Glioma
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-08-18EMA Authorised: Temodal (temozolomide) — Merck Sharp & Dohme B.V.
Temodal (temozolomide) has been authorised in the EU for glioma.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Update: Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation [Phase 3]
Phase 3 trial update for vorasidenib (S095032/AG-881) in Asian participants with residual or recurrent Grade 2 IDH-mutant glioma; study stat…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma [NA]
Clinical trial evaluating hippocampal-avoidance using proton therapy in various low-grade gliomas; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment [Phase 2]
A Phase 2 clinical trial is testing Erdafitinib for recurrent glioma (including WHO grades 2–4) that has progressed after prior treatment; r…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared
A clinical trial update describing a study in low-grade gliomas evaluating patient-reported outcomes with vorasidenib in combination with ra…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Multimodal Machine Learning Characterization of Solid Tumors
This ClinicalTrials.gov update describes a multimodal machine learning study to characterize solid tumors, listing prostate cancer, hepatoce…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Prospective Study on Oncologic Cerebral Imagery Contribution by 18F-FDOPA Position Emission Tomography (PET) [NA]
This clinical trial update notes the completion of a prospective study evaluating the contribution of 18F-FDOPA PET imaging to oncologic cer…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. [Phase 1]
Pfizer's PF-07799933 is being studied in a Phase 1 trial for advanced solid tumors with BRAF alterations. The study includes melanoma, non-s…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors [Phase 1]
Pfizer is conducting a Phase 1 study of PF-07799544 as a monotherapy or in combination for advanced solid tumors, including melanoma and gli…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Chronic Convection Enhanced Delivery of Topotecan [Phase 1]
Phase 1 trial of chronic convection-enhanced delivery of topotecan for glioma has completed.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of LY3410738 in patients with IDH1/IDH2-mutant advanced solid tumors, including cholangiocarcinoma, chondrosarcoma, and glioma…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination of Tarlatamab with Temozolomide for glioma and other CNS tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Ultralow Dose PET Imaging of 18F-FDOPA [Phase 2]
Phase 2 trial evaluating ultralow-dose PET imaging with the radiotracer 18F-FDOPA in healthy volunteers and Parkinsonian syndromes to assess…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Sitagliptin in Recurrent/Progressive Grade 4 Glioma [Phase 1]
Clinical trial update describing a Phase 1 study of sitagliptin in recurrent or progressive glioma and glioblastoma, with status NOT_YET_REC…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors [Phase 1]
A Phase 1 study evaluating the safety and potential early efficacy of NST-628 oral tablets in adults with solid tumors is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Non-invasive Glioma Characterization Through Molecular Imaging [NA]
This clinical trial update describes a study evaluating non-invasive molecular imaging to characterize gliomas and other brain tumors. It is…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Mirdametinib in People With Central Nervous System Tumors [Phase 1, Phase 2]
This document provides an update on an ongoing Phase 1/Phase 2 clinical trial evaluating Mirdametinib in people with central nervous system …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study Utilizing Escitalopram in Glioma Patients [Phase 2]
A Phase 2 clinical trial is evaluating escitalopram in patients with glioma and is currently recruiting at the University of Nebraska.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma [EARLY_Phase 1]
This document describes an early-phase 1 clinical trial evaluating Plixorafenib alone or with Retifanlimab in patients with BRAF-altered gli…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas [Phase 1]
A Phase 1 study of ASTX727 is recruiting for recurrent/progressive non-enhancing IDH-mutant gliomas. The trial investigates the oral decitab…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Study of Letrozole in Recurrent Gliomas [EARLY_Phase 1]
An early-phase (Phase 1) study is investigating letrozole for recurrent gliomas (brain tumors). Recruitment is currently ongoing.
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CLINICAL_TRIALS other · 2026-04-14Clinical Trial Update: Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy [Phase 2]
This ClinicalTrials.gov entry describes a Phase 2 study investigating the biology of IDH-mutant gliomas by longitudinally tracking 2-hydroxy…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Sophrology Treatment for Patients With Glial Tumours Requiring Speech Therapy [NA]
A terminated clinical trial evaluating sophrology for patients with gliomas requiring speech therapy has posted results.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma [Phase 1]
This Clinical Trial Update describes a Phase 1 study of hypofractionated re-irradiation for good-prognosis recurrent glioblastoma, sponsored…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors [NA]
Observational study in recurrent central nervous system tumors to evaluate responses to various treatments in brain tumors, with ongoing rec…