Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-03-11Clinical Trial Update: Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients [Phase 2]
This Phase 2 trial evaluates sunitinib given before and during radiotherapy in patients with newly diagnosed biopsy-only glioblastoma. The s…
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: Evaluation of [18F]-FMISO for Non Operated Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating [18F]-FMISO PET imaging for non-operated glioblastoma has completed.
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CLINICAL_TRIALS research · 2013-02-26Clinical Trial Update: Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery [NA]
This clinical trial update discusses the use of intraoperative MRI and 5-ALA guidance to improve the extent of resection in brain tumor surg…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG [Phase 1]
A Phase I trial evaluating imatinib (Gleevec) in combination with everolimus (RAD001) and hydroxyurea in patients with recurrent glioblastom…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas [Phase 1]
A Phase I trial evaluated adding a Farnesyl Transferase Inhibitor to temozolomide in patients with Grade 3-4 malignant gliomas, and the stud…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Ph I Dose Escalation Trial of Vandetanib in Combo w Etoposide for Malignant Gliomas [Phase 1]
Phase I dose-escalation study of Vandetanib in combination with Etoposide for malignant gliomas (glioblastoma and gliosarcoma) has completed…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas [Phase 1]
A Phase 1 clinical trial evaluating the combination of Carmustine wafers and Irinotecan for patients with recurrent supratentorial high-grad…
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: RO4929097 in Treating Patients With Recurrent Invasive Gliomas [Phase 1]
Phase 1 trial update for RO4929097 in recurrent invasive gliomas has been terminated.
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CLINICAL_TRIALS trial_result · 2013-02-04Clinical Trial Update: Ph II Bev + Either Temozolomide/Etoposide for GBM Pts Who Have Failed Bev + Irinotecan [Phase 2]
Phase II trial evaluating bevacizumab with temozolomide or etoposide in glioblastoma or gliosarcoma patients who progressed after bevacizuma…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Bortezomib in Treating Patients With Recurrent Glioma [Phase 1]
Phase 1 trial evaluating bortezomib in adults with recurrent glioma; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant plus adjuvant fenretinide versus adjuvant fenretinide alone in patients undergoing surgery for…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas [Phase 2]
Phase 2 trial evaluating Avastin with radiation and temozolomide, followed by Avastin, temozolomide and irinotecan in glioblastoma and glios…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating Avastin with radiation and temozolomide, followed by Avastin/temozolomide/topotecan in glioblastoma patien…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction [Phase 1]
Phase 1 clinical trial evaluating erlotinib in patients with solid tumors and liver or kidney dysfunction has been completed.
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CLINICAL_TRIALS research · 2013-01-16Clinical Trial Update: Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma [NA]
A terminated clinical trial evaluated the use of EF5 to measure oxygen levels in tumor cells of patients with newly diagnosed supratentorial…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors [Phase 1]
This document is a terminated Phase 1 trial update evaluating PET imaging with 18F-EF5 to measure oxygenation in brain tumor cells of adults…
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CLINICAL_TRIALS trial_result · 2013-01-14Clinical Trial Update: Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma [Phase 2]
Phase 2 clinical trial update evaluating imatinib mesylate in combination with hydroxyurea for patients with recurrent or progressive gliobl…
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FDA approval · 2013-01-08FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for TEMODAR (temozolomide) submitted by Merck Sharp & Dohme LLC, resulting in an approved change…
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CLINICAL_TRIALS trial_result · 2013-01-08Clinical Trial Update: Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)
This is a post-marketing surveillance protocol update for Temozolomide (Temodal) in patients with glioblastoma, glioma, and astrocytoma; the…
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CLINICAL_TRIALS trial_result · 2012-12-21Clinical Trial Update: Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma [Phase 3]
A Phase 3 trial evaluated cediranib in combination with lomustine for recurrent glioblastoma; the study has completed and results were poste…
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CLINICAL_TRIALS trial_result · 2012-12-18Clinical Trial Update: Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients
Clinical trial update on using combined [18F]FET PET and simultaneous MRI for follow-up in patients with recurrent glioblastoma that have be…
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CLINICAL_TRIALS trial_result · 2012-12-13Clinical Trial Update: Randomized Phase 2 With CpG-ODN in Malignant Glioblastoma [Phase 2]
A randomized Phase 2 trial evaluating CpG-ODN in glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2012-12-05Clinical Trial Update: Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Glioma [Phase 1]
Phase 1 trial evaluating vandetanib (Zactima) in combination with imatinib mesylate and hydroxyurea for recurrent malignant glioma (glioblas…
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: Nimotuzumab in Adults With Glioblastoma Multiforma [Phase 3]
A Phase 3 trial evaluating nimotuzumab in adults with glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: Procarbazine and Lomustine in Recurrent Glioblastoma [Phase 2]
This entry notes a Phase 2 clinical trial evaluating the combination of procarbazine and lomustine for recurrent glioblastoma. The update do…