Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors [Phase 1]
Clinical trial update indicating that Loc3CAR (B7-H3-CAR T cells) delivery is in early-phase pediatric CNS tumor trials and currently recrui…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Evaluation of UCPVax Vaccine +/- Pembrolizumab Combined With Standard Treatment as Adjuvant Therapy in Patients With Unmethylated MGMT Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating UCPVax vaccine with or without pembrolizumab added to standard therapy for unmethylated MGMT glioblastoma;…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of Radiochemotherapy [NA]
This clinical trial update describes a study evaluating biomarkers that predict 6-month survival for glioblastoma patients at first relapse …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Control Cohort CTRL COH [NA]
A status update for a control cohort in a Hospices Civils de Lyon trial, with recruitment ongoing for Parkinson's disease, amyotrophic later…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma [Phase 1]
Phase 1 trial evaluating mycophenolate mofetil in combination with standard of care for glioblastoma; study status is ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma [Phase 2]
Phase 2 clinical trial evaluating Gallium-68 PSMA-11 PET/CT for detecting recurrence or progression in high-grade gliomas (WHO Grade 3 and G…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas [Phase 2]
A Phase 2 clinical trial from MD Anderson is evaluating chemotherapy and radiation therapy for IDH-wildtype gliomas and non-histological (mo…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: BIO-SHORT: Biologically Guided Short-Course Hypofractionated RT for Poor-Prognosis GBM [Phase 2]
BIO-SHORT is a Phase 2 trial evaluating biologically guided short-course hypofractionated radiotherapy for poorly prognostic glioblastoma. T…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 trial comparing dose-escalated photon IMRT or proton beam radiation therapy with standard-dose radiation therapy plus temozolomide i…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Antisecretory Factor Glioblastoma Phase 2 [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating antisecretory factor for glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab [Phase 2]
A Phase 2 trial evaluating the combination of nivolumab and relatlimab for newly diagnosed glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer [Phase 1]
A Phase 1 trial evaluating the safety of a chemo-immunotherapy combo of ibrutinib and indoximod in pediatric brain tumor patients, including…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma [Phase 1]
Phase 1 trial evaluating Carmustine wafer in combination with Retifanlimab and radiation, with or without temozolomide, in glioblastoma.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma [Phase 2]
Phase 2 clinical trial update from University Hospital Tuebingen investigating protective VEGF inhibition for isotoxic dose escalation in gl…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Niraparib/TTFields in GBM [Phase 2]
Phase 2 trial evaluating niraparib in combination with TTFields for glioblastoma is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG [Phase 2]
Phase 2 pediatric trial evaluating indoximod with chemotherapy and radiation for relapsed brain tumors or newly diagnosed diffuse intrinsic …
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial [Phase 2]
A Phase 2 randomized trial assessing the combination of OPTune GIO (tumor treating fields device) with MRI-guided laser ablation and pembrol…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Natural Progesterone for the Treatment of Recurrent Glioblastoma [EARLY_Phase 1]
A Phase 1 study of natural progesterone for recurrent glioblastoma and gliosarcoma is being conducted by Emory University, with status liste…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas [EARLY_Phase 1]
A terminated early-phase 1 trial evaluated repurposed ketoconazole for glioblastoma, reporting on its neuro-pharmacological properties.
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Nivolumab With Radiation Therapy and Bevacizumab for Recurrent MGMT Methylated Glioblastoma [Phase 2]
This is a Phase 2 clinical trial evaluating nivolumab with radiation therapy and bevacizumab for recurrent MGMT-methylated glioblastoma; the…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Impact of the Platelet Level in Patients Treated for Glioblastoma With Temozolomid [Phase 2]
Phase 2 trial update examining how platelet levels influence outcomes in glioblastoma patients treated with temozolomide.
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
This clinical trial update describes the CCANED-CIPHER study, an ongoing investigation using AI-based transcriptomic profiling of platelets …
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Newly Diagnosed Glioblastoma [Phase 2]
A Phase 2 clinical trial for newly diagnosed Glioblastoma is active but not recruiting, sponsored by Sun Yat-sen University.
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: A Study of VRT106 for Injection in Patients With Recurrent/Progressive Glioblastoma [Phase 1, Phase 2]
This entry describes an ongoing Phase 1/2 clinical trial evaluating VRT106 for injection in patients with recurrent or progressive glioblast…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma [Phase 1]
Phase 1 dose-escalation trial of re-irradiation in good-prognosis recurrent glioblastoma has completed.