Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss [Phase 1, Phase 2]
The document provides an update on a Phase 1/2 clinical trial assessing the safety and tolerability of TNG456 alone and with abemaciclib in …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma [Phase 2]
A Phase 2 clinical trial update examining the combination of dabrafenib and trametinib after radiation therapy for newly diagnosed high-grad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients [NA]
Clinical trial update on combining the NaviFUS System with re-irradiation for recurrent glioblastoma and high-grade glioma (WHO III–IV); the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma [Phase 2]
Phase 2 trial evaluating Mirdametinib alone or with radiotherapy for germline and sporadic NF1-altered high-grade glioma; status is not yet …
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the combination of ipilimumab and nivolumab in patients with recurrent gliom…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA [Phase 2]
Phase 2 clinical trial investigating super selective intra-arterial cetuximab with reirradiation for relapsed or refractory glioblastoma, an…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas [Phase 1]
Phase 1 clinical trial update exploring vorinostat with temozolomide for malignant gliomas in adults, with active-not-recruiting status acro…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM [Phase 1]
Trial update for a Phase 1 CART-T therapy called CART-EGFR-IL13Ra2 in EGFR-amplified recurrent glioblastoma; the study is currently active b…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating oral NBM-BMX in patients with solid tumors or newly diagnosed glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients [Phase 3]
A Phase 3 prospective study evaluating bevacizumab with or without microbubble-mediated focused ultrasound (NaviFUS) in recurrent glioblasto…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients [NA]
Completed clinical trial evaluating the NaviFUS system as an add-on to Bevacizumab for recurrent glioblastoma, reporting efficacy and safety…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Clinical Study on the Safety and Immunogenicity of Specific Cancer Vaccines in Preventing Recurrence of Glioblastoma [EARLY_Phase 1]
An early-phase clinical trial is evaluating the safety and immunogenicity of cancer vaccines aimed at preventing glioblastoma recurrence. Th…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. [Phase 1]
A Phase 1 trial is evaluating whether immunotherapy can be safely given to adults with glioblastoma or gliosarcoma before their standard tre…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma [NA]
This document reports the completion of a clinical trial evaluating metabolic therapy in conjunction with standard treatment for Glioblastom…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) [Phase 1, Phase 2]
A clinical trial update on safety and efficacy of combining bevacizumab with the NaviFUS system for recurrent glioblastoma multiforme, curre…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma [Phase 1]
This Clinical Trial Update describes a Phase 1 study of hypofractionated re-irradiation for good-prognosis recurrent glioblastoma, sponsored…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating laser interstitial thermotherapy (LITT) combined with a checkpoint inhibitor for recurrent glioblastoma;…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Glioblastoma Remote Monitoring and Care - Research Protocol [NA]
This document outlines a remote monitoring and care research protocol for patients with glioblastoma, including considerations for venous th…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Oral Gallium Maltolate for Recurrent Glioblastoma [EARLY_Phase 1]
This document reports an early-phase clinical trial evaluating oral gallium maltolate for recurrent Glioblastoma; the study is not yet recru…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1]
A Phase 1 pediatric trial of SurVaxM for progressive or relapsed medulloblastoma, high-grade glioma, ependymoma, and newly diagnosed diffuse…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Prophylactic Regimen With Intrathecal Thiotepa in SVZ-positive or Meningeal-risk Glioblastoma [Phase 2]
A Phase 2 clinical trial is evaluating prophylactic intrathecal thiotepa for SVZ-positive or meninges-risk glioblastoma, currently recruitin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma [NA]
A clinical trial update indicates Alpha Tau Medical's DaRT alpha radiation emitter device is being studied for recurrent glioblastoma and re…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Mental Health and Suicidality in Glioblastoma Patients in Germany
This clinical trial update indicates that recruitment is ongoing for a study examining mental health and suicidality among glioblastoma pati…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4) [NA]
A clinical trial is evaluating local targeted alpha emitter therapy using 225Ac-DOTA-SP (TAT) for newly diagnosed glioma (WHO grade 3-4) and…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Phase I Study to Evaluate the Safety and Tolerability of JL15003 Injection in Patients With Recurrent Glioblastoma [Phase 1]
Phase I study evaluating safety and tolerability of JL15003 injection in patients with recurrent glioblastoma has completed.