Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma [Phase 1]
Phase 1 study of chlorotoxin-targeted CAR T cells targeting MMP2 in patients with recurrent glioblastoma and other recurrent gliomas. The tr…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab [Phase 1, Phase 2]
Clinical trial update for recurrent high-grade glioma treated with APG-157 in combination with bevacizumab, currently recruiting in Phase 1/…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors [Phase 1]
Phase 1 trial update for GNC-039, a tetra-specific antibody, in relapsed/refractory or metastatic solid tumors; currently recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Tumor Treating Fields for the Treatment of Brainstem Gliomas [NA]
An Emory University-sponsored clinical trial is enrolling participants to evaluate Tumor Treating Fields therapy for brainstem gliomas, a su…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ [Phase 2]
Phase 2 pilot study evaluating mirtazapine for dual treatment of depression and chemotherapy-induced nausea and vomiting in patients with hi…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma [NA]
Clinical trial update evaluating an ex vivo drug combination optimization platform for recurrent high-grade astrocytic glioma, currently rec…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Memory Perception Assessment in Central/Non-central Nervous System Cancers [NA]
Clinical trial update on memory perception assessment in central and non-central nervous system cancers; the study includes glioblastoma and…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas [Phase 1]
This Phase 1 clinical trial evaluates the feasibility of hyperpolarized 13C-pyruvate metabolic MRI for imaging infiltrating gliomas. The spo…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating fluoxetine in combination with cytotoxic lysosomal stress for glioma; the study is currently acti…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Registering Genomics and Imaging of Tumors (ReGIT)
The ReGIT trial (Registering Genomics and Imaging of Tumors) is currently recruiting patients with glioma, sponsored by Indiana University.
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Protoporphyrin Imaging in Multispectral Evaluation of Resections [NA]
A clinical trial from Medical University Innsbruck is evaluating protoporphyrin-based imaging for multispectral assessment of glioma resecti…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Prognostic IntraOperative Biomarkers ideNtification in Tumor rElatEd suRgery [NA]
A ClinicalTrials.gov listing for a study at Erasmus Medical Center evaluating intraoperative biomarkers to predict prognosis during tumor-re…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: ERP-Based Research on the Modulation of Remimazolam on Working Memory and Brain Network Mechanisms in Glioma Patients [NA]
A clinical trial update describing ERP-based research on how remimazolam may affect working memory and brain networks in glioma patients; th…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Radiolabeled TSPO Targeted Molecular Probe in Glioma
A study evaluating a radiolabeled TSPO-targeted molecular probe for imaging glioma has been listed. The trial status is not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Phase I Study of HMPL-306 for the Treatment of Gliomas With IDH1 and/or IDH2 Mutations [Phase 1]
Hutchmed is conducting a Phase I trial of HMPL-306 for gliomas with IDH1 and/or IDH2 mutations, and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population
A completed clinical trial evaluating the validity and reliability of the PRO-CTCAE for adult-type diffuse glioma patients in the Chinese po…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: ASCENT Intervention for Brain Tumor Patients [NA]
Clinical trial update for the ASCENT intervention in brain tumor patients shows recruitment is ongoing. The study targets malignant brain tu…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma [NA]
A clinical trial update describes using molecular profiling to tailor treatments for patients with high-grade glioma, aiming to improve indi…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: LIQUID BIOPSY IN Low-grade Glioma Patients [NA]
Clinical trial evaluating liquid biopsy for patients with low-grade glioma is currently Recruiting at University Hospital, Montpellier.
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: BC008-1A Injection for Recurrent CNS WHO G4 Glioma [Phase 1]
A Phase 1 study of BC008-1A Injection for recurrent central nervous system WHO Grade 4 glioma (including glioblastoma) is currently recruiti…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial [NA]
Clinical trial update for Proton Pulsed Reduced Dose Rate Radiotherapy (PPRDR) in recurrent CNS malignancies; the trial is currently recruit…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases
This clinical trial is evaluating amino acid PET/MRI for the evaluation of glioma and brain metastases. The study is currently recruiting an…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Amino Acid PET to Assess the Efficacy of IDH Inhibitor Treatments for IDH Mutated Gliomas
This clinical trial is evaluating amino acid PET as a tool to assess the efficacy of IDH inhibitor treatments in IDH-mutated gliomas; the st…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial [Phase 2]
Phase 2 single-arm study assessing the efficacy and safety of electroacupuncture-stimulated paclitaxel delivery across the blood-brain barri…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Study on The Sensitizing Effect of Sonodynamic Therapy on The Treatment of Brainstem Glioma With Radiotherapy and Chemotherapy and Survival Analysis [Phase 2]
Phase 2 clinical trial evaluating whether sonodynamic therapy sensitizes brainstem glioma to radiotherapy and chemotherapy, with planned sur…