifanlimab and epacadostat with radiation and bevacizumab in recurrent gliomas has completed. Results ha…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: ERP-Based Research on the Modulation of Remimazolam on Working Memory and Brain Network Mechanisms in Glioma Patients [NA]
A clinical trial update describing ERP-based research on how remimazolam may affect working memory and brain networks in glioma patients; th…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Radiolabeled TSPO Targeted Molecular Probe in Glioma
A study evaluating a radiolabeled TSPO-targeted molecular probe for imaging glioma has been listed. The trial status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas [EARLY_Phase 1]
This early-phase 1 trial investigates vemurafenib in pediatric patients with recurrent/refractory BRAFV600E-mutant gliomas and has completed…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Phase I Study of HMPL-306 for the Treatment of Gliomas With IDH1 and/or IDH2 Mutations [Phase 1]
Hutchmed is conducting a Phase I trial of HMPL-306 for gliomas with IDH1 and/or IDH2 mutations, and the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)
The PEAR-GLIO trial evaluating an AI R&D tool for adult gliomas and other primary brain tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors [NA]
Completed clinical trial evaluating Blood-Brain Barrier Disruption (BBBD) for liquid biopsy in patients with glioblastoma or glioma, sponsor…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population
A completed clinical trial evaluating the validity and reliability of the PRO-CTCAE for adult-type diffuse glioma patients in the Chinese po…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: ASCENT Intervention for Brain Tumor Patients [NA]
Clinical trial update for the ASCENT intervention in brain tumor patients shows recruitment is ongoing. The study targets malignant brain tu…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma [NA]
A clinical trial update describes using molecular profiling to tailor treatments for patients with high-grade glioma, aiming to improve indi…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: LIQUID BIOPSY IN Low-grade Glioma Patients [NA]
Clinical trial evaluating liquid biopsy for patients with low-grade glioma is currently Recruiting at University Hospital, Montpellier.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma [Phase 2]
Phase 2 trial comparing proton beam therapy with intensity-modulated radiation therapy for preserving brain function in IDH-mutant grade II/…
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EMA approval · 2025-07-10EMA Authorised: Temozolomide Sun (temozolomide) — Sun Pharmaceutical Industries Europe B.V.
The European Medicines Agency has authorised Sun Pharmaceutical's temozolomide product for the treatment of glioma.
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: BC008-1A Injection for Recurrent CNS WHO G4 Glioma [Phase 1]
A Phase 1 study of BC008-1A Injection for recurrent central nervous system WHO Grade 4 glioma (including glioblastoma) is currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Blood Biomarker Signature in Glioma
The clinical trial investigating a blood biomarker signature in glioma has been terminated.