Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma [NA]
This completed clinical trial update reports on tumor DNA and MRI/CT imaging findings in patients with grade III or grade IV malignant gliom…
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CLINICAL_TRIALS withdrawal · 2012-11-21Clinical Trial Update: Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma [Phase 1]
A Phase I trial of dasatinib in combination with protracted temozolomide for recurrent malignant glioma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastoma [Phase 2]
A Phase II trial evaluated sunitinib (Sutent) for recurrent anaplastic astrocytoma and glioblastoma. The results were posted in October 2012…
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CLINICAL_TRIALS trial_result · 2012-10-04Clinical Trial Update: BIBF 1120 in Recurrent Glioblastoma Multiforme [Phase 2]
A Phase 2 study of BIBF 1120 (nintedanib) for recurrent glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: Evaluation of the Irinotecan/Bevacizumab Association for Naive Unresectable Glioblastoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of irinotecan and bevacizumab for patients with naive unresectable glioblastoma has comp…
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: Dose Escalation Radiotherapy With Modulation of Intensity and Integrated Boost (SIB-IMRT) in the Treatment of Glioblastomas in Adults [Phase 1]
Phase 1 dose-escalation trial evaluating dose-intense radiotherapy with SIB-IMRT for glioblastoma in adults. The study has completed.
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Epothilone ZK-219477 in Treating Patients With Recurrent Glioblastoma [Phase 2]
A Phase 2 clinical trial evaluating Epothilone ZK-219477 for recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Glufosfamide in Treating Patients With Recurrent Glioblastoma Multiforme [Phase 2]
This clinical trial update describes the status of a Phase 2 study evaluating glufosfamide in patients with recurrent glioblastoma.
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CLINICAL_TRIALS research · 2012-09-24Clinical Trial Update: Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 3]
This is a Phase 3 clinical trial update comparing radiation therapy with and without temozolomide in patients with newly diagnosed glioblast…
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CLINICAL_TRIALS trial_result · 2012-09-10Clinical Trial Update: Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas [Phase 2]
This Phase 2 trial of Avastin in combination with temozolomide for unresectable or multifocal glioblastoma and gliosarcoma has completed and…
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumors [Phase 2]
A Phase 2 trial evaluated tandutinib in combination with bevacizumab for recurrent brain tumors, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM) [Phase 1, Phase 2]
Phase 1/2 trial of lomustine (CCNU) plus dasatinib in recurrent glioblastoma was terminated; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Glioma [Phase 3]
Phase 3 clinical trial evaluating intracranially implanted carmustine for newly diagnosed malignant glioma, assessing safety and efficacy. T…
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CLINICAL_TRIALS trial_result · 2012-07-27Clinical Trial Update: Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection [Phase 1]
Phase 1 exploratory study evaluating two investigational PI3K/mTOR inhibitors, XL765 (SAR245409) and XL147 (SAR245408), in patients with rec…
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Recurrent Malignant Glioma [NA]
A clinical trial update describes a safety and efficacy study of intracranially implanted Carmustine for recurrent malignant glioma, with th…
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Bevacizumab and Irinotecan to Treat Brain Tumors [Phase 2]
A Phase 2 trial evaluating bevacizumab in combination with irinotecan for high-grade gliomas was terminated, and results were posted in July…
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CLINICAL_TRIALS trial_result · 2012-05-04Clinical Trial Update: Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP) [Phase 1, Phase 2]
This clinical trial update assesses 18F-FLT PET-CT for defining tumor volumes in high-grade gliomas, including astrocytoma and glioblastoma,…
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Penicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With Glioblastoma [Phase 2]
A Phase 2 clinical trial evaluating penicillamine with a low copper diet and radiation therapy for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Suramin Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2]
A Phase 2 clinical trial evaluated suramin plus radiation therapy for newly diagnosed glioblastoma.
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1]
Phase 1 study evaluating the safety and dosing of gossypol (AT-101) with temozolomide with or without radiation therapy in newly diagnosed g…
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Pyrazoloacridine Followed by Radiation Therapy in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme [Phase 1, Phase 2]
A completed Phase 1/2 study evaluated pyrazoloacridine administered before radiation therapy in adults with newly diagnosed supratentorial g…
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM) [Phase 3]
Phase 3 trial evaluating NovoTTF-100A (Tumor Treating Fields) for recurrent glioblastoma multiforme has completed, per the update.
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: A Pilot Study of Using Video Images in Advance Care Planning in Malignant Glioma Patients [NA]
A pilot study conducted by Massachusetts General Hospital evaluated the use of video images in advance care planning for patients with malig…
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CLINICAL_TRIALS trial_result · 2012-04-26Clinical Trial Update: Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid [Phase 3]
Phase 3 trial update for fluorescence-guided resection of malignant gliomas using 5-aminolevulinic acid has completed.
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CLINICAL_TRIALS trial_result · 2012-04-17Clinical Trial Update: ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating ZD1839 (gefitinib) with oral irinotecan in young patients with refractory solid tumors, including glioblastoma, rha…