Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery [Phase 1]
This clinical trial update reports on a Phase 1 study of the oncolytic herpes simplex virus HSV-1716 in children with refractory or recurren…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Cellular Immunotherapy Study for Brain Cancer [Phase 1]
Phase 1 clinical trial update describes completion of a cellular immunotherapy study for brain tumors to assess safety and initial signals o…
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas [Phase 1, Phase 2]
Clinical trial update on 5-ALA hydrochloride for fluorescence-guided resection of malignant gliomas (Phase 1/Phase 2), now completed.
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Safety and Efficacy of Talampanel in Glioblastoma Multiforme [Phase 2]
Phase 2 trial results evaluate the safety and efficacy of Talampanel in Glioblastoma. The update reports outcomes from the Phase 2 study con…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Dendritic Cell Cancer Vaccine for High-grade Glioma [Phase 2]
Phase 2 trial of a dendritic cell cancer vaccine for glioblastoma has completed.
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CLINICAL_TRIALS withdrawal · 2016-05-17Clinical Trial Update: More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery [Phase 2]
A Phase 2 trial investigating fluorescence-guided surgery for removing malignant brain tumors has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy [NA]
A completed trial evaluated MRI using ferumoxytol to assess early response in patients with glioblastoma receiving temozolomide and radiatio…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Dendritic Cell-Based Tumor Vaccine Adjuvant Immunotherapy of Human Glioblastoma Multiforme (WHO Grade IV Gliomas) [Phase 2]
A Phase 2 clinical trial investigating a dendritic cell–based tumor vaccine as adjuvant immunotherapy for glioblastoma.
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating the safety and tolerability of macitentan in combination with dose-dense temozolomide in recurrent glioblastoma has…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Erlotinib and Sorafenib in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme [Phase 2]
Phase 2 trial update of erlotinib and sorafenib in progressive or recurrent glioblastoma multiforme; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma [Phase 1]
Phase 1 trial evaluating temozolomide with radiation therapy for newly diagnosed glioblastoma and anaplastic astrocytoma; results have been …
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Pilot Study of Bone Marrow/Stem Cells in Grade IV Malignant Glioma [Phase 1]
A Phase 1 pilot study tested the safety of bone marrow-derived stem cells in patients with glioblastoma; the trial has completed.
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma [Phase 1, Phase 2]
A completed Phase I/II clinical trial evaluating IMA950 multi-peptide vaccine plus Poly-ICLC in adults with glioblastoma.
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Dovitinib (TKI258) in the Treatment of Patients With Relapsed Glioblastoma [Phase 1]
Phase 1 clinical trial update of dovitinib (TKI258) in patients with relapsed glioblastoma (first or second recurrence).
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
Clinical trial update for Temsirolimus and Perifosine in recurrent or progressive malignant glioma (Phase 1/2) with completed status and pos…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas [Phase 2]
Results from a Phase II randomized trial in adults with recurrent high-grade gliomas comparing vandetanib with carboplatin followed by vande…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors [Phase 2]
Phase 2 study evaluating aminolevulinic acid to enhance visualization and surgical removal of brain tumors has been terminated.
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CLINICAL_TRIALS withdrawal · 2016-03-16Clinical Trial Update: A Phase III Study of Re-Irradiation in Recurrent Glioblastoma [Phase 3]
A Phase III study evaluating re-irradiation for recurrent glioblastoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Post-approval Study of NovoTTF-100A in Recurrent GBM Patients [Phase 4]
A post-approval Phase 4 study of NovoTTF-100A in patients with recurrent glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Sunitinib in Treating Patients With Recurrent Malignant Gliomas [Phase 2]
Phase 2 trial evaluating sunitinib for adults with recurrent malignant gliomas has completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma [Phase 2]
This Phase 2 clinical trial update reports results for temozolomide in patients with recurrent glioblastoma multiforme or other malignant gl…
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CLINICAL_TRIALS research · 2016-02-26Clinical Trial Update: Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221
Expanded Access Protocol update for glioblastoma patients who already have manufactured DCVax-L and failed screening under protocol 020221; …
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma [Phase 3]
A Phase 3 clinical trial evaluating conventional adjuvant temozolomide with dose-intensive temozolomide in newly diagnosed Glioblastoma has …
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1, Phase 2]
ClinicalTrials.gov indicates a completed Phase 1/2 study evaluating cilengitide with temozolomide and radiation for newly diagnosed glioblas…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide [Phase 1, Phase 2]
This document reports the completion of a Phase 1/2 clinical trial evaluating magnetic resonance spectroscopic imaging and tumor perfusion i…