Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma [EARLY_Phase 1]
Clinical trial update announcing an EARLY Phase 1 study of niraparib for newly diagnosed glioblastoma and recurrent glioma; the trial status…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Clinical, patHOlogical and Imaging Project of nEuro-oncology (HOPE)
HOPE (NCT05859659) is a clinical trial in neuro-oncology that is currently recruiting for brain cancers, including glioma and brain tumors. …
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients [EARLY_Phase 1]
Early-phase trial update reports completion of a Phase 1 study evaluating LY3214996 in combination with abemaciclib for recurrent glioblasto…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Pembrolizumab, Olaparib, and Temozolomide for People With Glioma [Phase 2]
Phase 2 clinical trial update for pembrolizumab, olaparib, and temozolomide in glioma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance) [Phase 3]
Phase 3 trial SIGMA is investigating safusidenib as maintenance therapy for IDH1-mutant glioma and related astrocytoma/oligodendroglioma sub…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas [NA]
A clinical trial evaluating magnetic resonance elastography (MRE) to differentiate radiation necrosis from recurrent glioma in patients with…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
A pediatric cancer survivor study focusing on symptom cluster heterogeneity and gut microbiota mechanisms is currently recruiting, including…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Methimazole in Patients With Progressive Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating methimazole in progressive glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Investigating Mechanistic Predictors of Interpatient Variability and Temozolomide (TMZ) Induced Haematological Toxicity for Glioma Patients
A University College Cork trial is investigating mechanistic predictors of interpatient variability and Temozolomide-induced hematological t…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
This ClinicalTrials.gov entry notes molecular testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program and indicates on…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype [NA]
Clinical trial update: pembrolizumab is being studied in patients with hypermutator phenotype recurrent malignant glioma; the trial is curre…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) [EARLY_Phase 1]
An early-phase imaging trial evaluating fluorescently labeled nivolumab-IRDye800 (Nivo800) for high-grade glioma, with the study currently n…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG [Phase 1]
Phase 1 safety study evaluating SBK2-ICG for fluorescence-guided imaging of malignant brain tumors, including glioma. The trial is currently…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma [NA]
This is a clinical trial update describing monitoring of neurological symptoms, treatment tolerance, and quality of life in IDH-mutated glio…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. [Phase 2, Phase 3]
The DETERMINE trial's Arm 07 is studying dabrafenib plus trametinib in patients with BRAF V600 mutation-positive cancers across age groups; …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas
This clinical trial aims to develop and apply an IDH mutation-targeted PET/MRI imaging framework to improve precision diagnosis of gliomas. …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors
A clinical trial is assessing a self-administered remote neurological examination via a mobile app for patients with brain tumors; the study…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors
This ClinicalTrials.gov update indicates the C-SMART trial, which assesses cognitive strategies, mindfulness, and rehabilitation therapy for…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma [Phase 2]
Phase 2 clinical trial assessing the combination of All-Trans Retinoic Acid (ATRA) with a PD-1 inhibitor in recurrent IDH-mutant glioma; rec…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Tessa Jowell BRAIN MATRIX - Platform Study
Platform-level update for the Tessa Jowell BRAIN MATRIX platform study in glioma; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: [18F]FET PET for Characterization of Progressive or Recurrent Glioma From Treatment Related Changes
Clinical trial update for a retrospective study using the radiotracer [18F]FET PET to characterize progressive or recurrent glioma after tre…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors [EARLY_Phase 1]
An early Phase 1 trial evaluates MeFAMP as an imaging agent for amino acid transport in brain tumors. The study targets recurrent glioma and…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma [Phase 1]
Phase 1 trial evaluating the combination of ruxolitinib with radiation and temozolomide for grade III gliomas and glioblastoma; the study is…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Development of MRF for Characterization of Brain Tumors After Radiotherapy [NA]
Development of a Magnetic Resonance Framework (MRF) to characterize brain tumors after radiotherapy, with recruitment ongoing at Case Compre…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations [Phase 2]
This Clinical Trial Update reports on a Phase 2 study of olaparib in patients with advanced glioma, cholangiocarcinoma, or other IDH1/IDH2-m…